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Fountain of youth — is a fecal transplant? Procedure may turn back clock on aging brain
StudyFinds.Org ^ | 3 Octomber 2020 | Chris Melore

Posted on 10/04/2020 8:35:13 AM PDT by amorphous

NORWICH, United Kingdom — What’s the secret to eternal youth? As scientists look for ways to extend life, a new study suggests the answer to healing older brains may be hiding in younger guts. Researchers say fecal transplants not only affect your gut health, they can alter your brain too.

An international team finds fecal transplants from older to younger mice impacts the learning and memory abilities of the recipient. By altering the gut microbiome of the younger mice, researchers say they began to act more like their older donors. These changes included some of the same cognitive impairments older brains suffer from.

“Research has shown that the aging process may be linked with age-related changes in our gut microbiota,” Dr. David Vauzour from the University of East Anglia says in a release. “We wanted to see whether transferring gut microbes from older to younger mice could affect parts of the central nervous system associated with aging.” What is a fecal transplant?

Simply put, fecal transplants involve taking stool from a healthy person and placing it in the colon of someone else. In humans, the recipient is usually someone who is very sick and could have a bacterial infection.

Since the gut contains both good and bad bacteria, using antibiotics can sometimes get rid of the helpful ingredients your body needs to stay healthy. Using the bacteria from a healthy donor’s poop adds in the right materials to properly balance the human microbiome. The procedure can even help patients dealing with serious conditions like ulcerative colitis, Crohn’s disease, and cirrhosis. What does this have to do with your brain?

“Recently, the existence of two-way communication between the gut and the brain – known as the ‘gut-brain axis’ – has emerged as an important player in shaping aspects of behavior and cognitive function,” Dr. Vauzour explains.

After implanting the fecal material in younger adult mice, researchers studied how the transplant affected anxiety, exploratory behavior, and memory in each patient. The results show younger mice don’t display significant changes in terms of anxiety or behavior. They did however begin to show problems with spatial learning and memory. The young mice had trouble running through a maze test, just like older and mentally impaired mice do.

When examining this further, the team finds there are alterations in the proteins which have ties to neuro transmission. There are also changes in the cells of the hippocampus. This area of the brain forms new memories and helps control learning and emotions.

“Our research shows that a fecal transplantation from an old donor to a young recipient causes an age-associated shift in the composition of gut microbiota,” Vauzour adds. “In short, the young mice began to behave like older mice, in terms of their cognitive function.” Reversing the aging process

After proving fecal transplants can work in one direction, researchers are now looking at transplants from younger to older patients. If the procedure works in this direction, the team theorizes that the changes could reverse cognitive damage of old age.

“While it remains to be seen whether transplantation from very young donors can restore cognitive function in aged recipients, the findings demonstrate that age-related shifts in the gut microbiome can alter components of the central nervous system,” Prof. Claudio Nicoletti from the University of Florence says.

“This work highlights the importance of the gut-brain axis in aging and provides a strong rationale to devise therapies aiming to restore a young-like microbiota to improve cognitive functions and quality of life in the elderly.”

“Manipulating the microbiome is increasingly being seen as a way of improving or maintaining human health, and these results are an exciting indication of its potential for helping us age healthily” adds Prof. Arjan Narbad from the Quadram Institute.

The study appears in the journal Microbiome.


TOPICS: Health/Medicine
KEYWORDS: fecal; fountainofyouth; modernmedice; poop
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To: amorphous

"We gladly offer to assist with the transplant procedure"

21 posted on 10/04/2020 9:04:15 AM PDT by Rebelbase
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To: null and void

So...eat sh*t? Dems first. And while they’re at it, they can kiss my ass.


22 posted on 10/04/2020 9:06:07 AM PDT by DPMD
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To: amorphous

So when Swede told Sgt Highway that he was going to “Rip your head off and s*** in the hole”, Swede was really just showing concern for Highway’s health?


23 posted on 10/04/2020 9:12:22 AM PDT by Deaf Smith (When a Texan takes his chances, chances will be taken that's for sure)
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To: amorphous
Can't be.

Look how full of sh*t Biden already is.

