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FR Folding@Home Project- ATI Stream Computing Drive Bio-Medical Research at Stanford University
ATI Website and Stanford University ^ | Nov 13 2006 | Vijay Pande

Posted on 11/21/2006 8:07:23 PM PST by texas booster

Today ATI's graphics processors help accelerate complex computations in stream computing applications used in scientific research. ATI is supporting bio-medical research to help scientists understand disease at the genetic level. With a strong understanding of how diseases form, it will become possible to develop diagnostic methods, and preventative treatment and medicine for many acute diseases in humans.

Stanford University is using ATI’s GPUs (Graphics Processor Units) to run Folding@Home, a distributed computing project designed by its chemistry department. This application performs computationally intensive simulations of protein folding, using the stream computing capabilities of ATI’s Radeon® 1900 and 1950 Series processors, which provide incremental power over CPU processing. ATI’s Radeon® X1900 and Radeon® X1950 Series process the complex calculations of the simulation and render advanced 3D visualization of the protein folding process in real time.

Folding@Home will help researchers uncover how certain diseases develop, including:

Cancer

Alzheimer's Disease

Parkinson's Disease

Huntington's Disease

Osteogenesis Imperfecta

Stanford University’s research team discovered that ATI’s Radeon X1900 and Radeon X1950 Series of products provide 20 to 40 times faster processing over CPUs in many of the calculations needed to simulate the folding of proteins.

What is Protein Folding Proteins are necklaces of amino acids – long chain molecules that drive all biochemical reactions in the human body, helping to build bones, muscles and blood vessels, and helping the body fight infections. To accomplish these tasks, proteins must take on a particular shape, or, to “fold”. Proteins that fold incorrectly can cause complications and can lead to critical diseases. Folding@Home simulates the folding process to understand why proteins don’t fold correctly. The findings will help researchers prevent and cure these diseases.

You Can Help Find the Cure Folding@home uses distributed computing to simulate protein folding – instead of using super computers, the workload is broken up into small work units and distributed across 100,000’s of PC systems over the internet. When users throughout the world download and run the application they directly contribute to a good cause through the power of their ATI graphics processor. The GPU version of the application will use the processing power of end users’ GPUs to accelerate the simulation and provide data to Stanford’s researchers faster.

Every new PC that runs the application gets us closer to the cure.

You can help by simply downloading and running the Folding@Home application developed by Stanford University. The application is free and secure. It will run in the background, making use of spare GPU capacity in your PC, without impacting the performance of your other applications.

You can increase your contribution by forming and joining teams and competing against others. Contributors are assigned a score indicating the number and difficulty of completed work units. Rankings and other statistics are posted to the Folding@Home website.

Please note that, currently, only the following products in ATI’s Radeon X1900 Series and Radeon X1950 Series can run the application. We will post information about upcoming products that will support this application in the near future.

Radeon X1900 Series: Radeon X1900 GT, Radeon X1900 XT, Radeon X1900 XTX, Radeon X1900 CrossFire Edition

Radeon X1950 Series: Radeon X1950 XTX, Radeon X1950 CrossFire Edition


TOPICS: Health/Medicine
KEYWORDS: ati; fh
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To: processing please hold

If you two instances are running then we can just leave them alone.

The set advanced methods should be set during installation. I am a little concerned that you did not set the machineid= 1 or 2.

Let it run overnight. Then look at in each folder at the "unitinfo.txt" file. That will tell you what you are running and what the progress is.


81 posted on 11/30/2006 5:32:02 PM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster
The set advanced methods should be set during installation. I am a little concerned that you did not set the machineid= 1 or 2.

I didn't. I hit the download and it didn't ask anything of me when it said files downloaded. Can I just get rid of it and start from scratch?

82 posted on 11/30/2006 5:38:30 PM PST by processing please hold
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To: processing please hold

Note: Please read the license agreement (FAH504-Console.exe -license). Further
use of this software requires that you have read and accepted this agreement.


The file FAHlog.txt has been locked by the operating system and cannot be
opened for writing (possibly because it is open in another application).
Before you next run F@H, please ensure FAHlog.txt is not open anywhere,
or simply delete it. For now, FAHlog2.txt will be used.


