Posted on 09/14/2021 10:20:20 AM PDT by rxsid
Study Shows Vaccine Will ENHANCE Delta Infectivity
STORY AT-A-GLANCE
COVID-19 jabs continue to be pushed as the only solution to the pandemic, even as “breakthrough” infections increasingly occur. A group of Japanese researchers has also released research showing that the SARS-CoV-2 Delta variant “is poised to acquire complete resistance” to existing COVID-19 jabs like Pfizer and BioNTech’s BNT162b2,1 now being sold as Comirnaty.
What’s more, when four common mutations were introduced to the Delta variant, Pfizer’s mRNA injection enhanced its infectivity, causing it to become resistant. A Delta variant with three mutations has already emerged,2 which suggests it’s only a matter of time before a fourth mutation develops, at which point complete resistance to Pfizer’s jab may be imminent.
The spike protein used in mRNA COVID-19 vaccines consists of the original SARS-CoV-2 spike protein, without mutations. Multiple variants of concern (VOC) have emerged, however, which have numerous mutations and are highly infectious. As mutations increase, so do concerns over vaccine resistance and enhanced infectivity. As the researchers explained in bioRxiv, the preprint server for biology:3
“The receptor binding domain (RBD) of the spike protein binds to the host cell receptor ACE2, and the interaction mediates membrane fusion during SARS-CoV-2 infection.Neutralizing antibodies against SARS-CoV-2 are mainly directed to the RBD and block the interaction between the RBD and ACE2. Most SARS-CoV-2 variants have acquired mutations in the neutralizing antibody epitopes of the RBD, resulting in escape from neutralizing antibodies.”
When a single mutation was added to the Delta spike, most of the anti-RBD antibodies still recognized it. This wasn’t the case with four mutations, however, which the researchers called Delta 4+. Not only was Delta 4+ not recognized, but infectivity was enhanced:4
“… we analyzed the Delta 4+ pseudovirus with four additional RBD mutations. Surprisingly, most BNT162b2-immune sera enhanced infectivity of the Delta 4+ pseudovirus in a dose-dependent manner at relatively low concentrations of BNT162b2-immune sera, but showed weak neutralization only at the highest concentration of the sera.Especially, PFZ7 greatly enhanced the infectivity at relatively low serum concentration. Some sera, such as PFZ13 and PFZ14, did not show neutralizing activity even at the highest concentration of the sera.”
In short, while Pfizer’s COVID-19 jab still neutralized the Delta variant, when four common mutations were introduced to the RBD, the vaccine lost the ability to neutralize the variant and instead enhanced its infectivity.
Although Pfizer-BioNTech BNT162b2-immune sera neutralized the Delta variant, when four common mutations were introduced into the receptor binding domain (RBD) of the Delta variant (Delta 4+), some BNT162b2-immune sera lost neutralizing activity and enhanced the infectivity. This has implications for booster shots on the horizon as well, which are unlikely to be effective.
“A third round of booster immunization with the SARS-CoV-2 vaccine is currently under consideration,” the researchers explained. “Our data suggest that repeated immunization with the wild-type spike may not be effective in controlling the newly emerging Delta variants.”5
Despite the growing recognition that increasing injections may only make matters worse, President Biden said he has spoken with Dr. Anthony Fauci about giving booster shots at the five-month mark after the initial round of injections rather than waiting eight months, as previously suggested.6
A number of experts have raised concerns that COVID-19 jabs and the mass vaccination program could worsen the pandemic by triggering the development of new variants, via a concept known as antigenic, or immune, escape.
A general principle in biology, vaccinology and microbiology is that if you put living organisms like bacteria or viruses under pressure, via antibiotics, antibodies or chemotherapeutics, for example, but don’t kill them off completely, you can inadvertently encourage their mutation into more virulent strains. Those that escape your immune system end up surviving and selecting mutations to ensure their further survival.
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Already, variants have emerged that are showing signs of vaccine resistance. August 30, 2021, the World Health Organization highlighted the mu variant as a variant of interest (VOI), stating it has “a constellation of mutations that indicate potential properties of immune escape.”12
As of August 31, 2021, 39 countries had reported mu cases.13 The lambda variant, which WHO designated as a VOI on June 14, 2021,14 also shows signs of increased infectivity and resistance to vaccines. Writing in medRxiv, researchers from Chile noted:15
“Our results indicate that mutations present in the spike protein of the Lambda variant of interest confer increased infectivity and immune escape from neutralizing antibodies elicited by CoronaVac.These data reinforce the idea that massive vaccination campaigns in countries with high SARS-CoV-2 circulation must be accompanied by strict genomic surveillance allowing the identification of new isolates carrying spike mutations and immunology studies aimed to determine the impact of these mutations in immune escape and vaccines breakthrough.”
As further evidence of COVID shots’ waning effectiveness and the superiority of natural immunity, data presented July 17, 2021, to the Israeli Health Ministry revealed that, of the more than 7,700 COVID-19 cases reported since May 2021, only 72 occurred in people who had previously had COVID-19 — a rate of less than 1%. In contrast, more than 3,000 cases — or approximately 40% — occurred in people who had received a COVID-19 vaccine.16
In other words, those who were vaccinated were 6.72 times — nearly 700% — more likely to develop COVID-19 than those who had natural immunity from a prior infection. Speaking with journalist Daniel Horowitz, pathologist Dr. Ryan Cole explained that natural immunity produces broad immunity that can’t be matched by vaccination:17
“A natural infection induces hundreds upon hundreds of antibodies against all proteins of the virus, including the envelope, the membrane, the nucleocapsid, and the spike. Dozens upon dozens of these antibodies neutralize the virus when encountered again.Additionally, because of the immune system exposure to these numerous proteins (epitomes), our T cells mount a robust memory, as well. Our T cells are the ‘marines’ of the immune system and the first line of defense against pathogens. T cell memory to those infected with SARSCOV1 is at 17 years and running still.”
