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Scientists have successfully cured diabetes in mice for the first time, giving hope to millions worldwide
indy100.com ^ | February 29, 2020 | Louis Staples

Posted on 02/29/2020 3:12:14 PM PST by Berlin_Freeper

Diabetes is a disease that has a huge impact on peoples’ lives.

So far the disease, which is thought to affect over 400 million people worldwide, is understood to be incurable. But researchers at the Washington University School of Medicine in St Louis have just proved that it is possible to cure diabetes in mice in just a couple of weeks.

IFL Science’s Alfredo Carpineti reports that the researchers used human cells to keep the disease at bay for at least nine months and up to more than a year in some mice. The findings were published in Nature Biotechnology.

(Excerpt) Read more at . ...


TOPICS: Health/Medicine
KEYWORDS: diabetes
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1 posted on 02/29/2020 3:12:14 PM PST by Berlin_Freeper
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To: Berlin_Freeper

Scientists have also cured cancer in mice.

Good news... if you’re a mouse.


2 posted on 02/29/2020 3:14:09 PM PST by SeekAndFind (look at Michigan, it will)
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To: Berlin_Freeper

In before the Eeyores.


3 posted on 02/29/2020 3:14:14 PM PST by Magic Fingers (Political correctness mutates in order to remain virulent.)
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To: Magic Fingers

Too late.


4 posted on 02/29/2020 3:14:28 PM PST by Magic Fingers (Political correctness mutates in order to remain virulent.)
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To: Berlin_Freeper

BTW, the link you provided is bad.


5 posted on 02/29/2020 3:14:47 PM PST by SeekAndFind (look at Michigan, it will)
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To: Berlin_Freeper

Here is the correct link to the article:

https://www.indy100.com/article/diabetes-cure-science-mice-human-cells-9366381


6 posted on 02/29/2020 3:15:50 PM PST by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

https://www.indy100.com/article/diabetes-cure-science-mice-human-cells-9366381


7 posted on 02/29/2020 3:16:21 PM PST by Berlin_Freeper
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To: Berlin_Freeper; SeekAndFind

8 posted on 02/29/2020 3:19:07 PM PST by DannyTN
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To: Berlin_Freeper
Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells
9 posted on 02/29/2020 3:24:01 PM PST by Berlin_Freeper
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To: Berlin_Freeper

Again, the cute little rodents get cured first. PDJT should do something about this species discrimination in our health system.


10 posted on 02/29/2020 3:24:41 PM PST by faithhopecharity ( “Politicians are not born; they are excreted.” Marcus Tullius Cicero (106 to 43 BCE).)
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To: Berlin_Freeper

Wilford is not amused!

11 posted on 02/29/2020 3:24:48 PM PST by dfwgator (Endut! Hoch Hech!)
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To: SeekAndFind

“Good news... if you’re a mouse.”

Especially insulin-dependent ones.


12 posted on 02/29/2020 3:24:50 PM PST by LouieFisk
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To: Berlin_Freeper
Generation of pancreatic β cells from human pluripotent stem cells (hPSCs) holds promise as a cell replacement therapy for diabetes. In this study, we establish a link between the state of the actin cytoskeleton and the expression of pancreatic tran-scription factors that drive pancreatic lineage specification. Bulk and single-cell RNA sequencing demonstrated that different degrees of actin polymerization biased cells toward various endodermal lineages and that conditions favoring a polymerized cytoskeleton strongly inhibited neurogenin 3-induced endocrine differentiation. Using latrunculin A to depolymerize the cyto-skeleton during endocrine induction, we developed a two-dimensional differentiation protocol for generating human pluripo-tent stem-cell-derived β (SC-β) cells with improved invitro and invivo function. SC-β cells differentiated from four hPSC lines exhibited first- and second-phase dynamic glucose-stimulated insulin secretion. Transplantation of islet-sized aggregates of these cells rapidly reversed severe preexisting diabetes in mice at a rate close to that of human islets and maintained normo-glycemia for at least 9 months.

13 posted on 02/29/2020 3:26:28 PM PST by Berlin_Freeper
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To: Berlin_Freeper

The mouse stopped smoking lost a bunch of weight?


14 posted on 02/29/2020 3:28:39 PM PST by 2banana (My common ground with islamic terrorists - they want to die for allah and we want to kill them.)
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To: Berlin_Freeper
The article doesn't make these clear but the paper appears to be talking about Type I, which is an inability to secrete sufficient insulin, not Type II which is an insensitivity to insulin.

That's good, because Type I can't be fixed with diet.

15 posted on 02/29/2020 3:30:09 PM PST by mlo
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To: SeekAndFind
Good news... if you’re a mouse.

...and you have insurance!

16 posted on 02/29/2020 3:30:09 PM PST by null and void (By the pricking of my lungs, Something wicked this way comes ...)
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To: Berlin_Freeper

Let me guess, they fed them a low carb diet.


17 posted on 02/29/2020 3:36:09 PM PST by Brookhaven (If CNN is playing, ask them to change the channel. #ChangeCNN)
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To: Berlin_Freeper

Scientists have successfully cured diabetes in mice for the first time, giving hope to millions of mice worldwide


18 posted on 02/29/2020 3:38:55 PM PST by minnesota_bound (homeless guy. He just has more money....He the master will plant more cotton for the democrat party)
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To: minnesota_bound

Humans a really nothing more than servants for cats and mice.


19 posted on 02/29/2020 3:41:43 PM PST by Moonman62 (Charity comes from wealth.)
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To: Berlin_Freeper

Which diabetes? There are at least 2.


20 posted on 02/29/2020 3:47:50 PM PST by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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