I've started to lay the groundwork to do just that. I've had about enough of ME. I've reinstalled it 3 times this week and I still get "Explorer.exe has caused a problem with kernel32.dll" at start up..then freezes and several programs I need simply will not run from CD any longer.
I just need to figure out if I want Home or Pro version. Since I will have to put it on two PCs...I'll probably have to get Pro. I believe the license allows 1 or 2 PC installation where Home does not.
Make the move -- just remember that Pro is going to be more of a hassle to maintain. It i really designed for businesses that have LAN admin departments.
Google 'regseeker', download and run it. It found over 1100 invalid registry entries the first time I ran it. It took a little courage to press the delete key, but it never caused any problems and solved many. It has a back-up feature just in case. Also, Firefox did wonders for surfing.