Posted on 12/27/2022 8:24:28 AM PST by SeekAndFind
The COVID-19 antiviral drug Molnupiravir helps speed up recovery from the virus but does not reduce the hospitalization or death rate in higher-risk vaccinated adults, a new study has found.
Molnupiravir, from Ridgeback Biotherapeutics and Merck & Co. is used to treat mild to moderate COVID-19 and can be taken at home, twice a day for five days, within five days of symptoms onset.
It works by stopping the virus from replicating, keeping levels low in the body, thus reducing its severity.
The study was published in The Lancet on Dec. 22 and has been peer reviewed.
Between Dec. 8, 2021 and April 27, 2022, more than 25,700 eligible participants in the UK aged 50 or older—or 18 or older with relevant comorbidities—who had been unwell with confirmed COVID-19 for five days or less took part in the study, which was conducted when the Omicron variant was dominant.
Half of the participants were randomly assigned to receive an 800 milligram dose of Molnupiravir twice daily for five days and the other half were assigned to receive usual hospital care only.
The mean age of participants was 56.6 years and 94 percent had received at least three doses of a SARS-CoV-2 vaccine.
Researchers conducted a follow-up of the participants either via an online diary or a telephone call within 28 days. They found that hospitalizations or deaths were recorded in 105 (1 percent) of the 12,529 participants who received Molnupiravir, versus 98 hospitalizations or deaths (1 percent) recorded in the 12,525 participants who were given usual care.
The study did, however, find that participants who received Molnupiravir recovered faster than those who received usual care, had a higher rate of early sustained recovery, saw a reduced viral load, and sought fewer general practitioner consultations. Twenty percent of the Molnupiravir patients sought GP consultations compared to 24 percent of those who received usual care, a slight difference.
Participants who received Molnupiravir reported a median recovery time of nine days compared with 15 days for those only receiving usual care, the study found, with researchers stating that further analysis suggested that Molnupiravir sped up recovery by 4.2 days on average.
“This analysis of the largest randomized trial involving people vaccinated against SARS-CoV-2 infection who are at increased risk of adverse outcomes in the community and unwell with COVID-19 showed that the early addition of Molnupiravir to usual care did not reduce hospital admissions or death (which were low in both treatment groups),” the study authors noted.
“However, participants in the Molnupiravir plus usual care group recovered faster than those in the usual care group, had a higher rate of early sustained recovery, and had fewer general practitioner consultations,” they added.
In November 2021, Merck said results of its MOVe-OUT study of Molnupiravir showed that the oral antiviral medicine was 30 percent effective in reducing hospitalizations. However, that study was conducted among unvaccinated adults.
Shortly after, the UK became the first country to approve Molnupiravir for the treatment of mild to moderate COVID-19 in those with other risk factors, such as obesity, diabetes, or those over 60 years old.
The National Institute for Health and Care Excellence (NICE), which provides national guidance and advice to improve health and social care in the UK, has recommended individuals stop using five COVID-19 treatments, including Merck’s antiviral pill, to treat the virus, stating that “while there is some clinical evidence that they are effective at treating COVID-19 they were not found to be cost-effective.”
Chris Butler, professor of primary care in the Nuffield Department of Primary Care Health Sciences at Oxford University and co-chief investigator, said at a Science Media Centre briefing following the publication of the study that the results indicate that Molnupiravir could help ease the burden of UK health services which are under pressure and could also be used to help get key workers back to work quicker, as it aids with speeding up recovery from COVID-19.
However, Richard Hobbs, Nuffield professor of primary care at Oxford and co-investigator, noted the high price associated with the antiviral drug, which is estimated to cost several hundred pounds for a five-day course.
“Molnupiravir is a high-cost antiviral. Its deployment will depend on how much a mean four days’ improvement in symptoms will benefit the country,” Hobbs told the briefing.
Molnupiravir made nearly $5 billion in sales for Merck in the first three quarters of 2022.
Then it did exactly what it was supposed to do after all...
Behold my shocked face…
This planets biggest scam operation is Big Pharma.
What happened to Tamiflu?
All it did was give the person more things to worry about
We are seeing the greatest transfer of wealth in history to the global corporate class. That’s what these worthless drugs and the vax is all part of. The globalists know the crash is coming. They are implementing it.
Molnupiravir, from Merck & Co. is taken at home, twice a day for five days or until profits improve.
Hooda thunkit?
High risk people are going to continue dying from Covid... That’s the best thing about this disease... It kills the weak, not the strong. Those with good immune systems survive... If this truly were a virus that killed healthy people, there would have been hundreds of millions dead... Not 6 or 7 million. And isolating health people along with the sick would have exacerbated the situation.
If we ever do get hit with a disease that is deadly to healthy people, we will need to isolate the sick people from the healthy and not group everybody together.
https://en.wikipedia.org/wiki/Lancet_letter_(COVID-19)
Tamiflu never really worked either, MAYBE shortening illness by one day ... MAYBE... and only if taken 24 hours after symptoms, so good luck with that ... AND it has a HORRIFIC side-effect profile ... i know people who took and said it was the worst drug they had every taken ... and that it didn’t help their influenza one iota ...
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