[ConservativeMind]

At the very least, even if the drugs aren’t responsible for the added risk, get your diabetes under control and also try to reduce, in a healthy way, the root causes of your pain.

[ConservativeMind]

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[BipolarBob]

And they can cause your cataracts to worsen significantly. Nsaids should be used cautiously and as infrequently as possible.

[catnipman]

and there’s the well documented role of NSAIDs in kidney damage caused by the triple whammy ...

https://www.google.com/search?q=nsaids+triple+whammy+kidney

https://www.sciencedirect.com/science/article/abs/pii/S0025556422000232

[Celtic Conservative]

Due to my back I use NSAIDs, but my sugars are rock solid. (5.4 A1C)

CC

[TChad]

NSAID bump for later

[Myrddin]

My bedtime dose of ibuprofen is 800 mg. Every day. It keeps my rheumatoid arthritis in check. When I last went for a colonoscopy in 2013, I was required to discontinue ibuprofen for 2 weeks prior to the procedure. It was almost impossible to sleep with the unsuppressed pain. I did the procedure. They clipped a few polyps. A week later, I needed to mow the lawn. The mower was unwilling to start after a vigorous attempt to start the engine. The bad news follows: a toilet bowl that looked like a tequila sunrise. Off to the hospital. I ripped a scab off one of the polyp "snips" that was right over a blood vessel. It took 6 hours of drinking "Golytely" to clear my gut sufficiently for an emergency colonoscopy to stop the hemorrhaging. My BP was dropping all night. The ER did a type/cross match in case I needed a transfusion. 5:30 AM and off to the OR to stop the bleeder. Another 3 weeks with no ibuprofen (reconnecting to the point of the post). The RA left lots of damage behind without the ibuprofen suppression. I'm not doing that again. An elective procedure. That wasn't all. The "prep" for the original colonoscopy included Amitiza. Minutes after I took that pill, my lungs began filling with fluid. Oh joy! It's only supposed to dump saline fluid in the bowel unless you are one of the unfortunate 0.1% of people who have saline dumped in the lungs. I had to sit up for 6 hours coughing the saline from my lungs to avoid drowning in my own fluids. Never again.

Post script: the DNA submission I did to Ancestry gave me entree to a database that bashed my genetic profile against diseases and medications. My phenotype tolerates ibuprofen with no ill effect. The daily 800 mg dose isn't going to harm me and does keep the RA at bay. My BMI is 20.4. Body fat percentage 15. Weight 154. Satisfactory at almost age 66.

[ckilmer]

NSID’s are killers.

If you do them at all—follow the rules on the box. take them only briefly.

take them for long periods for chronic pain and your cardiovascular system will go hell.