Posted on 02/27/2021 8:30:04 AM PST by Capt. Tom
Johnson & Johnson’s single-shot coronavirus vaccine has been recommended for emergency use authorization by an independent advisory committee, setting it up to get the green light from the FDA and mark the third vaccine available in the United States.
Johnson & Johnson’s single-dose vaccine protects against COVID-19, according to an analysis by U.S. regulators Wednesday, Feb. 24, 2021, that sets the stage for a final decision on a new and easier-to-use shot to help tame the pandemic.
The Food and Drug Administration’s scientists confirmed that overall, it’s about 66% effective and also said J&J’s shot, one that could help speed vaccinations by Johnson & Johnson’s single-dose vaccine protects against COVID-19, according to an analysis by U.S. regulators Wednesday, Feb. 24, 2021, that sets the stage for a final decision on a new and easier-to-use shot to help tame the pandemic.
The Food and Drug Administration’s scientists confirmed that overall, it’s about 66% effective and also said J&J’s shot, one that could help speed vaccinations by requiring just one dose instead of two, is safe to use.
(Excerpt) Read more at msn.com ...
Az and JnJ vaccines use an adenovirus vector approach.
I am sure.
I will look for up the papers I read to prove it...link coming.
https://www.nbcnews.com/health/health-news/how-cells-taken-decades-old-fetal-tissue-are-used-covid-n1242740
"Three Covid-19 vaccine candidates that have received federal funding through the White House’s Operation Warp Speed have also used cells from fetal tissue in their research. AstraZeneca and Moderna both used the HEK293T cell line in early studies on their vaccines. Johnson & Johnson used a different cell line called PER.C6, also derived from fetal cells, to test its vaccine’s effectiveness against Covid-19."
bookmark
Agree, those numbers are pretty crappy - just take Ivermectin and you’ll have better results.
I was going to tell my kids to take the J&J (since they’ll have to take something to move into new, friendlier, countries), and I still may tell them it’s ok, given their ages. I do want them to be able to have (normal) kids, so avoiding the mRNA types (double-dose vaccines) seems to make sense for them.
Really?
What recombinant DNA lab did you work in?
Where did you do your graduate studies? I studied T4 , do you even know what that is?
You think the JnJ vaccine is not delivered through an adenovirus vector?
Please - show us.
IMO, the adenovirus vector vaccines are at least as scary as the mRNA vaccines.
“Gene therepy”
Derp!
Genes are contained in chromosomes which are INSIDE the cells nucleus, messenger RNA never enters inside a cell nucleus!
Derp!
Your Post Toasties you’ve eaten every day for the last 20 years does include genetically modified corn, so you are a walking mutant already! LOL
I am aware of the adenovirus vector. If you are that educated then shame on your for misrepresent the knowledge. There is no gene therapy whatsoever. There are no changes to human DNA either by the mRNA platforms nor the J&J
If you want to get into a pedigree argument my years in medical school residency and fellowship with active bedside treatment for twenty years as well as degrees in both biology and chemistry with emphasis on molecular biology are in every way comparable If not beyond yours. The main difference between us is that I am honest about what these vaccines are and are not. You are dishonest to serve a purpose. You have sacrificed your entire scientific pedigree on agenda. I believe that makes you a harlot.
Bureaucratic red tape. If this vaccine is good today then it was good 3 months ago. Talk to me about vaccinating people, not about approval.
I think it's claimed to be 70-80% effective after the FIRST dose. 95% after the second.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507798/
Adenovirus Vectors for Gene Therapy, Vaccination and Cancer Gene Therapy
William S.M. Wold and Karoly Toth
Additional article information
Abstract
Adenovirus vectors are the most commonly employed vector for cancer gene therapy. They are also used for gene therapy and as vaccines to express foreign antigens. Adenovirus vectors can be replication-defective; certain essential viral genes are deleted and replaced by a cassette that expresses a foreign therapeutic gene. Such vectors are used for gene therapy, as vaccines, and for cancer therapy. Replication-competent (oncolytic) vectors are employed for cancer gene therapy. Oncolytic vectors are engineered to replicate preferentially in cancer cells and to destroy cancer cells through the natural process of lytic virus replication. Many clinical trials indicate that replication-defective and replication-competent adenovirus vectors are safe and have therapeutic activity.
