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Red wine: Exercise in a bottle?
Federation of American Societies for Experimental Biology ^ | 30-Jun-2011 | Gerald Weissmann, M.D.

Posted on 06/30/2011 10:15:18 AM PDT by Pharmboy

New research in the FASEB Journal suggests that a daily intake of resveratrol prevents the ill effects of simulated weightlessness on muscle and bone metabolism Bethesda, MD—As strange as it sounds, a new research study published in the FASEB Journal (http://www.fasebj.org), suggests that the "healthy" ingredient in red wine, resveratrol, may prevent the negative effects that spaceflight and sedentary lifestyles have on people. The report describes experiments in rats that simulated the weightlessness of spaceflight, during which the group fed resveratrol did not develop insulin resistance or a loss of bone mineral density, as did those who were not fed resveratrol.

According to Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal, "There are overwhelming data showing that the human body needs physical activity, but for some of us, getting that activity isn't easy. A low gravity environment makes it nearly impossible for astronauts. For the earthbound, barriers to physical activity are equally challenging, whether they be disease, injury, or a desk job. Resveratrol may not be a substitute for exercise, but it could slow deterioration until someone can get moving again."

Scientists studied rats that underwent simulated weightlessness by hindlimb tail suspension and were given a daily oral load of resveratrol. The control group showed a decrease in soleus muscle mass and strength, the development of insulin resistance, and a loss of bone mineral density and resistance to breakage. The group receiving resveratrol showed none of these complications. Study results further demonstrated some of the underlying mechanisms by which resveratrol acts to prevent the wasting adaptations to disuse-induced mechanical unloading. This study also suggests that resveratrol may be able to prevent the deleterious consequences of sedentary behaviors in humans.

"If resveratrol supplements are not your cup of tea," Weissmann added, "then there's good news. You can find it naturally in red wine, making it the toast of the Milky Way."


TOPICS: Health/Medicine
KEYWORDS: faseb; oenology; redwine; resveratrol; wine
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Just a cautionary note: resveratrol is very poorly absorbed, so supplements do not get the blood levels up very much, and neither does red wine. The pharmaceutical industry has been working on molecular forms which are more readily absorbable.
1 posted on 06/30/2011 10:15:23 AM PDT by Pharmboy
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To: neverdem; thefactor; SunkenCiv; Dr. Scarpetta; aculeus
Ping

I like Glenlivet myself...

2 posted on 06/30/2011 10:17:49 AM PDT by Pharmboy (What always made the state a hell has been that man tried to make it heaven-Hoelderlin)
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To: Pharmboy
Amen brother. Single malt is the only way to fly.


3 posted on 06/30/2011 10:20:49 AM PDT by Lazlo in PA (Now living in a newly minted Red State.)
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To: Pharmboy; derllak
So, does this mean we have to drink a whole lot of it to absorb the good stuff?

:-)

4 posted on 06/30/2011 10:21:34 AM PDT by Lakeshark (Thank a member of the US armed forces for their sacrifice)
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To: Pharmboy

Beer has done a good job of keeping me from suffering from weightlesness


5 posted on 06/30/2011 10:22:09 AM PDT by CrazyIvan (Obama's birth certificate was found stapled to Soros's receipt.)
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To: Pharmboy

Think I’ll go drink me a marathon.


6 posted on 06/30/2011 10:22:30 AM PDT by dfwgator
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To: Pharmboy
Sheeesh...poor cold water on good news (which we get little enough of these days as it is).

Just go with it, man...after a bit you won't even care about absorption. ;-)

7 posted on 06/30/2011 10:24:04 AM PDT by Scott from the Left Coast
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To: Lakeshark

I’ll drink to that!

I’m hoping cheetos will have the same effect.


8 posted on 06/30/2011 10:25:37 AM PDT by derllak
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To: Pharmboy

Red wine is more like ‘headache in a bottle’ for me. Migraine city.


9 posted on 06/30/2011 10:25:54 AM PDT by The Iceman Cometh (I'm called a 'teabagger'? Well, get over here liberal and I'll show you what that means.)
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To: derllak
Pita chips have that affect.

They listen well too........

10 posted on 06/30/2011 10:27:13 AM PDT by Lakeshark (Thank a member of the US armed forces for their sacrifice)
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To: All

b


11 posted on 06/30/2011 10:28:01 AM PDT by Maverick68
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To: Lakeshark

Lol!

Talking to your pita chips probably means you’ve had enough. :P


12 posted on 06/30/2011 10:30:55 AM PDT by derllak
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To: Pharmboy

And one, and two, and three...

13 posted on 06/30/2011 10:31:05 AM PDT by stormer
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To: derllak

Likewise, talking to your bottle of red wine.....


14 posted on 06/30/2011 10:32:20 AM PDT by Lakeshark (Thank a member of the US armed forces for their sacrifice)
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To: All

Ha! Some great ones, folks...chuckling at office.


15 posted on 06/30/2011 10:36:10 AM PDT by Pharmboy (What always made the state a hell has been that man tried to make it heaven-Hoelderlin)
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To: The Iceman Cometh
Indeed...not a rare phenomenon at all (my wife has this, but reds don't bother me when I do drink them). Try this site for some answers.
16 posted on 06/30/2011 10:39:29 AM PDT by Pharmboy (What always made the state a hell has been that man tried to make it heaven-Hoelderlin)
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To: Pharmboy

So I guess when I tell people that I’m spending all weekend at the gym I won’t REALLY be lieing.


17 posted on 06/30/2011 10:42:21 AM PDT by thefactor (yes, as a matter of fact, i DID only read the excerpt)
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To: The Iceman Cometh

“Migraine City”

Me too! Even a half a glass gives me a migraine.


18 posted on 06/30/2011 10:43:04 AM PDT by momtothree
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To: Pharmboy

If the wine does not deliver enough resveratrol to increase blood levels, then what is the explanation for the apparent positive clinical effects red wine has in humans?


19 posted on 06/30/2011 10:48:44 AM PDT by ottbmare (off-the-track Thoroughbred mare)
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To: Pharmboy; Lazlo in PA
BTW, here's an article about Glenmorangie's new offering. It's a single malt that was made in 1981 and aged for almost 29 years. It's called 'Pride' and it costs $3,600 a bottle. Only 1,000 bottles produced. Crystal bottle, wooden case, etc...

http://www.cigaraficionado.com/webfeatures/show/id/15916

20 posted on 06/30/2011 10:49:04 AM PDT by thefactor (yes, as a matter of fact, i DID only read the excerpt)
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