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> Why is the mRNA vaccine, developed off of the original virus, not effective against Delta? Why don’t we hear about a tweak or modification of the mRNA vaccine to hit Delta? I’m missing something....

Thanks to my doctor I can answer your question. A normal vaccine works by exposing your body to a dead virus. Your RNA takes this and develops a ‘blueprint’ of the virus and provides that to your immune system. Because your RNA came up with this blueprint your immune system knows how to fight it and any variants (up to a point).

With mRNA gene therapy drugs (It’s not a vaccine) that blueprint is provided to your immune system skipping a vital step. Now your immune system has no idea how to deal with any variants, only the virus whose blueprint it is given.

That’s how it was explained to me anyway.

-SB

Hi Snowy, you've got it mostly right.
But I'm afraid it's even worse than that.
In a real infection, viruses are rather sloppy at making copies of themselves, so they make a fair number of mistakes.

So that means, your body sees lots of variations on pretty much the same theme.

And that's the way a real vaccination works, too. It's real virus, so there are lots of slightly different copies, so your body can learn how to recognize a lot of them at once.

But the other thing is -- it's the whole freaking virus, more or less.

So the body gets used to not just slightly different versions, but slightly different versions of all the different parts -- say if it was a car, the doors, the fenders, the headlights, the windshield...and the seats on the inside.

But with the mRNA jabs, the instructions are not from real viruses which make mistakes copying, but from a blueprint. So you don't get lots of different versions. AND, with the mRNA jabs, they're perfect copies, of only 1 part of the virus. Say, if it was a car, the front passenger door. So the body, if faced with a real virus's headlights, doesn't recognize it. Or the fenders. Or the seats. ...and since it's only 1 perfect copy of 1 version of the front passenger door, sometimes, your body doesn't even recognize *that*. Viruses love this. People's bodies, don't.

::::That’s how it was explained to me anyway.::::::

I get all that, but it begs the question: Why don't they take another hack at it a tweak the mRNA to fight the Delta? It's kinda like producing a new formulation each flu season for the flu shot. Why not a new mRNA for Delta?

The mRNA vax was explained to me in football terminology.

The jab teaches the defense (immune system) how to defend against one offensive play: for example, a run up the middle. It then programs the entire immune system to defend against that one play.

If a different play is run by the offense, say a simple out route, the defense jams up the gaps in the middle, leaving the wide receiver open on the sideline --> touchdown.

So any play run other than the run up the middle is going to have success because that's the only play the defense knows how to defend against.

I had assumed successive jabs and boosters would be teaching the immune system to defend against other offensive plays, but I'm not sure if that's how it works.

Proving (?) my initial understanding of the vaxx.
It causes excessive replication of the spike proteins and forces your system to become allergic to said pikes.

You are not immune to the mRNA, you move to “bulk rejection” of any spike proteins.

And, guess what, such “spike” or “attached” proteins mimic the proteins of the Rh factor (clotting).

Note my initial “(?)”, above.

Never bring a clinical/bench-scientist to a clinical/bench-science discussion.
Homie don’t play that, bish.