Posted on 02/06/2022 6:24:57 PM PST by bitt
Indiana-based Eli Lilly and Company reported on February 3, 2022, it recently submitted a request for Emergency Use Authorization to the U.S. FDA for bebtelovimab, an investigational anti-SARS-CoV-2 Monoclonal Antibody (mAbs).
Bebtelovimab, which neutralizes the SARS-CoV-2 spike glycoprotein receptor-binding domain-specific antibody, is being evaluated to treat mild-to-moderate COVID-19 in adults and pediatric patients 12 years of age and older.
Lilly's recent financial disclosure says 'authentic virus analysis of bebtelovimab confirmed earlier pseudovirus findings, which demonstrated bebtelovimab neutralizes coronavirus variants of concern, including Omicron.'
The U.S. NIH's OpenData Portal Therapeutic Activity Explorer separately confirmed bebtelovimab's effectiveness against Omicron as of February 3, 2022.
Previously, bebtelovimab's co-creator AbCellera confirmed on January 9, 2022, this innovative mAbs maintains both full and potent neutralization activity against the Omicron variant and all other known SARS-CoV-2 variants of concern.
Lilly's bebtelovimab authorization request is vital since current demand in the U.S. surpasses mAbs supply.
This availability imbalance was recently increased when two mAbs authorizations were 'Paused' by the FDA on January 24, 2022.
Since September 24, 2021, the U.S. government has distributed over 3 million mAbs.
Eli Lilly and Company is in Indianapolis, Indiana, and recognized U.S. revenue of $1.029 billion from COVID-19 antibodies in the fourth quarter of 2021, compared to about $850 million in 2020.
Lilly's bamlanivimab and etesevimab, administered together, were authorized by the FDA as the first and only neutralizing antibody therapy for emergency use in COVID-19 patients under 12.
In addition, the FDA accepted an sNDA from Lilly and granted priority review for baricitinib for the treatment of COVID-19.
(Excerpt) Read more at precisionvaccinations.com ...
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Omicron?
Isn’t that they one that’s indistinguishable from the common cold?
Some people still get very ill from omicron and BA.2 and BA.3 its two sub lineages. For those people who’s own body either cannot or did not in time develop killer antibodies using an infusion of mAb usually saves their lives. Americans are largely walking comorbidities with an obesity rate over 40% and nearly a 50% hypertension rate for adults over 40 it’s little wonder people still get deathly ill from a bug that targets those health issues. Its a good thing that these mAb retain effect against omicron since it’s going to be around basically forever now that it has reached endemic proportions. The key is getting the mAb before the bug trashes your lungs and then you have a multi month recovery.
At the age of 68 and overwweight I contracted the Fauci/China biological warfare virus and survived it with ease.
I thought it was the ordinary sinus infection that I get once or twice a year and got my usual prescription for amoxicillin.
A few months later when I gave blood again the antibodies showed up when they hadn’t before.
Amoxicillin is a silver bullet, but there is no money in it. I actually got a free prescription of it from a grocery store pharmacy a few years ago.
“ The key is getting the mAb before the bug trashes your lungs and then you have a multi month recovery”
I agree with most of your comments - except two.
Saves lives. 99.7% do not die from covid.
Trashes lungs. The first version of Omicron does not attack the lungs but the upper respiratory. I suspect the same is true for the sub variants.
It is great to have another treatment. Over the next few months I fully expect the supply of treatments will increase substantially.
This is what our screwed up government should have focused on instead of the dangerous and useless vaccines.
In 41 years of infectious diseases practice, I have never seen anyone intubated and requiring mechanical ventilation from a common cold.
It's certainly true that, whereas with delta surging, we would have 13-15 ICU patients, now we have 2-4. That's a good thing.
But it's not a cold.
And I have a friend who is under 40, fit and active was a minor league UFC fighter not overweight or diabetic or hypertension he ended up in the hospital with covid the mAb saved his life he was on 80% assistive O2 and they were debating going to mechanical ventilation eight hours after the infusion he was down to 40% O2 two days later he was down to 6% it took 12 days total for him to leave the hospital. So whats your point covid can and will put fit people in the hospital it just puts more with comorbidities in the ER. Antibodies are a good thing they are exactly what your own body would use to fight a virus cloning the ones proven to kill the bug and then using them is solid science. Few people if any have side effects from antibodies since these are already human antibodies cloned.
I have a close friend that would disagree he got omicron and still struggles to walk up stairs it left all manner of damages to his lungs clearly seen in xrays. While most will present upper respiratory symptoms some people will still progress to lung infections from sars covid II and those people if it progresses too viral pneumonia can and do have lasting damages. There is no way of knowing which group of people a person will be in until they catch the bug. Even if 99.7% survive .3% didn’t have a sniffle and head cold they got it much worse obviously. The point is having a fast acting antibody treatment on tap to help those people who cannot make antibodies themselves such as cancer patients or HIV infection. Or they didn’t make then fast enough to keep the viral replication rate below what their immune system can naturally beat on it’s own. Having the huge influx of killer antibodies to stop the replication and allow the bodies T and B cells to rid the rest of the viri.
In short supply so not available to red states or white people. The usual drill.
At least I don't recall that.
Early treatment is the point.
I started taking amoxicillin on the first day.
Wait three days and you will wind up in the hospital on a ventilator pumped full of Remdesivir for the assisted suicide protocol.
Amoxicillin is an Antibiotic.
That said....I see that and other antibiotics given for COVID...I'm not clear why...Maybe they want to cover that angle...
I've seen now hundreds of chest films..for COVID patients....And they are described as bilateral Pulmonary dence and or / scattered opacities mostly...but can't rule out Pneumonia. Unless they have previous films....If previous films they will confirm something...generally.
This 19 is weird......Makes me think other things......going on.
This is somewhat troubling. If this friend is vulnerable, anybody could succumb. Any ideas why it hit him hard?
Quick! It can be helpful! Outlaw it before it’s to late!
You do not die of the virus.
You die of the opportunistic bacterial infection the virus creates the conditions for.
I have suffered chronic sinus infections my entire adult life and have acquired expertise in surviving them.
It served me so well surviving the Fauci/China biological warfare virus that I did not even know I had it in nyil months later when I gave blood and the antibodies showed up.
Glad you have survived with your expertise knowing your body.
Less frequently, sometimes COVID triggers Cytokine storms directly, does it not?
“bebtelovimab”
Slightly OT, but, where in the HECK do they come up with those names?
It sounds like the name of a lesser demon...
Question 1: Murdered baby stem cell line to test or make?
Question 2: Actually effective?
Question 3: What lying/cowardly scientist is going to tell us this crap is true? Answer: all of them in the media.
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