Posted on 08/24/2020 3:18:56 PM PDT by Signalman
From the get go I wondered what the impact of ACE inhibitors would be. We knew early on that the virus binds to angiotensin receptors.
IIRC 6 months ago the medical scientists were saying the exact opposite.
Namely, ACE inhibitors made a person more vulnerable to a bad outcome with covid.
Anyone else remember the same????
More junk “sky-ence.”
Guess I’m good to go since I take hypertensive medication. Wanna hang out?
I take lisinopril.
That actually makes more sense.
That’s interesting. I read that some anti-hypertensives such as Lisinopril are associated with an increase in the ACE-2 receptors.
So is an increase in ACE-2 receptors a good thing or bad thing?
Of note: the university in the report is the same one that brought us Michael Mann’s climate emails scandal.
Climatic Research Unit email controversy
https://en.wikipedia.org/wiki/Climatic_Research_Unit_email_controversy
Yes, and in theory that is why the ARBs are beneficial, since they effectively bind the receptor with its ACE mate. Still open whether ACE2 inhibitors are beneficial - this mentions ACEi and ARBs.
Yes, I certainly do and animal studies were 50:50 at the time on beneficial or not. And ace inhibitors vs. ARBs.
At any rate, I am on an ARB as well as amlodipine, which is better yet (according to Chinese in vivo experience).
Simple solution to the pandemic,,,,Make HCQ and Azithromycin OTC drugs so anyone who develops a cough and/or fever can go the nearest drug store and self medicate with the drugs along with Zinc Sulfate with correct dosage within 48 hours of symptoms and pandemic over.,,,,,instead of waiting a few days to get tested and 5 days for the results,,,,if over 60 years of age,,,,you’re dead.
I asked my cardiologist about that - I'm taking an ACE inhibitor - and he told me that it's pretty well established that ACE inhibitors either protect from CoVid or make it worse. "And wouldn't it be nice if I could tell the patient which one it is?" he asked me rather sourly. He had some other stuff to say about the current state of scientific publication that I'd get banned for posting...
Let me get this straight. If I take HiBP meds, smoke and wear a mask my chances of survival are greatly improved? This is what I’ve learned in the last week.
No— the discussion by Dr. Scheulte co-founder of continuing education provider MedCram discussed medications that would aid in blocking the ACE2 receptor on lung cells.
The two discussed (two different mechanisms) were: Ace Inhibitors, and more directly blocking.... the ACE Blockers (ARBs) Losartan, Candesartan... and the other ——artan agents in the class of drugs.
All this means is, people with controlled blood pressure survive longer. Duh!
IIRC 6 months ago the medical scientists were saying the exact opposite.
Namely, ACE inhibitors made a person more vulnerable to a bad outcome with covid.
Anyone else remember the same????
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Yes, I do remember that-because my Rx was not for Ace Inhibitors and thought I was fortunate.
Yes, that’s the impression I’m getting also.
After mitral valve repair surgery (minimally invasive) ten years ago, my doctors put me on both Lisinopril and Amlodipine. My BP never really improved that much.
Then I picked up smoking again with cigars. My BP hovered around the high mark even with the meds.
Then Covid happened and I cut down smoking by 75%. I took myself off of Lisinopril after reading about ACE2 receptors early in the pandemic.
So I’m just taking amlodipine and smoking 25% of previous. My BP is the best it has ever been (120 or 130 over 70 or so) and I read that there is an An inverse relationship between smoking and COVID-19.
My head is swirling!
Also, a cholesterol med helps: fenofibrate.
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