Posted on 07/02/2021 9:46:24 PM PDT by MinorityRepublican
I was an early proponent of HCQ. Seemed like a miracle pill and it was our first best hope. But if there’s any ‘secret’ to HCQ and Ivermectin learned since is it has to be used either very early or very late - a lot of the studies say before day 7. And, with a 98% survival rate anyway, is it the HCQ or would the ‘early’ users have survived anyway?
I’d also point to Brazil - HCQ and Iver have been in heavy use at street level for over a year now, openly encouraged by Bolsonaro, at different dosing and different intervals. Invermectin is $5 for 4 and HCQ kits are sold cheaply at the local pharmacies. But even with neighborhood-level distribution, their survival rate fell below 98% and younger people got sicker. If HCQ was a miracle pill, the opposite would be true, even adjusted for poverty.
According to a recent pre-print observational study that is being panned, on already ventilated patients at very high doses “specifically those receiving >3,000mg HCQ and >1g azithromycin” there might be some effect, but serum levels were cumulative, and 80% of the patients died out of 88%. It’s claimed in the comments that to get to cumulative serum levels one would have to survive a further 10 days minimum while dosed (weight dependent):
https://www.medrxiv.org/content/10.1101/2021.05.28.21258012v1
Here’s a synopsis of the very early HCQ studies, even some since discredited. All point to “early treatment’ as the key to their optimism. But none are as optimistic as invermectin, and neither are as effective as clinical treatments developed in the past year.
http://www.hydroxystudy.info/1.pdf
The vaccine isn’t perfect, but even after 18 months, we don’t have a magic pill, either.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.