Posted on 02/01/2025 9:35:47 PM PST by ConservativeMind
Collagen is the most abundant protein in our body. All our musculoskeletal tissues are built on a foundation of collagen. Collagen makes up our tendons, ligaments and bones. For this musculoskeletal system to work well, we need to have a good collagen turnover that replaces older collagen with new ones.
Collagen is a meat-based protein. Animal tissues are the only natural source of collagen.
Our studies have shown that when taking a collagen supplement, there is an increase in a circulating marker (known as procollagen N-Terminal peptide) of collagen synthesis. So, we know that hydrolyzed collagen supplements can be good. This is especially true in older individuals.
More collagen largely means more protein with specific amino acids needed to make collagen in our bodies. In many cases, there seems to be a nice upside.
To build collagen, we need a lot of glycine and proline amino acids. If there isn't enough glycine or proline, then we can't make as much collagen as we want.
But, since whey has all the amino acids and is a complete protein, unlike collagen, it is a high quality protein. Whey has a lot of leucine, a key amino acid for protein synthesis, and proline. However, it is not as rich in glycine, a building block of collagen.
We found that when people are fed milk protein like whey, their glycine levels in blood would go down. They wondered if that happened because the body was using the glycine to make more collagen.
Our study showed that we can make more connective tissue in our muscles by taking a whey protein and collagen blend.
This study was the first time we have demonstrated, using a direct measure of collagen synthesis, that we can nutritionally change how much collagen we make in our muscles.
(Excerpt) Read more at medicalxpress.com ...
Omega-3 fats only helped if the tissue had inflammation, already.
Do note that adding whey to collagen, while you are expecting to have the collagen do something else, may not be as helpful.
So if you take Type II collagen for joints and add whey to it, it might not do as good of a job for your joints, as now you have a complete protein that can be used elsewhere.
No whey.
Hey, I’m just kidding. I haven’t a clue what collagen, omega-3 and whey supplements do to bones.
bookmark to read tomorrow.
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Interesting stuff. I take all of it but I have no sense how the pieces work together and what the correct ratio should be.
I saw your ratios. But I did not understand them. I’ll do some research on them. I’m reading that the chinese ai deepseek.com has some good medical capabilities.
I would think that omega 3 bone health benefits and anti inflamnatory benefits would be secondary to its other benefits.
In the last year, I cleared out blockage in my left carotid arterie that had been there for a decade by dropping 30 pounds and and taking a bunch of supplements and prescription drugs. So many that I’m not sure which one did the job.
But I read recently that high dose omega 3 will clear out the arteries. I was taking close to 5 grams of omega 3 for about six months before cutting that number in half.
I dropped my ldl cholesteral to dangerously low for a a couple months with a couple different cholesterol lowering drugs.
I did that for about 2 months before stopping. I think that gave me a case of gall stones. That resolved when I went off the pharmaceuticals.
I have been taking a gradually increasing batch of supplements for more than 50 years. I was taking calcium and magnesium for muscle cramps and height shrinkage. Around age 55 I read that boron helps utilization of cal/mag and bond building. I added 3 mg. a day and back pain and the occasional cramps went away. Around age 75 I started having back pain again and occasional knee tenderness. I added another 3 mg. boron with my night supplements. I am now 86 and the back and knee issues have been gpme all this time.
Good that you lost 30 lbs, but bad that you got gall stones. If you seriously reduced your fat consumption to lose that weight, that could have influenced the gall stones. Fat in the diet causes the gall bladder to dump gall and thus prevent stone formation. I wonder if the amount of Omega 3 fatty acid was sufficient to help the gall bladder dump its load, especially when you reduced the dose by half? Glad everything seems to be working well now for you.
Or, how about consuming some meat, fish and milk?
Right now great diagnostics are available. Those diagnostics/tests are what will enable people to fine tune their medications/diet/exercise etc. As well, the ability to plug your bloodwork and such into an AI is already available. That helps. But it’s all first-generation stuff.
In a couple years the test numbers coupled with the AI at a reasonable price point will make for pretty radical shift in the medicine is done. Everything will be individually targeted rather than the one size fits all strategy.
My understanding: Many claimed benefits lack substantial scientific support, and more research is needed to confirm the effectiveness of collagen supplements
In other words, if you are a horse take collagen where it is believed to be effective. Humans, maybe not.
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