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COVID-19 vaccine breakthrough case investigation Information for state and local health departments
CDC ^ | CDC

Posted on 04/21/2021 10:50:22 AM PDT by Cathi

CDC will monitor NNDSS and the Vaccine Adverse Event Reporting System (VAERS) for additional cases and will upload available data reported to those systems into the COVID-19 vaccine breakthrough REDCap database for your review and confirmation.

6. Ultimately, CDC will use the National Notifiable Diseases Surveillance System (NNDSS) to identify vaccine breakthrough cases. Once CDC has confirmed that a state can report vaccination history data to NNDSS, CDC will identify vaccine breakthrough cases through that system.

At that time, the state health department will stop reporting cases directly into the national COVID-19 vaccine breakthrough REDCap database. CDC will upload the available data reported to NNDSS into the COVID-19 vaccine breakthrough REDCap database for further review and confirmation by the state health department.

7. In the coming weeks, CDC will transition this surveillance activity to focus on identifying and investigating only those vaccine breakthrough infections that result in hospitalization or death. This shift will help maximize the quality of the data collected on cases of greatest clinical and public health importance.


TOPICS: Health/Medicine
KEYWORDS: covid; covid19; vaccine; vaccinebreakthrough; vaers

1 posted on 04/21/2021 10:50:22 AM PDT by Cathi
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To: All

I thought they only wanted to suppress adverse reactions. Is this a policy change?


2 posted on 04/21/2021 10:53:08 AM PDT by BipolarBob (Jeffrey Epsteins last words "I am not committing suicide".)
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To: Cathi

if i was a red state, i’d keep my own data separate from dc. certainly our hospitals should keep their own data.

they’re always trying to hide what they’re doing to us.


3 posted on 04/21/2021 10:55:38 AM PDT by dadfly
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To: Cathi

This was supposed to be done before making the vaccines available to everyone. Hope you enjoy being an unpaid ginea pig.


4 posted on 04/21/2021 10:56:34 AM PDT by P-Marlowe (Freep mail me if you want to be on my Fingerstyle Acoustic Guitar Ping List )
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To: Cathi

Feel free to vent to VAERS - atty statement [name withheld]

sophisticated targeted genocide? /tinfoil hat


5 posted on 04/21/2021 10:57:14 AM PDT by PGalt (past peak civilization?)
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To: BipolarBob

It’s a new program they are in the process of setting up. Apparently they would like to “suppress” public awareness of breakthrough data as well. They are getting a lot of it early on...:-(

Dr. Risch: “The vaccination, because it only cuts transmission by 50 to 60% and not by 90%, it’s not that strong to shut off the infection.”


6 posted on 04/21/2021 10:59:35 AM PDT by Cathi
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To: Cathi

It is becoming more apparent everyday that the safest way to combat the Fauci Flu, is to Contract it, take Ivermectin to recover quickly and enjoy Natural Immunity for LIFE!!!


7 posted on 04/21/2021 11:08:43 AM PDT by eyeamok (founded in cynicism, wrapped in sarcasm)
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To: eyeamok

Interesting perspective from Dr. Harvey Risch, MD, Ph.D. Yale University Professor of Epidemiology & Public Health

It’s irrational and we’ve made everything that’s in the grey zone and in a quantitative amount into a binary yes/no. And it really.... it doesn’t work for policy and it doesn’t work for science. Vaccination is one contribution.

We now have an assay called T-Detect that can measure T cell immunity....we know that T cell immunity from Sars 1 in 2003 people will still have... who had Sars 1... will still have it 17 years later. So immunity to this virus is not just...Oh we can measure the antibodies...they last 6 to 9 months and then it’s gone. That isn’t the whole story. The T cell contribution is an important contribution to immunity and that lasts much longer and now we can measure it and so now the question is...Why aren’t we doing that to see who’s really immune and doesn’t need vaccination and I think that this again becomes...Oh, this is just too complicated we just need you know, vaccine or not, it’s simple we can just do that. We can’t do T detection; we can’t measure people it’s too complicated.

I think we have to gradually bite the bullet and do the real science.


8 posted on 04/21/2021 11:14:08 AM PDT by Cathi
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To: Cathi

(1) Having been previously infected with covid provides antibodies and T cell response magnitudes higher than one dose of the vax provides.

(2) The Pfizer vax produced weak T cell response at least after one dose.

(3) And most interesting T cells can help to recognise different viral variants, they are somewhat less susceptible to loss of immune recognition against viral variants than antibody responses.

A single amino acid can make a big change in the structure, and that means a lot of antibodies can’t bind. Whereas T cells see little peptide fragments, the virus is stripped into fragments and therefore the T cell response is not so badly lost against single amino acid changes.”


9 posted on 04/21/2021 11:19:56 AM PDT by Cathi
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To: dadfly

What do you mean? The data IS kept by the hospitals and by the states. The hospital reports to the health department (state or local depending on the reporting jurisdiction), who then aggregates it with everyone else’s and passes it along to CDC. That’s why CDC’s data is often weeks out of date; local and state officials are often incredibly slow to process and forward the data.

But it’s not like that data is lost when they send it to CDC. They send a copy of what they have. CDC simply compiles the data everyone sends them and publishes it.

Did you think CDC had people in every hospital in America compiling data and keeping it from the hospital or something? Because that’s definitely not how it works at all.