--- Opening Log file [December 1 01:39:12]


# Windows Console Edition #####################################################
###############################################################################

Folding@Home Client Version 5.04beta

http://folding.stanford.edu

###############################################################################
###############################################################################

Launch directory: C:\Program Files\Folding@Home
Executable: C:\Program Files\F@H1\FAH504-Console.exe


[01:39:12] - Ask before connecting: No
[01:39:12] - User name: pbrown (Team 36120)
[01:39:12] - User ID: 499E21481F205083
[01:39:12] - Machine ID: 1
[01:39:12]
[01:39:12] Loaded queue successfully.
[01:39:12] + Benchmarking ...
[01:39:15]
[01:39:15] + Processing work unit
[01:39:15] Core required: FahCore_78.exe
[01:39:15] Core found.
[01:39:15] Working on Unit 01 [December 1 01:39:15]
[01:39:15] + Working ...
[01:39:15]
[01:39:15]



[01:39:15] Folding@Home Gromacs Core
[01:39:15] Version 1.90 (March 8, 2006)
[01:39:15]
[01:39:15] Preparing to commence simulation
[01:39:15] - Looking at optimizations...
[01:39:15] - Files status OK
[01:39:15] - Expanded 78912 -> 420497 (decompressed 532.8 percent)
[01:39:15]
[01:39:15] Project: 2124 (Run 58, Clone 34, Gen 5)
[01:39:15]
[01:39:15] Assembly optimizations on if available.
[01:39:15] Entering M.D.
[01:39:36] (Starting from checkpoint)
[01:39:36] Protein: p2124_lambda_5way_melt_4_10011
[01:39:36]
[01:39:36] Writing local files
[01:39:36] Using table 3
[01:39:36] Completed 319854 out of 20000000 steps (2)
[01:39:36] Extra SSE boost OK.
If I click on my old F@H and the new one, they have the same protein. The new F@H will show an error in a minute.


83 posted on 11/30/2006 5:51:02 PM PST by processing please hold
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To: processing please hold

TB, I would reccommend she does a search, and dumps all instances of FAH, and starts over. Sounds like the old one is still there.


84 posted on 11/30/2006 6:10:02 PM PST by dfwddr (Join our Folding@Home team (Team# 36120) keyword:folding.)
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To: processing please hold

dfwddr is right. F@H is pulling the existing WU and client.cfg, not allowing you to reinstall the program.

Check your FReepmail.

Life will soon be good.


85 posted on 11/30/2006 6:24:40 PM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: dfwddr

Hey, we made it up to #58.

Great things happened While You Were Sleeping.


86 posted on 11/30/2006 6:25:46 PM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster

Thanks, both of you. Better I lost it now than when I was almost finished with another wu. I'll check my mail.


87 posted on 11/30/2006 6:26:56 PM PST by processing please hold
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To: texas booster

I was just researching the DU team, and they're scheduled to overtake "TITS ----> ( . Y . ) <---- TITS" (remember them?) in 20 days.


What do you bet they choke ?????


88 posted on 11/30/2006 6:33:41 PM PST by dfwddr (Join our Folding@Home team (Team# 36120) keyword:folding.)
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To: dfwddr

Well, the guys will brush right past them trailing a fucia boa.

Now the DU womyn may stop folding while they pass just to stare.

In case they ask, yes those "TITS ----> ( . Y . ) <---- TITS" are real.

DU has leveled off at 10,000 PPD and may soon drop below that for good. They will have a very hard time making it to 140.

Has DU even had a folding thread lately?


89 posted on 11/30/2006 6:53:55 PM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster
Has DU even had a folding thread lately?

I've randomly searched for one over the last couple of months, and haven't found one. Some other quick DU stats, to bookmark the date, they have 63 ppl with a PPD avg (#63 = 1 PPD), and 57 with points this week. They theoretically could get to the #59 position, but it would take them a bit over 15 years, not counting overtakes. With overtakes, and a declining PPD, they'll be lucky to reach 100.

90 posted on 11/30/2006 7:07:47 PM PST by dfwddr (Join our Folding@Home team (Team# 36120) keyword:folding.)
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To: texas booster
I think I have it. I can't tell if both processors are working though.

Verifying core Core_79.fah...
Signature is VALID

Trying to unzip core FahCore_79.exe
Decompressed FahCore_79.exe (2334720 bytes) successfully
+ Core successfully engaged

+ Processing work unit
Core required: FahCore_79.exe
Core found.
Working on Unit 01 [December 1 04:48:29]

+ Working ... *------------------------------*
Folding@Home Double Gromacs Core
Version 1.91 (April 11, 2006)

Preparing to commence simulation
- Looking at optimizations...
- Created dyn
- Files status OK
- Expanded 840309 -> 3234369 (decompressed 384.9 percent)
- Starting from initial work packet

Project: 997 (Run 4679, Clone 0, Gen 32)

Assembly optimizations on if available.
Entering M.D.
Protein: p997_sundfkcomp

Writing local files
Extra SSE2 boost OK.
Writing local files
Completed 0 out of 100000 steps (0)

91 posted on 11/30/2006 9:03:47 PM PST by processing please hold
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To: processing please hold

That looks very good. And you will like the Double Groamcs core for points.

