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To: RummyChick

bat lady and wang LF

https://www.ncbi.nlm.nih.gov/pubmed/31996413

Discovery of Bat Coronaviruses through Surveillance and Probe Capture-Based Next-Generation Sequencing.


241 posted on 04/18/2020 7:12:57 PM PDT by RummyChick ( Yeah, it's Daily Mail. So what.)
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To: Black Agnes

you might find this interesting. Maybe you recognize the names.

Crameri(Australian Bat Man with no current internet presence)
Shi ZL (China Bat Lady now missing)
Linfa Wang( Singapore Bat Man)

https://www.ncbi.nlm.nih.gov/pubmed/20335495

Identification of key amino acid residues required for horseshoe bat angiotensin-I converting enzyme 2 to function as a receptor for severe acute respiratory syndrome coronavirus.

Abstract
Angiotensin-I converting enzyme 2 (ACE2) is the receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV). A previous study indicated that ACE2 from a horseshoe bat, the host of a highly related SARS-like coronavirus, could not function as a receptor for SARS-CoV. Here, we demonstrate that a 3 aa change from SHE (aa 40-42) to FYQ was sufficient to convert the bat ACE2 into a fully functional receptor for SARS-CoV. We further demonstrate that an ACE2 molecule from a fruit bat, which contains the FYQ motif, was able to support SARS-CoV infection, indicating a potentially much wider host range for SARS-CoV-related viruses among different bat populations.


243 posted on 04/18/2020 7:24:27 PM PDT by RummyChick ( Yeah, it's Daily Mail. So what.)
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To: RummyChick; null and void; PA Engineer; amorphous; All

I’m wondering if these were fruit bats, which if I recall are the only ones that don’t make their own Vitamin C, which if true, has interesting implications.


283 posted on 04/18/2020 10:06:51 PM PDT by gleeaikin
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