Posted on 04/14/2020 9:07:30 AM PDT by SeekAndFind
A new study from Chinese scientists on 130 recovered COVID-19 patients is raising questions about the extent to which people develop immunity to the virus.
The paper — a pre-print that has not been peer-reviewed yet — found that patients produced differing levels of antibodies . Having identifiable coronavirus antibodies in your bloodstream means you've probably built up immunity. But roughly 6% of the patients studied didn't develop any detectable antibodies at all.
"What this will mean to herd immunity will require more data from other parts of the world," Huang Jinghe, the leader of the research team behind the report, said, according to the South China Morning Post.
Interestingly, the levels of antibodies patients produced seemed to correlate with their ages: Middle-aged and elderly recovered patients had higher levels of antibodies. Nine of the 10 of the patients who did not develop detectable levels of coronavirus antibodies were 40 years old or younger.
Finding out more about how antibodies to the virus work will have major implications for both vaccine development and the potential for herd immunity.
The study, from researchers from Fudan University in Shanghai, took blood samples from 175 coronavirus patients who had recovered at Shanghai hospitals and who'd had "mild" symptoms. (Patients with "severe" symptoms were excluded because many had received blood transfusions to treat their illnesses.)
The participants ranged in age from 16 to 68, and the scientists grouped them into three categories: elderly (60-85), middle-aged (40-59), and young (15-39).
They found that the patients developed antibodies around 10 to 15 days after the disease's onset and remained stable afterwards.
The researchers measured the levels of neutralizing antibodies (NAbs) in each patient's blood, and found that recovered elderly patients developed significantly higher levels of antibodies than younger patients did.
(Excerpt) Read more at businessinsider.com ...
https://twitter.com/trvrb/status/1249414295042965504
That’s a good thread about testing prior samples from January on and what they found.
Wow could it be that the diagnosis was wrong. Oh horrors.
Thanks
Yes, but some reports suggest that even those antibodies only last a few months. That you don’t get a lifetime immunity.
Bio Weapons can be really nasty.
"By the summer of 1919, the flu pandemic came to an end, as those that were infected either died or developed immunity.
Almost 90 years later, in 2008, researchers announced they’d discovered what made the 1918 flu so deadly: A group of three genes enabled the virus to weaken a victim’s bronchial tubes and lungs and clear the way for bacterial pneumonia.
Since 1918, there have been several other influenza pandemics, although none as deadly. A flu pandemic from 1957 to 1958 killed around 2 million people worldwide, including some 70,000 people in the United States, and a pandemic from 1968 to 1969 killed approximately 1 million people, including some 34,000 Americans."
Notice the time span of these previous 'pandemics'... Roughly a year... This one will be no different... Except for one thing... We have destroyed our economy to fight this flu... And thousands will likely die from a variety of conditions brought on by poverty. Social platforms on the internet and a misguided media have led us into creating a 'great depression' that will likely damage an entire generation of people for decades to come.
I have seasonal allergies. So, is my coughing and sneezing, which is similar to the last few decades, due to seasonal allergies or to the Wuhan bat coronavirus?
Most everything shut down in 2020 was also shut down in 1918. Churches, restaurants, public meeting places, you name it.
It DID cause a mini depression.
Then the recovery was the ‘roaring 20’s’.
We need to change the tax laws and allow businesses to amass cash reserves that aren’t penalized. Ditto inventory. We hamstring our businesses ability to withstand unexpected events with our tax laws.
Maybe you’re allergic to bats?
Does it produce the Hershey squirts?
I believe I am immune to the flu. All strains. I cannot remember one time in my life, ever, when I had the flu.
Once my wife, son, and brother-in-law all had it . . . but I didn’t.
I have seasonal allergies. So, is my coughing and sneezing, which is similar to the last few decades, due to seasonal allergies or to the Wuhan bat coronavirus?”
I have had my seasonal sinus infection. I’m sure it is not Wuhan as I have had no loss of smell or loss of appetite.
For your friend the immunology prof:
If the antibody levels with this are so low, how is it causing cytokine storms which ultimately kill the patient? The two things would seem to contradict one another.
That’s not a smart-alecky question, I’m genuinely curious.
No idea. She’s not a clinician. She teaches immunology and I think still does a bit of research, but after her post doc work teaching became her focus.
She isn’t going to know about disease progression. Just antibodies and Memory B cells and T lymphocytes. BTW she did say antibodies often are not what cures a patient. The rest of the immune system is activated by them. White cells actually do the removal of infection, signaled by antibody presence.
Oh and she also said it’s common to get antibodies produced that do not just signal presence of virus. They will attach to cells the virus has infected, before they burst, and white cells come and remove those cells.
Hard to predict what a Chinese made biological weapon will do. They probably didn’t know. Oh, I forgot, it was bat wing soup.
Restaurants? We’re talking 1918/19... There may have been restaurants in some places, but most people couldn’t afford take out back then. The ‘Roaring 20’s’ were a result of jobs created by the war effort back in America, they were not a result of the Spanish Flu.
Most cities had restaurants.
Also churches, movies and other public entertainments.
All were shut down.
Ditto schools.
Things didn’t start picking back up until 1920 or later, WELL after WWI at that point.
Lots of historical articles here:
https://quod.lib.umich.edu/f/flu/browse/titles/c.html
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