The easiest way tell if both WUs are working is the old CTRL-ALT-DEL. If you see two cores running then all is well.


92 posted on 11/30/2006 9:11:36 PM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster
The easiest way tell if both WUs are working is the old CTRL-ALT-DEL. If you see two cores running then all is well.

I'll remember that. Thank you for all your help. Now I can go to bed and let it do it's thing. :-)

93 posted on 11/30/2006 9:18:08 PM PST by processing please hold
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To: processing please hold
Goof morning.

What on earth did I do wrong, and is it fixable?

############################################################################### Launch directory: C:\Program Files\F@H (2)
Executable: C:\Program Files\F@H (2)\FAH504-Console.exe

[05:25:50] - Ask before connecting: No
[05:25:50] - User name: pbrown (Team 36120)
[05:25:50] - User ID: 499E21481F205083
[05:25:50] - Machine ID: 2
[11:26:09] Completed 65000 out of 500000 steps (13)
[11:26:59] Writing checkpoint files
[11:30:02] Writing checkpoint files
[11:33:06] Writing checkpoint files
[11:36:10] Writing checkpoint files
[11:39:14] Writing checkpoint files
[11:42:15] Writing checkpoint files
[11:45:16] Writing checkpoint files
[11:48:24] Writing checkpoint files
[11:51:23] Writing checkpoint files
[11:53:42] Writing local files
[11:53:42] Completed 70000 out of 500000 steps (14)
[11:54:23] Writing checkpoint files
[11:57:26] Writing checkpoint files
[12:00:28] Writing checkpoint files
[12:03:30] Writing checkpoint files
[12:06:32] Writing checkpoint files
[12:09:32] Writing checkpoint files
[12:12:32] Writing checkpoint files
[12:15:32] Writing checkpoint files
[12:18:33] Writing checkpoint files
[12:21:12] Writing local files
[12:21:12] Completed 75000 out of 500000 steps (15)
[12:21:36] Writing checkpoint files
[12:24:38] Writing checkpoint files
[12:27:39] Writing checkpoint files
[12:30:46] Writing checkpoint files
[12:33:53] Writing checkpoint files
[12:36:54] Writing checkpoint files
[12:39:58] Writing checkpoint files

94 posted on 12/01/2006 4:51:53 AM PST by processing please hold
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To: processing please hold

Actually everything is fine. Its just chugging right along.

I would perhaps set the checkpoint save time to longer than 3 minutes, but that is a minor nit.

Now we know that the second core is happy. How is the first F@H doing?


95 posted on 12/01/2006 5:29:30 AM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster
If I can piddle with it correctly, I'll fix it. I don't know what possessed me to do that. I guess the frequency of our electricity always going out.

Now we know that the second core is happy. How is the first F@H doing?

It showed 63% completed when I checked this morning.

96 posted on 12/01/2006 5:40:36 AM PST by processing please hold
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To: processing please hold

Saving extra checkpoints is no big deal, especially since you have electrical problems.

Maybe a cheap battery back up for Christmas?

I'll post later when I get to work.


97 posted on 12/01/2006 6:00:01 AM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: texas booster
Maybe a cheap battery back up for Christmas?

I have double AA's, will that work? Just kidding. My daughter will know what I need, I'll ask her. I am getting a beautiful new desk though, the furniture store let it slip on their delivery date. Hubby will never know I know. Bless him. :-)

98 posted on 12/01/2006 6:40:18 AM PST by processing please hold
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To: texas booster
[settings]
username=pbrown
team=36120
asknet=no
machineid=2

[http]
active=no
host=localhost
port=8080
usereg=no

[core]
cpuusage=95%
checkpoint=3

Can I just backspace on my checkpoint=3 and get rid of the constant checkpoint breaks?

99 posted on 12/01/2006 8:42:05 AM PST by processing please hold
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To: processing please hold

No, you need to have a setting between 3 and 30. I keep mine set a 30 minutes in most cases.

15 minutes is the default and works OK for most folks.


100 posted on 12/01/2006 9:04:37 AM PST by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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