Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Hundreds of genes seen sparking to life two days after death
New Scientist ^ | 21 June 2016 | Anna Williams

Posted on 06/22/2016 10:46:20 AM PDT by Theoria

The discovery that many genes are still working up to 48 hours after death has implications for organ transplants, forensics and our very definition of death

When a doctor declares a person dead, some of their body may still be alive and kicking – at least for a day or two. New evidence in animals suggests that many genes go on working for up to 48 hours after the lights have gone out.

This hustle and bustle has been seen in mice and zebrafish, but there are hints that genes are also active for some time in deceased humans. This discovery could have implications for the safety of organ transplants as well as help pathologists pinpoint a time of death more precisely, perhaps to within minutes of the event.

Peter Noble and Alex Pozhitkov at the University of Washington, Seattle, and their colleagues investigated the activity of genes in the organs of mice and zebrafish immediately after death. They did this by measuring the amount of messenger RNA present. An increase in this mRNA – which genes use to tell cells to make products such as proteins – indicates that genes are more active.

Noble’s team measured mRNA levels in zebrafish, and in brain and liver samples from mice at regular intervals for up to four days after death. They then compared these with mRNA levels measured at the time of death.

As you might expect, overall mRNA levels decreased over time. However, mRNA associated with 548 zebrafish genes and 515 mouse genes saw one or more peaks of activity after death. This meant there was sufficient energy and cellular function for some genes to be switched on and stay active long after the animal died.

(Excerpt) Read more at newscientist.com ...


TOPICS: Science
KEYWORDS: death; dna; genes; mrna
Navigation: use the links below to view more comments.
first previous 1-2021-25 last
To: mumblypeg

“corpses burp and fart all the time”

On TV they walk. In the real world, they’re just The Farting Dead. Why does reality always have to be so bland compared to fiction? It’s seriously disillusioning.


21 posted on 06/22/2016 12:07:54 PM PDT by bluejean (The lunatics are running the asylum)
[ Post Reply | Private Reply | To 16 | View Replies]

To: Theoria

“...probably pining for the fjords...”


22 posted on 06/22/2016 1:06:54 PM PDT by Prov1322 (Enjoy my wife's incredible artwork at www.watercolorARTwork.com! (This space no longer for rent))
[ Post Reply | Private Reply | To 1 | View Replies]

To: factoryrat

Hair and nails keep growing.


23 posted on 06/22/2016 5:12:37 PM PDT by Secret Agent Man (Gone Galt; Not averse to Going Bronson.)
[ Post Reply | Private Reply | To 9 | View Replies]

To: Secret Agent Man
They seem to but the flesh is receding as the body decomposes, hair and nails appear to be growing..
24 posted on 06/22/2016 11:41:48 PM PDT by goat granny
[ Post Reply | Private Reply | To 23 | View Replies]

To: Theoria

Yes, thank you for posting this!


25 posted on 06/22/2016 11:45:55 PM PDT by kalee
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-25 last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson