This researcher sums up a lot of knowledge into one concise scientific paper on reducing the effects of aging on each of us.
Navigation: use the links below to view more comments.
first 1-20, 21-40, 41-50 next last
To: ConservativeMind
To: ConservativeMind
To: ConservativeMind
To: ConservativeMind
5 posted on
07/27/2019 8:17:42 PM PDT by
wjcsux
(The hyperventilating of the left means we are winning! (Tagline courtesy of Laz.))
To: ConservativeMind
Can you summarize this in a 5 sentence paragraph.
6 posted on
07/27/2019 8:17:49 PM PDT by
CaptainK
('No collusion, no obstruction, he's a leaker')
To: ConservativeMind
it costs very little each day cover the bases with a Pharmacy Grade (NOT FOOD GRADE!) MultiVit and a few others (I do Omegas and Magnesium, then eat spinach and nuts an oats and fruit and meats and other stuff like that as much as possible.)
Very easy, very inexpensive. Even if you eat lots of crap, you can at least supplement the crap by making sure you also cover the bases.
Or ... go ahead and die early! Woohoo!
8 posted on
07/27/2019 8:23:34 PM PDT by
tinyowl
(A is A)
To: ConservativeMind
PS thanks for posting ... I admittedly skimmed some sections but read all of the important stuff. It surprises me that people don’t pay more attention to this stuff. I get it, it can be boring, but there’s nothing boring about living an extra 20 years, with a happy healthy body. You can’t guarantee it, but you can probably do enough that in most cases you buy yourself a hell of a lot of extra years not to mention feel way better each moment today.
12 posted on
07/27/2019 8:27:35 PM PDT by
tinyowl
(A is A)
To: ConservativeMind
Bookmarked under Health. Vitamins
13 posted on
07/27/2019 8:28:38 PM PDT by
goodnesswins
(White Privilege EQUALS Self Control & working 50-80 hrs/wk for 40 years!)
To: ConservativeMind
Ummmm....
Keto diet and Intermittent Fasting....
And Bone Broth....
Lions Maine Mushrooms
You are welcome.
15 posted on
07/27/2019 8:31:10 PM PDT by
Jayster
To: ConservativeMind
16 posted on
07/27/2019 8:32:36 PM PDT by
Old Yeller
(Auto-correct has beco</me my worst enema.)
To: ConservativeMind
19 posted on
07/27/2019 8:40:38 PM PDT by
BunnySlippers
(I Love Bull Markets!)
To: ConservativeMind
I wonder how much genetics have to do with how you age. My dad has a completely unscientific theory: when a person is develops slowly, they age slowly as well. He was a “late bloomer” but has always looked younger than he was. My mom looks young for her age as well.
He thinks that some people just mature/age more slowly than others. Perhaps some are genetically wired to have telomeres that shorten more slowly than others.
To: ConservativeMind
24 posted on
07/27/2019 9:06:04 PM PDT by
leaning conservative
(snow coming, school cancelled, yayyyyyyyyy!!!!!!!!!!!)
To: ConservativeMind
Excellent, thanks.
I also suggest reading Wheat Belly, by William Davis, MD. and Grain Brain, by David Perlmutter, MD:
https://www.drperlmutter.com/about/grain-brain-by-david-perlmutter/
Perlmutter has a new book coming next year describing a somewhat different approach. He suggests eating only 2x per day, about 11:00 a.m. and 5 P.M, with protein at the evening meal because it takes 15 hours to completely absorb.
This is exactly what I’ve been doing for years, decades maybe. Have zero interest in food in the morning.
I took your article, transported it to Word and increased the type size so I can actually read it.
27 posted on
07/27/2019 9:21:20 PM PDT by
Veto!
(Veto! (Political Correctness Offends Me))
To: ConservativeMind
Thank you. Very helpful. Conclusion of author:
“I propose that an optimal level of many of the known 30 vitamins and essential minerals is necessary for promoting healthy aging.”
If a person wishes to live in a healthy way for many years, then he should review the 30 vitamins and minerals in the article.
2 of the 30 above include Vitamin D and Magnesium Citrate. Both are highly recommended by Dr. D. Eames and fitness pro F. Hahn.