(Btw-baclava, why act so silly on a serious thread? Never mind, I mean that rhetorically)
Please see post 31 - then you may want to actually read up on the topic of gene therapy. Link provided.
Doctors with know-it-all syndrome, if I had a Nickle...
https://www.jwatch.org/na53085/2021/01/26/adenovirus-vectored-johnson-johnson-sars-cov-2-vaccine
In case anyone was wondering if the JnJ vaccine was really an adenovirus vector recombinant DNA vaccine. New England journal of medicine linked above.
Please make informed vaccine decisions.
These really are recombinant DNA or mRNA genetics experiments that have never been performed on human populations before.
I was talking about the mRNA vaccines which YOU said was “gene therapy”
It’s not, mRNA has nothing to do with genes, chromosomes or DNA, at all, stop spreading the lies
*For me -I like the genes I have, thank you very much. Based on an informed decision, I will pass on this genetic experiment.*
The genes you have have been altered by viruses countless times over the last 2.5 million years. Humans’ built-in susceptibility to viruses is the reason why we evolved so rapidly from our closest relatives. Our knuckles don’t drag the ground, we have larger brains, and we’re at home in water.
The only problem is the number of hominids who had to die in epidemics to make these changes possible. If you choose to pay the price of death in order to advance the species then be my guest.
Adenovirus vector- status as of 2018
My opinion- A technology that showed promise, but little to no results yet
Abstract
Adenoviruses are one of the most genetically diverse DNA viruses and cause non-life-threatening infections in the ocular, respiratory, or gastrointestinal epithelium of a diverse range of hosts. Adenoviruses are excellent vectors for delivering genes or vaccine antigens to the target host tissues and are being tested in several vaccine and gene therapy studies. Adenovirus-based vectors offer several advantages over other viral vectors such as broad range of tissue tropism, well-characterized genome, ease of genetic manipulation including acceptance of large transgene DNA insertions, inherent adjuvant properties, ability to induce robust transgene-specific T cell and antibody responses, non-replicative nature in host, and ease of production at large scale. However, several studies have highlighted major drawbacks to using adenovirus as vaccine and gene therapy vectors. These include pre-existing immunity in humans, inflammatory responses, sequestering of the vector to liver and spleen, and immunodominance of the vector genes over transgenes. In the same vein, recently discovered protein sequence homology and heterologous immunity between adenoviruses and hepatitis C virus have significant implications in the use of adenoviral vectors for vaccine development, especially for hepatitis C virus. This chapter focuses on the current scope and challenges in using adenoviral vector-based vaccines and gene therapies.
Ok - you do you, I’ll do me.
Btw - nature never used recombinant DNA in the past, but did fine tune our human genome over millions of years.
Recombinant DNA techniques and gene therapy have been around for just a tiny fraction of evolutionary time. But the techniques have the power change the course of nature dramatically, in very short time frames.
The moderna vaccine tricks human cells into producing viral protein using mRNA.
I consider that a genetics experiment. You don’t, ok...have at it.
“ There are no changes to human DNA either by the mRNA platforms nor the J&J.” Gas_dr
This is actually a very clever misrepresentation. The human dna does not change.-true
However, human cells are given viral genes (either coded in DNA in he case of adenovirus vector vaccines, or mRNA in the moderna vaccine) that are expressed in the human cells.
The key question is whose genes are being expressed in these human cells. I agree this is not a human gene. These are referred to in the literature as “trans” genes.
Pnwd
If you don’t know the relationship between mRNA and DNA, in this conversation you should probably be learning, instead of calling people names.
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