Posted on 08/05/2021 2:04:11 PM PDT by ConservativeMind
A study has identified new factors accompanying previous findings that frequent consumption of peanuts by cancer patients could increase risk of cancer spread.
The study shows that Peanut agglutinin (PNA) -- a carbohydrate-binding protein that rapidly enters into the blood circulation after peanuts are eaten -- interacts with blood vascular wall (endothelial) cells to produce molecules called cytokines.
The cytokines, IL-6 and MCP-1 are well-known promoters of cancer metastasis. The increased cytokine production causes other endothelial cells to express more cell surface adhesion molecules, making them more attractive to the circulating tumour cells and thus potentially promoting metastasis.
In an earlier study, Corresponding Author Professor Lu-Gang Yu and colleagues reported that circulating PNA binds to a special sugar chain, which occurs mainly on pre-cancerous and cancer cells, and interacts with a larger protein expressed on the surface of tumour cells in the bloodstream.
This interaction triggers changes in the larger protein, resulting in underlying adhesion molecules on the surface of the cancer cell to become exposed, making the cancer cells stickier and easier to attach themselves to the blood vessels. It also allows the cancer cells to form small clumps that prolong the survival of cancer cells in the body's circulation. Many epithelial cancers spread to the other organs through traveling through the bloodstream.
"In our previous healthy volunteer study, substantial blood concentrations of PNA were only seen transiently one hour or so after consumption of a large dose (250g) of peanuts…
"Nevertheless, the possibility remains that circulating PNA, at least at the relatively high levels found shortly after a large "dose" of peanuts, could have a significant biological effect on tumour cells circulating at that time, with a potential for increased risk of metastasis. Heavy or very frequent peanut consumption therefore might be better avoided by cancer patients."
(Excerpt) Read more at sciencedaily.com ...
Or it could be the ChiComs are trying to mess with the peanut market and US peanut farmers.
So all the fun foods are ‘bad’ for you,
and all the yucky, ugly looking foods are ‘good’ for you.
To that I’ll say “Moderation in all things!”
Increased ACE2 expression?
A study that I can’t recall points to ACE1 down-regulators (e.g., diabetic meds) may trigger a rise in ACE2 expression — fertile ground for SARS.
Jimmy Carter’s fault ...
Almond butter is better in my opinion.
I consume so many peanuts I ooze peanut oil.
Next they are going to tell me bacon is bad.
George Washing5ton Carver, Friend or Fiend?
A couple years ago I bought a used truck out of California. There was a Prop. 65 cancer warning label on the window. I contacted the dealer and asked him what that was for. He said they had found residue of peanut butter on the steering wheel.
I have cancer, and I was literally sitting here eating peanuts when I saw this headline you posted.
I’m sorry to hear that. May I ask what specific form?
Mouth, under the tongue. I caught it early so I just had surgery, no chemo or radiation, and it hasn’t resurfaced for 1.5 years. I better put those peanuts down.
That’s a whole different shell game.
Bull crap.
Please tell me that this DOESN’T include Jif Creamy PB.
Should that cancer come back in some form, please reach out to me and I will dig up what best options you might have from all recent medical studies.
Keep up the good efforts to thwart this terrible disease.
Thank you!
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