24 posted on 10/04/2020 9:13:58 AM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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To: Deaf Smith

Southpark did a whole episode on this. Everyone wanted Tom Bradys poop


25 posted on 10/04/2020 9:14:22 AM PDT by ofcrob2237
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To: mad_as_he$$

I agree with your statement the gut and the floral which resides within the intestine are vitally essential to overall health. It’s this new brain/intestine/floral connection, which is surprising.

Like you, I see medical practitioners adding the procedure to the services they offer. Perhaps some clinics will even offer the service as the main service they provide with unique and interesting names for their businesses. :)


26 posted on 10/04/2020 9:22:06 AM PDT by amorphous
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To: silverleaf

I don’t think this has anything to do with being sh!tfaced ... or does it?


27 posted on 10/04/2020 9:26:00 AM PDT by glennaro (Democrat/Communist/Left Party core principle: You can control anyone if you frighten them enough.)
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To: ofcrob2237
Everyone wanted Tom Brady's...

One thing which comes to mind would be to preserve a child's poop, in maybe liquid nitrogen, for their own future needs (all rights reserved - butt for sale).

28 posted on 10/04/2020 9:32:24 AM PDT by amorphous
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To: curdogmen

me wife who is a retired nurse said “ when you got good sh++ you got good sh++ “ when i read the story to her


29 posted on 10/04/2020 10:00:28 AM PDT by curdogmen (we got a dog in this hunt)
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To: amorphous

Somewhere out there is a low-paid laboratory assistant whose dedication to science ended up in sticking little tubes up mice’s butts. You’d have to forgive that person wondering if Jonas Salk started out that way...


30 posted on 10/04/2020 10:07:32 AM PDT by Billthedrill
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To: amorphous

“Hey, now i remember ! That tastes like sh*T “


31 posted on 10/04/2020 10:35:21 AM PDT by drSteve78 (Je suis deplorable. WE'RE NOT GOING TO TAKE IT ANYMORE)
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To: amorphous

I’ve been doing some lactofermentation lately. It improves gut bacteria. So far, only dill pickles and sauerkraut, but I’m going to make cider vinegar, and have been culturing my own butter and sour cream.


32 posted on 10/04/2020 10:57:12 AM PDT by Flaming Conservative ((Pray without ceasing))
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To: amorphous

Why did they start old to young? Making the old young is the goal so they did the opposite? maybe hey are just milking the grant money. lol


33 posted on 10/04/2020 11:04:16 AM PDT by precisionshootist (uic)
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To: SomeCallMeTim

Some bacteria we eat does get through the stomach to the gut. So maybe eating the crusts of your kid’s sandwich might help you stay young!


34 posted on 10/04/2020 11:07:20 AM PDT by Yaelle
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To: amorphous

Let me translate “We made young mice eat 5hit from older mice and they were never the same.”


35 posted on 10/04/2020 1:43:38 PM PDT by wildcard_redneck ("Those who would give up essential Liberty, to purchase a little temporary Safety, deserve neither.")
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To: amorphous

Years ago I read that the procedure is used for extreme GERD or something similar.


36 posted on 10/04/2020 1:49:54 PM PDT by MayflowerMadam (Disappointment is inevitable. Discouragement is a choice.)
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To: amorphous

I’m currently testing one (not that company) and it works pretty well so far.


37 posted on 10/04/2020 5:03:52 PM PDT by Trillian
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To: Rebelbase

And internally check your temperature at the same time.


38 posted on 10/04/2020 5:06:40 PM PDT by Trillian
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To: Trillian
The one I posted is the one we use now, and in no way am I affiliated with this company. We switched mainly due to the claimed heat tolerance as we order through the mail, and it must sit in our rural mailbox for an extended time.

We're both believers in probiotics, especially take them if you're on antibiotics for some reason to avoid diarrhea. We like capsules because we pull one apart and get about a week's worth to give to our dog daily. As long as we give them to him, he isn't bothered by digestive issues nearly as much.

39 posted on 10/04/2020 5:16:27 PM PDT by amorphous
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To: amorphous

I had a doctor tell me that a few years ago about taking them with antibiotics. So now, when everyone’s on antibiotics or having stomach/digestive issues, we take them for a while.


40 posted on 10/04/2020 6:22:49 PM PDT by Trillian
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