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Drug may prevent COVID-19 in exposed people within households, major trial finds
https://medicalxpress.com/ ^ | 3/12/2025 | by University of Virginia

Posted on 03/30/2025 10:29:42 AM PDT by bitt

An international clinical trial has identified a medication that can help prevent symptomatic COVID-19 in people exposed within households. The results could be particularly important for families where someone is at high risk of serious complications from the illness.

The drug, ensitrelvir, is already approved in Japan to treat mild to moderate COVID cases. The SCORPIO-PEP trial, however, has demonstrated that it also has the potential to protect against illness. Uninfected people who began taking the antiviral within 72 hours of symptoms first appearing in a household member were significantly less likely to contract COVID-19 than people who were given an inactive placebo.

Among the more than 2,000 trial participants in the United States and abroad, 9% of the participants taking the placebo developed confirmed cases of COVID-19. That's compared with only 2.9% of people taking ensitrelvir—a 67% reduction in risk of COVID-19 illness.

"In addition to vaccination, post-exposure prophylaxis with timely use of an oral antiviral would be a valuable way to help prevent COVID-19 illness in people who have been exposed, especially people at high risk for severe disease," said University of Virginia School of Medicine emeritus professor Frederick G. Hayden, MD, who helped design the trial and presented the trial results today at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

Conducted between June 2023 and September 2024, the SCORPIO-PEP trial was double-blinded, meaning neither the researchers nor the uninfected household participants knew whether they were receiving ensitrelvir or placebo. Household members who took a 5-day course of ensitrelvir after exposure to a proven COVID illness were much less likely to get COVID but no more likely to suffer adverse events than those who took placebo.

(Excerpt) Read more at medicalxpress.com ...


TOPICS:
KEYWORDS: chinavirus; chinavirustreatment; covid19; ensitrelvir
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1 posted on 03/30/2025 10:29:42 AM PDT by bitt
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To: null and void; aragorn; EnigmaticAnomaly; kalee; Kale; AZ .44 MAG; Baynative; bgill; bitt; ...

p


2 posted on 03/30/2025 10:29:56 AM PDT by bitt (<img src=' 'width=30%>)
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To: bitt

3 posted on 03/30/2025 10:33:27 AM PDT by Pollard (Zone 6b)
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To: bitt

No Thanks! Did not fall for this jive the first time, not going to start now..


4 posted on 03/30/2025 10:38:11 AM PDT by sonova (No money? You're free to go.)
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To: bitt

Drug here, drug there...shot here, shot there...havent they got it in water systems yet?


5 posted on 03/30/2025 10:41:22 AM PDT by goodnesswins (Democracy to Democrats is stealing other peoples money for their use, no matter how idiotic)
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To: bitt
It's very difficult to find sanity when the snake-oil hucksters bribe congress with billions. It's best at this point to be a contrarean and trust your own judgment after enough of life's experiences. I remember when Covid shots started there were people that walked around displaying their Vax Cards to others, like it was a club or something?

If it's being sold, I don't want it. Period.

6 posted on 03/30/2025 10:45:09 AM PDT by blackdog ((Z28.310) Be careful what you say. Your refrigerator may be listening & reporting you.)
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To: bitt

Why worry about it. Five years after the world’s greatest psych op, more and more people are starting to understand it was a scam. Nobody except the paranoid even think about it any more.


7 posted on 03/30/2025 10:54:21 AM PDT by GrumpyOldGuy
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To: bitt

Maybe.


8 posted on 03/30/2025 10:55:37 AM PDT by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
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To: bitt

They will not recommend ivermectin. No matter what.


9 posted on 03/30/2025 10:55:55 AM PDT by Soul of the South (The past is gone and cannot be changed. Tomorrow can be a better day if we work on it.)
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To: bitt

Just in time for five years too late.


10 posted on 03/30/2025 10:58:34 AM PDT by webheart (Why not write out because instead of saying b/c and with instead of w/ ?)
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To: webheart

11 posted on 03/30/2025 10:59:43 AM PDT by ClearCase_guy
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To: bitt

I thought that’s what the vaccine was supposed to do? /s


12 posted on 03/30/2025 11:11:22 AM PDT by miliantnutcase
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To: bitt

Took another big dose of “nope” just now.


13 posted on 03/30/2025 11:21:00 AM PDT by Worldtraveler once upon a time (Degrow government)
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To: bitt

But but but,,, I thought that was/is what the vax was for???????
No thanks to either!


14 posted on 03/30/2025 11:21:48 AM PDT by Recompennation
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To: bitt

Why are they still pushing this? They never do this for colds, stomach viruses, or cold sores.


15 posted on 03/30/2025 11:27:25 AM PDT by madison10 (God chose Prrsident Trump. Satan chose judges and Democrats.)
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To: bitt

2 original shots and 4 or 5 boosters my sister took. She just called me earlier today to say she has covid. It was hard not to laugh.


16 posted on 03/30/2025 11:28:40 AM PDT by dynachrome (Auslander Raus!)
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To: bitt

The psyop continues...


17 posted on 03/30/2025 11:29:30 AM PDT by 9YearLurker
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To: bitt

So - what are covid rates and survival rates these days?

Wife an I both over 70 - neither took the jabs - she got covid 2 years ago and I had symptoms about 4 days after hers started...doctor down her (MS Gulf Coast) said the drug that Big Pharm wanted to treat it with had too many “issues” so she opted to treat the symptoms - cold meds, antibiotics and steroid inhaler for wife. I just used cold meds with Mucinex D - we were both never really ill and were feeling decent within 4 days of initial onsets - totally normal by day 7.


18 posted on 03/30/2025 11:34:06 AM PDT by trebb (So many fools - so little time...)
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To: bitt

They lost me at “covid-19 drug” .


19 posted on 03/30/2025 11:57:49 AM PDT by circlecity
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To: Pollard

Exactly. And toss a bit of magnesium in there, too.


20 posted on 03/30/2025 12:04:42 PM PDT by curious7
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