10 posted on 04/21/2021 11:53:45 AM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: eyeamok

That’s not how things work in the real world:

https://www.thelancet.com/article/S0140-6736(21)00183-5/fulltext

Brazil and South Africa demonstrate that the immunity provided by infection by one variant is not necessarily robust when exposed to other variants.


11 posted on 04/21/2021 12:04:41 PM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: Cathi
Why aren’t we doing that to see who’s really immune and doesn’t need vaccination and I think that this again becomes...I think we have to gradually bite the bullet and do the real science.

'We' is not 'they' and the problem is 'they' have other priorities...certainly NOT our optimum health, let alone the actual science and facts (not their 'truths').

12 posted on 04/21/2021 12:17:37 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: 2aProtectsTheRest

That study only cited 2 cases of reinfection, there are less than 100 Documented Cases of Reinfection worldwide since this began. They come close only once with this Statement:

“SARS-CoV-2 lineages might evade immunity generated in response to previous infection.”

Which is Scientifically and Functionally equivalent to this Statement:

Elephants Might be able to Fly if they flap their ears fast enough!

Try the study from Fauci and his Group at NIH

Lasting immunity found after recovery from COVID-19

95% of the people had at least 3 out of 5 immune-system components that could recognize SARS-CoV-2 up to 8 months after infection

https://www.nih.gov/news-events/nih-research-matters/lasting-immunity-found-after-recovery-covid-19


13 posted on 04/21/2021 12:19:57 PM PDT by eyeamok (founded in cynicism, wrapped in sarcasm)
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To: Cathi

Hmmm...I missed that they had this new test - T-Detect Covid, authorized by FDA just a few weeks ago - by Adaptive. Thanks for mentioning it.

Linked below for those interested.

https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-adaptive-biotechnologies-t-detect-covid-test


14 posted on 04/21/2021 12:26:37 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: eyeamok

There are a lot more than 100 cases of reinfection worldwide. The Novavax clinical trials in South Africa alone documented almost 1,500 cases where previously infected persons were reinfected during the trials.

https://www.forbes.com/sites/williamhaseltine/2021/03/10/covid-19-reinfections-are-real-and-serious-all-the-more-reason-to-be-vaccinated/?sh=2839778012e2

The seroprevalence of SARS-CoV-2 antibodies in Manaus (Brazil) prior to P.1 (Brazil variant) emergence would make it all but impossible for them to hit the infection numbers they did without P.1 reinfecting people.

The neutralizing antibodies are present and effective for long periods of time (experience with SARS2003 and MERS2012 suggests 1-3 years). However, structural changes in the S protein of the P.1 and the South Africa variants make the neutralizing antibodies for the April 2020 variant (and the original Wuhan variant) less effective because the binding site has changed such that the “key” doesn’t quite fit the “lock” the same way. If you jam enough keys in there, you’ll eventually get it right, but it’s no longer a good and easy fit.


15 posted on 04/21/2021 12:45:46 PM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: Cathi
"the antibodies...they last 6 to 9 months and then it’s gone."

That isn't really how the antibodies work either. Antibodies are produced by a lymphocyte called B cells. During an infection, dendritic cells take samples of the pathogen's antigen to lymph nodes where a complicated process churns out custom T cells. Those T cells in turn activate specific B cells, which then mass reproduce, then produce antibodies. Most of those B cells will literally work themselves to death.

After the infection has been defeated, most of the B cells (roughly 90%) will die. They're no longer needed and they use a lot of the body's energy. The remaining B cells that had been active become dormant and remain as Memory B cells. Should the same pathogen be encountered in the future, those B cells can reactivate and kick off the antibody production process again. The benefit here is it's much, much faster than having to go through the entire process. They'll just mass reproduce immediately upon T cell activation and churn out antibodies to overwhelm the infection.

So even after the antibodies are "gone", immunity is still very much intact. However, if there are significant changes to the antigens, that pathogen may not be recognized as being the same and that reactivation process will not happen. And minor changes to the binding site for the antibodies can render them less effective or entirely ineffective, leading to a more protracted battle happening all over again.

16 posted on 04/21/2021 12:56:15 PM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: Cathi

The chief medical officer of BioNTech told CNBC that people will likely need a third shot of its two-dose Covid-19 vaccine as immunity against the virus wanes.

Dr. Ozlem Tureci, the co-founder and CMO of BioNTech, which developed a Covid vaccine with Pfizer, said she also expects people will need to get vaccinated against the coronavirus annually, like for the seasonal flu.


17 posted on 04/21/2021 1:20:52 PM PDT by Cathi
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To: 2aProtectsTheRest

Each health department does ‘their own thing’ essentially ie in how they ultimately define parameters of a breakthrough and which ones they fully investigate and report. THEN they report to CDC. They don’t even test every breakthrough to ID the variant. In addition although all + Covid cases are reported to health departments, all vaccines are not. Thus all breakthrough cases are not investigated, because don’t have proof on record of their vaccination. Believe me. I am a health department nurse


18 posted on 04/21/2021 4:44:54 PM PDT by dkGba (God Bless America dkGba)
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To: 2aProtectsTheRest

To date worldwide, fewer than 100 confirmed cases of reinfection have been reported. These are instances in which people infected with the coronavirus have become sick with the virus again after full recovery, according to Ethelberg and his colleagues.

https://www.upi.com/Health_News/2021/03/17/coronavirus-reinfection-study/8961616008058/


19 posted on 04/21/2021 4:56:53 PM PDT by eyeamok (founded in cynicism, wrapped in sarcasm)
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