***belladonna dilates the pupils hugely***
Belladonna used to be in Contact cold medicine; you remember Contact, the cold med that really worked! They discovered that it caused heart problems in .0000034 % of its users, so naturally had to remove it from the market.
A pharmacist friend of mine gave me a bottle of the extract, USP, which I surely needed in those days. I can't remember my eyes getting any bigger, however
My late mother once told me that she knew of women, in the 1930s, using belladonna as an eye dilator in order to enhance their looks.