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To: RummyChick

The 1% is for homozygous people.

The 10-15% number is heterozygous.

For the latter, they aren’t immune to HIV. HOWEVER, it takes a MUCH larger initial viral load to do the trick for them.

And the time between infection and development of full blown AIDS is much longer. Ie, they’re asymptomatic spreaders MUCH longer.


369 posted on 05/06/2020 8:30:08 AM PDT by Black Agnes
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To: Black Agnes
here is another interesting thing they should look at as it wraps around to malaria..scientists could determine if sickle cell and other malaria related blood disorders provide protection. It is fascinating to see how a parasite disorder like Malaria is having an effect on an escaped lab monster

you would think blood disorder people who need tranfusions would get whacked by Wuhan Flu..but anectodotal says no



EHA and TIF explore how COVID-19 is affecting thalassemia and SCD patients

https://www.the-hospitalist.org/hospitalist/article/221017/coronavirus-updates/eha-and-tif-explore-how-covid-19-affecting

------------------

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.25840

and these people MIGHT get protection from many different things

https://www.pnas.org/content/94/26/14736.short

" This clinical study demonstrates that a malaria resistance gene protects against disease caused by infections other than malaria. The mechanism of the remarkable protective effect of α+-thalassemia against severe childhood disease remains unclear but must encompass the clear interaction between this hemoglobinopathy and both malarial and nonmalarial infections.
374 posted on 05/06/2020 8:41:56 AM PDT by RummyChick ( Yeah, it's Daily Mail. So what.)
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To: Black Agnes
"Those with two copies of the Δ32 allele in the CCR5 gene are 21 percent more likely to die by age 76, although it’s not clear why. “It is very interesting to see that the [increased mortality] effect was limited to the homozygous state,” says Hans-Peter Kiem, who studies gene therapy and transplantation at Fred Hutch, in an email. It’s possible that having one copy of the mutation offers the individual wider protection against disease than two copies of either allele and therefore may be the reason for its growing prevalence in the population."

https://www.the-scientist.com/news-opinion/genetic-mutation-that-prevents-hiv-infection-tied-to-earlier-death-65960
387 posted on 05/06/2020 8:59:27 AM PDT by RummyChick ( Yeah, it's Daily Mail. So what.)
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