Posted on 06/12/2022 8:03:36 PM PDT by ConservativeMind
Polyphenols in foods we eat can prevent inflammation in older people, since they alter the intestinal microbiota and induce the production of the indole 3-propionic acid (IPA).
Polyphenols are natural compounds, considered probiotics, which we eat mainly through fruits and vegetables.
The study shows the interaction between polyphenols and gut microbiota can induce the proliferation of bacteria with the ability to synthetize beneficial metabolites, such as IPA, a postbiotic with antioxidant, anti-inflammatory and neuroprotective properties that contributes to improve the health of the intestinal wall. Therefore, this compound would contribute to the prevention of some diseases associated with aging.
Researchers carried out a multiomic analysis to monitor the IPA levels in the serum of fifty-one volunteers who kept following a diet rich in polyphenols (green tea, bitter chocolate, fruits including apples, pomegranate and blueberries) for eight weeks.
The results show that the diet rich in polyphenols generated a significant increase in the blood IPA levels, together with a decrease in inflammation levels and changes in the bacteria of the microbiota.
Surprisingly, the researchers did not observe the same effects in the volunteers with kidney diseases. These people showed lower amounts of IPA at the beginning of the trial compared to the volunteers with normal kidney function.
"These results could be clinically relevant, since the low IPA levels have been associated with a rapid decline of kidney function and a chronic kidney disease," notes Professor Andrés-Lacueva.
Therefore, a polyphenol-rich diet including probiotic foods such as green tea, dark chocolate and some fruits like apples, pomegranate and blueberries could increase the production of IPA through changes in the composition of gut microbiota. This increase in the levels of a postbiotic, such as IPA in the elderly, could be beneficial in delaying or preventing chronic diseases that harm the quality of life.
(Excerpt) Read more at medicalxpress.com ...
1000mg pill every other day.
Thank you!
Chocolate and blue berries - nice choices...
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