Posted on 04/25/2022 10:50:48 AM PDT by ConservativeMind
A calorie-reduced diet can not only delay the development of metabolic diseases, but also has a positive effect on the immune system. Researchers have now shown for the first time that this effect is mediated by an altered gut microbiome, which slows down the deterioration of the immune system in old age (immune senescence).
Around 2 billion people worldwide are overweight. Obesity increases the risk of developing high blood pressure, heart attack or type 2 diabetes mellitus and can cause inflammation in the body that weakens the immune system through an accumulation of specific memory T and B cells. This process is called immune senescence, an age-related change in the immune system. In obese people, the development of metabolic diseases such as type 2 diabetes can be delayed by a low-calorie diet. In addition, such a diet also has a positive effect on the immune system. But exactly how the positive effects are mediated and what role the gut microbiome plays in this process is not known. Researchers have now investigated the interactions between calorie-reduced diets, the microbiome, metabolism and the immune system.
For this purpose, they first analyzed how a very low-calorie diet (800 kcal/day for 8 weeks) affected the gut microbiome of an obese woman. In the next step, the researchers transplanted the gut microbiota before and after the diet intervention into germ-free mice to establish a gnotobiotic mouse model.
By transplanting the diet-altered microbiota, glucose metabolism improved and fat deposition decreased. In addition, mass cytometry showed that the level of specific memory T and B cells was also reduced. "This indicates delayed immune senescence," said Julia Sbierski-Kind, first author of the study.
"These findings suggest that the positive effects of a low-calorie diet on metabolism and the immune system are mediated via the gut microbiome," Sbierski-Kind said.
(Excerpt) Read more at medicalxpress.com ...
How do you know a short life with a full belly provides more comfort than a long life with a sometimes empty belly?
You won’t live longer on an 800 calorie/day diet.
It will just seem longer.
Sauerkraut——great for the gut flora.
Wehn you think about it, how many overweight 80 yr olds have you come across?
Calorie Restriction with or without Time-Restricted Eating in Weight Loss
https://www.nejm.org/doi/full/10.1056/NEJMoa2114833
“My target is 1,800 and that’s hard to achieve.”
If you’re looking for a dietary assistance, here’s one you might use:
Harris Benedict Formula
To determine your total daily calorie needs, multiply your BMR by the appropriate activity factor, as follows:
• If you are sedentary (little or no exercise) : Calorie-Calculation = BMR x 1.2
• If you are lightly active (light exercise/sports 1-3 days/week) : Calorie-Calculation = BMR x 1.375
• If you are moderately active (moderate exercise/sports 3-5 days/week) : Calorie-Calculation = BMR x 1.55
• If you are very active (hard exercise/sports 6-7 days a week) : Calorie-Calculation = BMR x 1.725
• If you are extra active (very hard exercise/sports & physical job or 2x training) : Calorie-Calculation = BMR x 1.9
BMR Formula
Women: BMR = 655 + (4.35 x weight in pounds) + (4.7 x height in inches) - (4.7 x age in years)
Men: BMR = 66 + (6.23 x weight in pounds) + (12.7 x height in inches) - (6.8 x age in years)
Total Calorie Needs Example:
If you are sedentary, multiply your BMR (1745) by 1.2 = 2094. This is the total number of calories you need in order to maintain your current weight.
Once you know the number of calories needed to maintain your weight, you can easily calculate the number of calories you need to eat in order to lose weight subtracting no more than 500 from your answer in daily intake.
This may seem like a lot of work, but this is the equation most of the diets use for controlled weight loss and it will change each time you step on the scale. My suggestion is to set up an excel equation to accomplish it faster and easier. And you will need to recalculate often as your weight will vary almost daily.
Good luck
wy69
800 hundred calories is a snack after lunch.
My routine.
Weekends I am usually “off the wagon” Am doing physical, exertion, social meals...etc. So Monday is my “deep fast”....will have one meal of less that 1K calories. Tue-Fri one meal a day at the local buffet after work. Yes I do control my portions - I dont pig out. And its a healthy cross section of the food spectrum.
Interesting. Must be contributing to my strong immune system. I weigh 116 and often forget to eat. Haven’t always been this way, it just happened gradually as I aged. It’s 11:15 here, and I’m forcing myself to go make breakfast. Two meals a day is all I can shovel in.
My friends hate me. LOL
The Okinawans are some of the longest living and they have as part of cuture is to always leave the table wanting more, a low caloric intake mindset.
They were trying to provoke a dframatic response, in an obese woman no less, and they certainly got it. It is not required to keep a regular diet of that amount. The woman likely consumed 2,500+ per day previously.
I only exercise during my morning fasting period (8 pm to noonish)
Now think how you always heard that breakfast was the most important meal of the day. Now I know the was Big cereal and Big dairy bs hype.
I’m a believer!! I lost kidney function and went on dialysis over 8 years ago due to a rare form of lymphoma. Most lymphomas (blood cancers) have a direct effect on your immune system. It pretty much wipes it out.
I made several lifestyle changes and after three years of dialysis, I was able to come off without a transplant. This was from improved kidney function. I made all of my changes with the full support of my medical team.
One of those changes was a reduced-calorie diet. My daily target is 1000 calories a day and no meat or processed foods. I occasionally go off the wagon and sometimes pig out on sweets, but for the most part, I’ve been doing this for over five years.
So far, so very good!
Man thats gotta suck!
I’m convinced there are some health benefits to fasting occasionally.
But you’ll never convince me there’s any benefit to not eating enough food for months on end.
Your body needs a certain number of calories each day and that’s just it. Limiting yourself to 800 or 1,000 calories a day for months on end is just slowly starving yourself to death.
they’ll be helpful for all of us soon given the pending food shortages.
Wreaks of climate change madness...eat less, make less food.
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