Posted on 07/04/2022 1:16:47 PM PDT by ConservativeMind
Researchers have found a significant difference in the gut microbiota of men with prostate cancer, compared with those who have benign biopsies. Although the finding is an association, it could partly explain the relationship between lifestyle effects and geographical differences in prostate cancer.
Gut microbiota are the collection of microbes in the gastrointestinal tract and they affect processes and mechanisms in the body. The state of gut microbiota has been linked to many conditions, even in organs that are far from the intestines, but their role in prostate cancer is not understood.
Professor Peter Bostrom used samples collected from patients on a prospective multi-center clinical study. They sequenced the gut microbiota of 181 men who were suspected to have prostate cancer and undergoing prostate cancer diagnostics. The microbiota samples were collected at the time of their prostate biopsies after MRI scans.
Sixty percent of the men were diagnosed with prostate cancer, and their gut microbiota profiles were significantly different to those who had benign biopsies. The men with cancer had increased levels of Prevotella 9, members of the family Erysipelotrichaceae, and Escherichia-Shigella, a pathogen that causes diarrhea. They also had lower levels of Jonquetella, Moryella, Anaeroglobus, Corynebacterium and CAG-352 than men without.
Professor Bostrom says that "there are significant variations in prostate cancer rates around the world, which could be due to genetic factors or differences in healthcare policies, but also variance in lifestyle and diet. The difference in gut microbiota between men with and without prostate cancer could underpin some of these variations."
Prostate cancer is the most common male cancer globally. There is evidence that men who emigrate from low to high incidence areas have increased risk of prostate cancer in their lifetimes, and their offspring have the risk of the high incidence region.
(Excerpt) Read more at medicalxpress.com ...
They stress it was just an “association,” but it seems they are strongly, and intimately, tied together.
Gut bacteria can be influenced by what we eat, including cultures from fermented foods and probiotics, along with fibers and other prebiotic substances feeding what is already there. These might help change a dysfunctional gut bacterial status.
It has also been found out that the body can influence what gut bacteria flourish, strangely.
This is a pretty amazing situation to cone across concerning prostate cancer, alone.
men who emigrate from low to high incidence areas have increased risk of prostate cancer in their lifetimes,
One universal common thing among men with prostate problems is the lack of zinc compared to men without problems. The less zinc in the prostate tissues, the worse the problems are.
No surprise gut bacteria is different, zinc helps kill off certain bad bacterias, helps the immune system.
Are you sure “gut” isn’t a typo?
If it’s a strong enough correlation, it could be a diagnostic tool.
So, how does one go about adding more Jonquetella, Moryella, Anaeroglobus, Corynebacterium and CAG-352 to their gut?
From Secret Agent Man, zinc is good. I personally am taking Zinc Picolinate along with Quercetin. Now my question is, What about Dannon Yogurt or cultured butter milk? Culture being beneficial. Should I also go to the symphony orchestras for a more cultured lifestyle. Silliness of intended. Dannon Yogurt? Buttermilk?
Kefir.
I get it the dairy section of the grocery store.
Yep, kefir. Good for so many things.
My dad had prostrate cancer - but that's not what ended his life.
“One universal common thing among men with prostate problems is the lack of zinc compared to men without problems. The less zinc in the prostate tissues, the worse the problems are.
No surprise gut bacteria is different, zinc helps kill off certain bad bacterias, helps the immune system.”
The results of our case-control study suggest that there is a non-linear increase in risk of prostate cancer with increasing intake of zinc which is not statistically significant.
One big factor in common with most men diagnosed with prostate cancer is a very low level of Vitamin D3. It’s one reason that the further you go north, the more likely one is to get prostate cancer. Mine was 27, the very low end of the normal range, when I was diagnosed. I now make sure I take enough Vitamin D3 to keep my level close to the top end of 100.
I was diagnosed with metastatic prostate cancer with mets to 8 places in my bones almost 8 years ago. Currently have an undetectable PSA; and am doing exceedingly well. I also started taking some other supplements that I believe help keep my cancer under control.
If yuor gut can handle the dairy, yogurt is good.
Some brands and types are much better than others though.
ah, but is it the chicken, or the egg?
Congratulations! Did you receive hormone ablation therapy?
The brain and gut are connected…
Hard to know where this starts…
I know four men whose PSA was perfect and whose prostate cancer went undetected because their doctors relied entirely on the PSA and did not physically examine them. Each of them, upon getting a new doctor who did the physical exam, turned out to have sufficiently advanced cancer to require a prostatectomy. One of those still experienced metastates and died. He was my brother. I’m on a mission to make sure as many men as possible don’t let their doctors rely strictly on the PSA to determine prostate health.
As part of Obamacare, some group of doctors determined that men should no longer get DREs and PSAs check because those procedures “cause stress and undue worry.”
Of course that was total bullshit. A radiation oncologist at MD Anderson told me they were expecting a significant increase in advanced prostate cancer patients in the future because of those recommendations.
I am still getting Lupron injections every three months and am taking Xtandi every day.
There is no cure, but my oncologist tells me my cancer may not progress for many years, if ever. That is how well I have responded to treatment. On average, Xtandi works for only 6 months. Some for only a month or two; some for up to 18 months. For me, it will be four years in December. I’ve been blessed.
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