in baby’s English please
Correct me if I am wrong, but this sounds a lot like saying “Not as effective in the older population”.
The efficacy of the vaccine is age dependent. Younger people will have stronger, longer lasting protection. The elderly (in this case people over 80) will have weaker, shorter lasting protection and will need to be revaccinated more frequently according to this study.
“in baby’s English please”
Remember the two doses for Pfizer or Moderna?
If you’re elderly...make that three doses, or four, or five. After all, they ARE experimental vaccines.
It is not working as well in old people who need it much more, than in young people who basically don’t need it at all.
Immune systems have “learning” and “memory”, but these functions become less effective as we age. Basically, our immune system gets age related dementia just like our brains do and don’t learn new pathogens or remember old pathogens and so don’t produce antibodies for them.
This is why people who had chicken pox as children need a shingles vax at 60, to make sure the immune system remembers to make antibodies to prevent the reactivation of the virus.
Some people are born with immune systems that are village idiots and do not develop vaccine induced immunity at all. This is why no vaccine ever is 100% effective.
Vaccines no work for old people. More risk for no or little immune response.