A retrospective observational study published August 25, 2021,18 also found that natural immunity is superior to immunity from COVID-19 jabs, with researchers stating, “This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity.”
Further, according to a team of researchers from the Washington University School of Medicine, if you’ve had COVID-19 — even a mild case — you’re likely to be immune for life, as is the case with recovery from many infectious agents.19
Unfortunately, health officials aren’t making a distinction for those who have recovered from COVID-19 and continue to recommend injections for all, which may be adding fuel to the fire instead of extinguishing it.
What a flaming dumpster fire these vaccines are turning out go be. Just say no.
“Further, according to a team of researchers from the Washington University School of Medicine, if you’ve had COVID-19 — even a mild case — you’re likely to be immune for life, as is the case with recovery from many infectious agents.19”
the money quote—which jibs with everything we’ve learned about infectious pathogens and and our natural, God given, peak functioning, immune system’s defense against them.
“i believe it does. i know someone who survived covid and then got the shot. i asked why”?
What was their answer?
I also know of someone who recovered and got the shot. Not smart.
Actually, those are facts.
Do you believe that before vaccines appeared, viruses never mutated?
Learn to think.
“Keep in mind natural immunity will prompt mutations as well.”
Yes, that’s why viruses are different now than they were 100 years ago, or even a couple of years ago. But natural immunity militates against the whole virus, and potentially recognize multiple surface features that are unique to it. The more of those features there are, the less likely a mutation would be present that lacks all of them.
The vaccines for Covid all focus on just the spike protein, and, I think, just a single epitope on it. That makes it more likely for a mutation to emerge that evades the immune response.
There were experts who sounded the alarm about this potential before the mass vaccination campaign started. Many of them were censored, condemned, deleted, cancelled etc.
I couldn’t know for sure if this phenomenon will occur or not. It does seem to me that infections among vaccinated are on the rise, leading me to believe that the vaccinated are the super-spreaders of the virus. It is obviously possible both are true - that the mutations are evolving to survive in their hosts, and the hosts unaware and spreading these mutants.
I also kinda figure, since the vaccines never really promised to stop infection or contagion, that the best outcome of mass vaccination would be to reduce the numbers of serious illness and death. I think the powers that be believed this thing would eventually infect almost everyone. But why they bet the entire farm on new vaccines and spent more time and money poopooing research into re-purposing existing drugs that may deliver better outcomes among those infected (or, prophylaxis) than they did researching these potential therapies is anybody’s guess.
Totally predicted by vax experts (not working for vax companies) last year...shocking.
thanks for your extensive post.
I don’t have the brain size to retain your info, but it’s interesting.
For those who believe that Biden’s vaccine mandate is the right thing to do and that he has the authority to do it, let me propose a hypothetical. Assuming Biden is sincere and is looking out for Americans, once the precedent is set, what is to stop a future evil president from mandating a vaccine that will cause death and destruction in order to reduce overcrowding or kill off his political rivals? Did they ever think of that?
Yes, one of the several things few really talk about. This virus can live in many different mammals. It could jump species, mutate, and jump species again and again.
Natural immunity is best overall as the body will learn many ways to attack it - not just by identifying the S-protein. So it can mutate, and those infected and recovered are likely to have broader protection against superficial mutations.
Remember that Dr Faulty referred to these viruses as prototypes?
In the Revelation to John we are told of something to come that will kill a third of mankind … and I’ve occasionally wondered in the last couple of years if there isn’t another bio weapons lab being funded on the sly somewhere along the banks of the Euphrates, anywhere between Turkey and the Red Sea?
Not the way I remember it. I thought they promised the world.
I agree its an opinion.
But sadly it is inevitable. it is simply a numbers game at this point. Mutations happen every time the virus replicates.
Everything being described in the article was common knowledge that folks conveniently “forgot.”
Thank you for the link to the actual study. So many people see a source and think it’s political. Even the CDC is apparently sort of publicly hedging bets and tiptoeing around the government’s shoving boosters up our skins. Vaccines are not the best way to get rid of this.
Having it go through the population to make the species stronger is the way. Some will die; people are simply not meant to live forever. Devastating on a personal level but no one gets out alive, and we all become stronger when we fight off enemies and keep going.
“Keep in mind natural immunity will prompt mutations as well.”
Not nearly as much as “leaky vaccines” do.
They did make that promise, but it was also pretty obvious that they lied. They really hammered that “well, it will reduce your odds of getting very sick from it” a lot more than promising to prevent you from catching it or getting sick or spreading it to others.
They started the entire “misinformation” campaign.
Most of what I read (except many comments from random freepers) tells me the basically same thing. So, I will keep doing the same thing that has worked for me for 18 months.
Quoting you here: “Assuming Biden is sincere and is looking out for Americans, once the precedent is set, what is to stop a future evil president from mandating”: a set percentage of all pregnant women have to get abortions due to overpopulation and climate change caused by same which endangers the planet and everyone on it?
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