[HangnJudge]

Today’s lesson

XX, XXX, XO..... Female
XY, XXY, XYY.... Male
Smattering of minor variants
Androgen insensitivity syndrome
Various Hermaphrodites

All the other stuff is cognitive constructs
Or Med/Surg monsters

[originalbuckeye]

Doesn’t matter what any guy tries......every cell in his body will ALWAYS have a Y chromosome (except about half of his sperm, which will only have one chromosome [normally] an X or a Y).

[chesley]

I got the X. I got the Y. What does the O stand for? Regular non-X, non-Y chromosome?

[Jewbacca]

I have a friend who is XYY.

The tallest, strongest, hairiest dude I’ve ever met.

Brilliant doctor, but looks like a missing link.

[JohnBovenmyer]

Complete Androgen Insensitivity is the major problematic one as there is no current treatment for it turning an otherwise normal male embryo into a facsimile of a female. It often isn't detected until puberty fails to arrive, giving quite a shock. It occurs roughly in 5/100,000 chromosomally male births.

The other major, potentially significant one is Congenital Adrenal Hyperplasia, about 7/100,000 chromosomally female births, which in severe forms can make a girl into a male facsimile. It presents early in life and in US is included in neonatal blood screens. Usually more than just sex hormones are affected, with significant other consequences, so it should be treated and can be at least partially corrected. Prenatal diagnosis and treatment is possible and probably would minimize its genital abnormalities. Liberal 'thinkers' react insanely and argue against its treatment! You'd think learning their baby daughter was suffering from the worst testosterone poisoning known to mankind would have them eager to fix it.