Genomic differences between developing male and female brains in the womb

New research by scientists at the University of Exeter and King's College London has made significant progress towards understanding the complex process of prenatal human brain development..The study focussed on the molecular "switches" that regulate the way that genes are activated without changing the underlying DNA blueprint. These processes, known as epigenetics, direct the way in which different cells and tissue types develop, and help differentiate brain cells from those in other parts of the body.

Significant changes in DNA methylation across brain development were found at more than 7% of the 400,000 genomic sites assessed. ...

The term ‘epigenetics’ was introduced in 1942 by embryologist Conrad Waddington. The original definition saw epigenetics as ‘the complex of developmental processes between the genotype and phenotype’. This research field has experienced a radical revolution in the last 50 years, leading to changes in the way we understand the developmental process. The new working definition sees epigenetics as the study of ‘heritable changes in gene function that cannot be explained by changes in DNA sequence’ ...

How can humans share 99.9% of their DNA with one other, yet hold so much diversity? Epigenetics may hold the answer....

Identical twins are born with the same DNA and have near-identical epigenetic tags at birth. Epigenetic changes which cause two identical strands of DNA to become completely unique are thought to start in the womb and are the only detectable differences at birth. - https://oxsci.org/epigenetics-explained/

Epigenetic regulation is retained from the parental sperm and egg and undergoes multiple rounds of reprogramming to assume a baseline epigenetic profile in the developing fetus. Some epigenetic marks persist through these reprogramming stages, allowing epigenetic transmission from earlier generation(s). Some epigenetic marks are acquired de novo due to the environment during pregnancy and during organ development in utero. After birth, epigenetic patterns continue to change most rapidly during growth and development in childhood and adolescence. Epigenetic modifications are continually acquired throughout life. The resultant epigenetic state in adulthood is then passed on to the next generation through the germ cells, and the cycle repeats. - https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-024-01762-3

Adding more weight to the maxim, "It all depends on how you were raised," though being born of the Spirit can effect profound basic changes in heart and life.

“ Using cutting-edge technology, the researchers measured genome-wide patterns of DNA methylation in nearly 200 samples, spanning 23 to 184 days after conception.”

Sick.

Where are they getting human fetal brain samples?

Read my tagline.

Aside from that the way it’s described is pedestrian me too science.

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