Try different brands until you find one that does not make you tired. I personally like Nature’s Way brand. Sure, vitamins can be a waste of money. No need to take them every day. Once a week is fine. But certainly get D and Magnesium: two main ones.
To: ConservativeMind
Most of us are unwilling to wade through all of that, even if our lives depend on it...
30 posted on
07/27/2019 9:31:04 PM PDT by
null and void
(The Left isn't banning "Hate Speech", they are banning speech they hate. BIG difference.)
To: ConservativeMind
It's a lot clearer with the footnotes
↵
32 posted on
07/27/2019 9:37:22 PM PDT by
null and void
(The Left isn't banning "Hate Speech", they are banning speech they hate. BIG difference.)
To: ConservativeMind
35 posted on
07/27/2019 9:52:08 PM PDT by
aquila48
To: ConservativeMind
Reference/health bump - waiting for executive summary bump!
37 posted on
07/27/2019 9:59:08 PM PDT by
Tunehead54
(Nothing funny here ;-)
To: ConservativeMind
Thanks for the post and link. This is a good review.
I am going to present four abstracts at the Movements Disorders meeting in Nice this fall. We have been investigating neurodegeneration involving disregulation of the Cupin superfamily and the metabolic "cycle" involved in human health and aging.
Taurine is a major end product in both the exogenous and endogenous pathways. The author was somewhat correct on the pathways to taurine.
We have focused deeply on these pathways because of a rare gene mutation that attacks children. During the research we realized that the disorder was the Rosetta Stone for neurodegeneration.
Taurine deficiency is a serious problem in human aging as well as numerous diseases, however the upstream metabolites that convert to taurine are far more critical for the prevention of neurodegeneration. These are cysteamine and hypotaurine. Hypotaurine is produced from two different dioxygenase pathways to taurine. One is cysteine and the other cysteamine. Both cysteramine and hypotaurine are necessary reactive oxygen species scavengers in the brain, whereas taurine is not.
The cysteamine part of the cycle is the endogenous portion from the breakdown of coenzyme A. This is being researched now in Parkinson's and Huntington's disease. The initial Huntington's RCT failed to show disease reversal, however it was too short. It did show a dramatic increase in brain derived neurotrophic factor (BDNF). This was probably the most important finding.
The cysteine portion is more of an exogenous pathway to hypotaurine and taurine. Cysteine can be increased by dietary intake such as eggs or by supplement with NAC.
We have found an older metabolite that fulfills the endogenous part of the cycle. This is Pantethine and has been researched for almost 60 years (well over 600 papers and hundreds of RCTs). It was the frontline hypercholesterolemia agent prior to statins. Further, pantethine lowered LDL, raised HDL, lowered triglycerides and improved platelet clotting function. It did not lower LDL as much as statins. That was the marketing appeal of statins. Unlike statins, Pantethine's action did not involve the disruption of the mevalonate pathway. Pantethine breaks down after oral ingestion in the lumina of the intestine to pantothenate and cysteamine. Cysteamine is the critical agent to support the endogenous portion of the hypotaurine to taurine pathway. Both cysteamine and pantethine have shown other therapeutic benefits including protection in malaria infection, radiation treatment and brain infarct.
Sadly, because of statin marketing, pantethine research has slowed dramatically in the past 15 years. This is tragic for those suffering from metabolic disorders and those who are also taking statins. I will go on record as saying when the time comes, statins will be seen as the worse of bad drugs. The controversy over Vioxx and Tamiflu will pale in comparison. The first lawsuits have already been filed over statin caused type 2 diabetes. The longterm neurological damage has yet to be assessed.
I am not a doctor and this is not medical advice. Pantethine can be found on Amazon (active agent Pantesin). My wife and I began taking it three years ago at a dose of 450mg TID.
I'll be able to post much more after the meeting and also our submissions of other IRBs and NIH R01 applications.
For those who are interested in problems with disrupting the mevalonate pathway there is this link:
Statin Damage to the Mevalonate Pathway.
39 posted on
07/27/2019 10:12:03 PM PDT by
PA Engineer
(Liberate America from the Occupation Media.)
Navigation: use the links below to view more comments.
first 1-20, 21-40, 41-50 next last
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson