Posted on 11/04/2024 7:57:58 PM PST by ConservativeMind
Topically applied products containing human platelet extract or vitamin C provide similar improvements in age spots (photoaging) of the hands, as reported in a clinical trial.
Brown spots on the hands, sometimes referred to as age spots or liver spots, are a common cosmetic issue caused by sun damage to the skin. Treatments for skin rejuvenation and resurfacing—such as chemical peels, injectables, and intense pulsed light or laser treatments—have primarily focused on the face.
The study included 60 patients, average age 52.5 years, with moderate photoaging on the back (dorsum) of the hand. Each patient followed a standardized skincare routine, including twice-daily topical applications of human platelet extract containing–platelet exosomes (HPE) to the right hand and vitamin C to the left hand. Digital imaging and other assessments were used to assess measures of photoaging after 12 to 26 weeks of use.
HPE and vitamin C 'are both effective treatments for skin rejuvenation' Based on a wide range of photoaging parameters, topical HPE was "non-inferior" to vitamin C. After 12 weeks, the two products produced similar reductions in the skin area affected by brown spots and wrinkles and improved skin luminosity and color evenness.
By 26 weeks, the brown spot fractional area had decreased by approximately 23% with topical HPE and 26% with vitamin C. The outcome measures were not statistically different between the two topicals.
Outcomes with both topicals were similar to those reported in previous clinical trials of intense pulsed light therapy—an established nonsurgical treatment for photoaging.
Dr. Wyles comments, "While both human platelet extract, or platelet exosomes, and vitamin C may have similar rejuvenating effects, topical vitamin C can increase photosensitivity, disrupt skin's pH balance, and have stability issues, making HPE a more reliable and skin-friendly alternative."
(Excerpt) Read more at medicalxpress.com ...
HPE is available and one form goes by the name “Renewosome.”
I’d consider the vitamin C and sunscreen while using it.
Bkmk
Topical Vitamin C?
A cream or ointment? Or just vitamin C powder mixed with water?
And how long was it on?
They said
vitamin C (C E Ferulic with 15% L-ascorbic acid - skinCeuticals)
Described the details of use in the ‘Patients and Methods’ section of the paper.
What about the light spots in tanned areas?
My mom had a jar of Esoterica for that, but I don’t know if it worked.
It’s funny you should mention esoterica. I once had the opportunity to take Senegal embassy workers to Bloomingdale’s and they came out with three tennis bags filled with esoterica. Who were they for their girlfriends? So it does work on black skin and should work on dark dark spots on your hands..
Natural African Shea Butter is very nourishing to the skin and over time can fade dark spots which it did for mine. There are also cosmetics with Shea Butter for hair and skin. More information at Google
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