Posted on 12/13/2021 8:22:37 AM PST by ConservativeMind
In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria—subcellular organelles associated with energy production—which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1). The stimulation of the sympathetic nervous system (SNS) after cold exposure, exercise, and calorie restriction is well known to induce fat browning. Dietary polyphenols may also activate BAT, causing heat to be dissipated from our bodies. BAT activation and white fat browning are thus both therapeutically significant in the fight against cardiovascular diseases and their comorbidities.
A group of scientists examined the browning of fat induced by dietary administration of flavan 3-ols (FLs), a family of "catechin" containing polyphenols abundant in cocoa, apple, grapeseed, and red wine. A new study proved that FLs enhance browning of adipose tissue by activating the SNS. The findings revealed a direct correlation between fat browning and FLs consumption.
The team then used the obtained adipose tissue to investigate the effects of long-term FL treatment. They were thrilled to discover that the white fat of mice who were fed FLs for 14 days eventually turned brown. Some of these cells also had notable structural changes, such as "multilocular phenotype," and appeared to be smaller than normal cells. Scientists showed that Ucp-1 levels, as well as other high temperature-linked proteins, increased in mice fed repeated doses of FLs. Browning markers, referred to as "beige markers" in this study, were also abundant in these mice. "All of these proteins work together to induce the development of the BAT phenotype," exclaims Prof. Osakabe.
Interestingly, this is not the first time FLs have worked wonders. Improvements in glucose and insulin tolerance have been seen after just one dose of FL-rich food administration.
(Excerpt) Read more at medicalxpress.com ...
White privilege!
Lindt 90% dark chocolate bar, only need 0.2 ounces a day.
You left out the wine, but I’ll have that covered.
“Lindt 90% dark chocolate bar, only need 0.2 ounces a day.”
Unfortunately I could only stomach .1 oz/day :).
"They were thrilled to discover that the white fat of mice who were fed FLs for 14 days eventually turned brown"
I think you should take it up with the authors.
"Brown fat did evolved from muscle tissue."
S/b "Brown Fat Evolved....."
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