Groundbreaking study identifies two bacteria in the gut that trigger MS

expose-news.com ^ | August 5, 2025 | Rhoda Wilson, Dr. Jessica Rose

[ransomnote]

A groundbreaking study published in PNAS has identified two gut bacteria as triggers for Multiple Sclerosis (“MS”).

The study involved 81 pairs of identical twins, where only one sibling had MS, and found that these bacteria were consistently linked to MS.

The researchers transplanted gut microbes from MS-affected twins into germ-free mice, which developed MS-like symptoms, establishing a causal link between the bacteria and the disease.

A New Multiple Sclerosis Study Is Actually Ground-Breaking

By Dr. Jessica Rose, 29 July 2025

A study was published on 21 April 2025 in PNAS entitled ‘Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice—An unbiased functional study’.¹ Strategic identification of gut bacteria functionally linked to the development of multiple sclerosis (“MS”) is no small feat and this is precisely what the authors have done.

This study is designed really well and has excellent controls and actually causally links two specific gut bacteria called Eisenbergiella tayi and Lachnoclostridium are “likely responsible for an increased incidence of disease.” They are both really important to gut metabolism. Wikipedia calls Lachnoclostridium “obsolete” for some reason.

On Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disease resulting in damage to myelin – the insulating covers of nerve cells – in the brain and spinal cord.²

Over 1 million Americans suffer from MS and it can be quite debilitating depending on the degree and location of demyelination (damage to myelin). It is an autoimmune disease (the body’s immune cells (T and B) attack myelin), characterised by the formation of lesions or “plaques” in the central nervous system (“CNS”), inflammation and destruction of neuronal myelin sheaths.

MORE AT THE LINK: https://expose-news.com/2025/08/05/two-bacteria-in-the-gut-that-trigger-ms/ 

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TOPICS: Miscellaneous
KEYWORDS: bacteria; begonefoultrolls; bionicseamonkeys; garbagesource; garbagetroll; gitract; gutbacteria; ms; randomnut; tcoyh

[TheThirdRuffian]

Sounds like a job for antibiotics and probiotics.

[Red Badger]

Ping!...................

[Red Badger]

Ping!...................

[Carry_Okie]

One would have thought this would have been found a long time ago correlating MS with antibiotic treatments.

There has to be more to this.

[ProtectOurFreedom]

I am always amazed at the role of the gut in our health.

My BIL (about 70) has MS and is doing poorly. He’s had it since his 30s. Our next door neighbor’s daughter (now 39) has MS, but she has benefitted from new advanced treatments that my BIL didn’t have. It’s such a debilitating, horrid disease.

My dad died from Parkinsons which was as bad as MS.

[Fungi]

Maybe a corelation to ALS too?

[so_real]

This is excellent. I hope successes like this spark a whole new wave of research. I have long held belief that a similar causal relationship exists with Parkinson disease. It's my believe that it is bacteria or bacterial waste that dogs can smell when trained to point on Parkinson sufferers. I think we'll be shocked at how much good gut health fixes disease --- we just gotta get Big Pharma and Big Ag to quit destroying gut biomes with what passes for food these days.

[ProtectOurFreedom]

What an amazing experimental method.
1. Find identical twins, one with MS and one without.
2. Isolate the gut bacteria in the twin without MS.
3. Inject that isolated bacteria into germ-free mice. There are 500 to 1,000 distinct bacterial species in the gut at any given time. The number varies based on diet, environment, and individual health.

The total number of bacterial types (including strains) is harder to pin down.

Studies indicate the gut microbiome contains TRILLIONS of individual bacteria, with the most dominant phyla being Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria.

Imagine proposing that a certain gut bacteria causes MS. How would you possibly isolate it? This research boggles me. It makes being a mechanical engineer look like child's play.

[Wuli]

Too many in the “medical profession” know nothing about the importance of a healthy gut biome, and in their practice are unable to make any connections between it and symptoms their patients are having.

A.I. is needed in medicine, if only to quickly do research the medical practitioner has no time for.

[nagant]

This proves that the vagus nerve is a super highway for germs from the intestines to enter the brain.

[Faith65]

Thanks, RN!
BKMK

[T.B. Yoits]

'Why Eating Dirt (aka Soil-Based Organisms) Should Be Part of Your Daily Routine' by Dr. Josh Axe, DC, DNM, CN

https://draxe.com/nutrition/eating-dirt/

[Chainmail]

MS ping

[fso301]

Why does this remind me of the once “Settled Science” of stomach ulcers?

[TheThirdRuffian]

The two bacteria are pretty resistant to most common antibiotics, at least one common for sepsis.

Probably require a combo antibiotic treatment plus a near complete replacement of your gut biome with similar, but not harmful, bacteria.

Very doable, however.

[Ge0ffrey]

Good bowel habits and good dental care are very important.

[Buttons12]

A friend of mine has MS, blames it on a severe case of chicken pox. (So does the doctor.)

[Revel]

Not a problem if you drink plenty of bleach....LOL

[ConservativeMind]

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Thanks ransomnote!