Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Study reveals existing drugs that kill SARS-CoV2 in cells (lactoferrin supplement best for safety and common availability)
Science Daily / Proceedings of the National Academy of Sciences ^ | Kelly Malcom / Carmen Mirabelli, Jesse W. Wotring, Charles J. Zhang, Sean M. McCarty, et al

Posted on 08/23/2021 6:53:53 PM PDT by ConservativeMind

Since the beginning of the pandemic, researchers worldwide have been looking for ways to treat COVID-19. And while the COVID-19 vaccines represent the best measure to prevent the disease, therapies for those who do get infected remain in short supply. A new groundbreaking study from U-M reveals several drug contenders already in use for other purposes -- including one dietary supplement -- that have been shown to block or reduce SARS-CoV2 infection in cells.

The study uses artificial intelligence-powered image analysis of human cell lines during infection with the novel coronavirus. The cells were treated with more than 1,400 individual FDA-approved drugs and compounds, either before or after viral infection, and screened, resulting in 17 potential hits. Ten of those hits were newly recognized, with seven identified in previous drug repurposing studies, including remdesivir, which is one of the few FDA-approved therapies for COVID-17 in hospitalized patients.

The team validated the 17 candidate compounds in several types of cells, including stem-cell derived human lung cells in an effort to mimic SARS-CoV2 infection of the respiratory tract. Nine showed anti-viral activity at reasonable doses, including lactoferrin, a protein found in human breastmilk that is also available over the counter as a dietary supplement derived from cow's milk.

"We found lactoferrin had remarkable efficacy for preventing infection, working better than anything else we observed," Sexton said. He adds that early data suggest this efficacy extends even to newer variants of SARS-CoV2, including the highly transmissible Delta variant.

Sexton noted that over the course of the pandemic, other drug repurposing studies have identified different compounds with potential efficacy against SARS-CoV2. "The results seem to be dependent on what cell system is used," he said.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine
KEYWORDS: chinavirustreatment; covid; lactoferrin; nlz; prophylactic; supplements
Navigation: use the links below to view more comments.
first 1-2021-26 next last
Lactoferrin was the best performing for the availability and potential side effects. Lactoferrin is a compound from milk.

It looks promising to just go out and get a bottle of lactoferrin and take a standard dose each day as a potential preventative or treatment.

1 posted on 08/23/2021 6:53:53 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: ConservativeMind

Direct link to the study:

https://www.pnas.org/content/118/36/e2105815118


2 posted on 08/23/2021 6:54:34 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Just ordered some lactoferrin from Walmart. Thanks for the info.


3 posted on 08/23/2021 7:05:02 PM PDT by Dalberg-Acton
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

be careful. Could be planted info of something that doesnt work or mixed with shedded spike protein is unhealthy. Trust nothing at first.


4 posted on 08/23/2021 7:08:21 PM PDT by Democrats hate too much
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind
"just go out and get a bottle of lactoferrin"

*Would it be better to hire a Wet Nurse?

5 posted on 08/23/2021 7:12:50 PM PDT by Deaf Smith (When a Texan takes his chances, chances will be taken that's for sure.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Someone here mentioned this long ago as a possible solution to covid. Cant remember who


6 posted on 08/23/2021 7:13:35 PM PDT by RummyChick (Bagram was the most logical exit point. Stand up and justify your decision (hat tip Larrytown))
[ Post Reply | Private Reply | To 1 | View Replies]

To: Democrats hate too much

Lactoferrin is an extract from whey protein.

I don’t see a downside except it might not help.


7 posted on 08/23/2021 7:14:18 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 4 | View Replies]

To: ConservativeMind; jimjohn
Here is a thread about Lactoferrin for covid from Dec. 5, 2020.

Lactoferrin vs Covid-19: An Anecdotal Report

8 posted on 08/23/2021 7:15:45 PM PDT by TigersEye (Who shot Ashli Babbitt?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Following


9 posted on 08/23/2021 7:19:10 PM PDT by chicagolady (Mexican Elite say: EXPORT Poverty and Let the the Stupid AmericanTaxpayer foot the bill !)
[ Post Reply | Private Reply | To 2 | View Replies]

To: ConservativeMind

Life extension has it on sale


10 posted on 08/23/2021 7:19:27 PM PDT by RummyChick (Bagram was the most logical exit point. Stand up and justify your decision (hat tip Larrytown))
[ Post Reply | Private Reply | To 7 | View Replies]

To: TigersEye; RummyChick

Thank you for that.

I vaguely remembered the one Rummychick spoke of, and I believe you found it.


11 posted on 08/23/2021 7:22:58 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 8 | View Replies]

To: ransomnote; Jane Long

They can’t keep lactoferrin from you!


12 posted on 08/23/2021 7:27:51 PM PDT by Fractal Trader
[ Post Reply | Private Reply | To 1 | View Replies]

To: RummyChick

Someone here mentioned this long ago as a possible solution to covid. Cant remember who


It was probably you!

You had all of the treatments listed, early on.

I still picture your rain suit and goggles.


13 posted on 08/23/2021 7:32:00 PM PDT by Jane Long (America, Bless God....blessed be the Nation.)
[ Post Reply | Private Reply | To 6 | View Replies]

To: ConservativeMind

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390755/

Lots to wade through here. Looks interesting-not sure why we haven’t heard more about it. At least I haven’t.

In Florida we’re at peak- we should be starting to decrease shortly.


14 posted on 08/23/2021 7:34:57 PM PDT by SE Mom (Screaming Eagle mom)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Interesting. Along with the Zelenko protocol and some homeopathic anti-virals we also take bovine colostrum.

Apparently it contains large amounts of lactoferrin.

Could be a contributing factor to our ibitial covid resistance when we received casual exposure and when we did finally get it, a reason our symptoms were so mild


15 posted on 08/23/2021 7:43:03 PM PDT by Mygirlsmom (Back after a long hiatus. Now mygrandkidsgrandma)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

I totally missed it but I stuck the keyword ‘lactoferrin’ on your thread and just for kicks clicked on it to see if it hit any other threads. Just the one.

Thank you for posting this thread.
Gonna get some baby momma milk and give it a try. :)


16 posted on 08/23/2021 7:44:11 PM PDT by TigersEye (Who shot Ashli Babbitt?)
[ Post Reply | Private Reply | To 11 | View Replies]

To: Fractal Trader
They can’t keep lactoferrin from you!

You watch . . . they'll try. . . .

17 posted on 08/23/2021 7:48:07 PM PDT by Chad C. Mulligan (Eleutheromaniac)
[ Post Reply | Private Reply | To 12 | View Replies]

To: Fractal Trader
They can’t keep lactoferrin from you!

Oh, ye, of little cynicism!

Dr. FauXi will announce that mother's milk is more dangerous than Uranium 235 in 3 . 2 . 1 ...

And if you're going to take it against his advice you should at least strain it through two bra cups.

18 posted on 08/23/2021 7:54:39 PM PDT by TigersEye (Who shot Ashli Babbitt?)
[ Post Reply | Private Reply | To 12 | View Replies]

To: Jane Long

Ran across these today, Dry Oxy supplements. Take with water to oxygenate yourself. Normally for athletes and high altitude sports stuff. Basically oxygen pills. These might come in handy if ya get the ChinaFlu.

https://opalinesolutions.com/product/opaline-dry-oxy-capsules-btl120/


19 posted on 08/23/2021 8:15:37 PM PDT by chuck allen
[ Post Reply | Private Reply | To 13 | View Replies]

To: ConservativeMind

bmark


20 posted on 08/23/2021 8:54:50 PM PDT by JABit (Another retired vet.)
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-26 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson