[RummyChick]

Farid Jalali
@farid__jalali
·
34m
@cameronks

@srrezaie
I should clarify ACE expression is reduced in LUNG biopsy tissue of chronic asthmatic “human” subjects. Reduces the injurious initial unopposed surge of Ang II. https://jacionline.org/article/S0091-6749(99)70385-4/pdf

[RummyChick]

AureIien
@ValHartmann
·
4h
Replying to
@farid__jalali

@srrezaie
and 3 others
Upregulated ACE due to inhibition by the virus at ACE2 causes a multitude of detrimental effects, including hypertension, inflammation, vasoconstriction, hyglycemia, diabetes, blood coagulation, hyperaldosterone, end organ damage, autoimmune tendency.

me
@newyorker1213
·
7h
Replying to
@farid__jalali

@srrezaie
and 3 others
AGT II receptors on human platelets
https://ahajournals.org/doi/pdf/10.1161/01.RES.51.3.314
‘We conclude that human platelets possess angiotensin
receptors whose binding characteristics and modulation by dietary sodium resemble the properties
of the receptors on “classical” animal angiotensin target tissues.’