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To: PA Engineer
Does Covid-19 infect the brain like SARS?

The infection of SARS-CoV has been reported in the brains from both patients and experimental animals, where the brainstem was heavily infected. Furthermore, some coronaviruses have been demonstrated able to spread via a synapse-connected route to the medullary cardiorespiratory center from the mechano- and chemoreceptors in the lung and lower respiratory airways. In light of the high similarity between SARS-CoV and SARS-CoV2, it is quite likely that the potential invasion of SARS-CoV2 is partially responsible for the acute respiratory failure of COVID-19 patients.

https://www.ncbi.nlm.nih.gov/pubmed/32104915

601 posted on 03/02/2020 10:18:00 PM PST by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86

So pneumonia and cytokine storms might be an only partial explanation for respirtory failure.


604 posted on 03/02/2020 10:19:45 PM PST by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86

Somebody tell the “it’s just a head cold” or “same as the flu” trolls about the brain stem infection findings.


613 posted on 03/02/2020 10:28:35 PM PST by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86
coronaviruses have been demonstrated able to spread via a synapse-connected route to the medullary cardiorespiratory center from the mechano- and chemoreceptors in the lung

Could flooding the lungs with fluid disable these "mechano- and chemoreceptors in the lung", and that alone interrupts the breathing reflex? Or are they claiming, or suspecting, that the infection that somehow reached the brain stops the breathing reflex?

Reminds me of the stories of birds dropping out of the sky, suddenly dead. I guess that's what has happened to some in China ... people just suddenly drop dead.

616 posted on 03/02/2020 10:33:34 PM PST by Tellurian (DeMullahkRats would smugly tell even God "you didn't build that".)
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To: steve86
Thank you.

Complete article from Sci-Hub: The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients

I'm reading it now and have some doubts. Mouse models of protein expression are very different than those of humans. Protein Atlas ACE2 Brain Expression.

Possibly there may be a breakdown in the blood brain barrier that will result in some to be more vulnerable than others.

It would be nice to see a simple clinical neuro-examination of patients as well as saliva miRNA protein expression.

Thank you again.
619 posted on 03/02/2020 10:43:34 PM PST by PA Engineer (Liberate America from the Occupation Media.)
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