Interesting. Worth trying drugs that are already out there for other illnesses...they might need tweaking...but worth a try.
As for genetics, with my disastrous lifestyle regarding health at least, doctors are shocked when they can’t find swollen ankles, heart issues, kidney issues, bad fats levels.
I KNOW that at 56, my luck will run out sooner than later and I am working on it.
But guys I know around my age that lead the same kind of lifestyle are Disasters...heart attacks, edema, kidney disease.
Genes make a tremendous difference for each individual.
OR the 23 years of healthy living and playing lots of sports carried over for some decades...but not for much longer.
Have a good one
I’ve had about 6 or so gout flares over the last 10 years. A couple weren’t too bad. A couple were middling and then a couple were practically crippling and extremely painful for 5-6 days. I’ve tried cutting way back on various things....shellfish, red meat, especially processed meats like bacon, sausages, etc. What I really cut back on after the last time is all alcohol but most especially beer. I’ve had about 4-5 drinks in the last 8 months. So far so good, but I hate it because I really do enjoy an occasional beer or two.
I could not believe how painful Gout is, really bad.
I thought I remember reading other papers decades ago about “close families” and gout. Not just a rich lifestyle...
Interesting.
If genetic, then why does it come later in life, like all other degenerative diseases?
If genetic, then why does it go away when filtration issues (kidney health) are resolved?
The products sold by Standard Process (Rena Food and Renatrophin) virtually eliminate gout, as does juicing. That doesn’t sound like a genetic issue.
Tart cherry juice and magnesium supplement lessen the severity and length of my flare ups. Bookmarking.
” “People need to understand that while specific dietary factors, such as eating red meat, can trigger gout attacks”
HALF right. Specific dietary factors, FOR YOU!
Both what specific dietary factors brings on an attack or helps soothe an attack is DIFFERENT for each individual.
Blaming “red meat” is a red herring! (pi)
I have had SEVERE gout attacks, many. Unable to walk without crutches, unable to lay down or sleep.
What does work is Indomethacin. Some relief in a few hours, total relief in a few days. It was a MIRACLE drug for me.
Then, take Allopurinol every day. Gout will mostly be in your past, without giving up red meat or drinking cherry juice.
Colchicine never worked for me, besides “Colchicine can cause serious side effects or death if levels of colchicine are too high in your body.”
I get an attack maybe once a year, I keep Indomethacin handy, just in case.
Maybe genetics plays a part, but neither of my parents had it. I, on the other hand, had a severe case starting the day after eating 8 pieces of Mackerel nigiri. This was over 10 years ago. I cut down on purines in my diet and the problem has never returned.
Among numerous other health improvements, I stopped getting gout flare ups when I adopted a ketogenic diet. Our bodies are not meant to be run on carbs.
Uric acid crystals that form in the joints are the cause of the pain of gout. Uric acid crystals are also (for most sufferers of kidney stones) what form in the kidneys are and are then renamed “kidney stones.”
I used to average at least one kidney stone about every 1.5 months. The size of the stones averaged 4mm-6mm. When traveling from the kidney to the bladder, they felt like they were 3 times that size. The pain was excruciating.
The last one I had was a 6mm jagged stone that put me in the hospital. While I was there, a friend advised me to try “Chanca Piedra.” It is an OTC herbal blend that dissolves uric acid crystals. I am now 1 year down the road from my last kidney stone. Not even a tiny one... It has been a Godsend.
I take one capsule a day. Cost runs about $18/200 capsules on Amazon.
I shared my experience with Chanca Piedra with my gout suffering friends. They tried it and it has worked for them as well. As cheap as it is, it’s worth a shot.