Vitamin D treatment improves your ability to fight off lung infection.
But Vitamin D also increases the expression of ACE2 receptors.
And ACE2 receptors are what Covid spike proteins bind to in order to infect you.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657015/
In our study, 25OHD supplementation was not associated with the severity of COVID-19. On the other hand, a trend toward a 2-fold higher mortality in users was found.
Vitamin D could boost mucosal defenses and protect against infections, and it has been suggested to down-regulate the inflammatory burden contributing to acute respiratory distress syndrome and lung injury, the main cause of death in COVID-19 patients.
Enhanced ACE2 expression is considered a protective factor in acute lung injury. Vitamin D increases the expression of ACE2, and this may apply not only to airway epithelium but also to other organs and monocyte-derived macrophages.
However, ACE2 is the binding site of SARS-CoV-2, and increased ACE2 expression may result in enhanced viral homing and organ damage, as well as in an aberrant innate immune response with hyperactivation of macrophages —perhaps at least in patients with high complication, such as those admitted in our outbreak area.
Our data may appear in contrast with recent literature suggesting that higher serum 25OHD is associated with more favorable COVID-19 outcomes, with lower progression of respiratory illness and to critical illness, as well as lower mortality rates, although no association has been also reported.
However, disease-related inflammation may negatively affect 25OHD metabolism, particularly that of its binding protein, resulting in reduced circulating levels and assessment bias.
It is with this background that we decided to evaluate the association between supplementation rather than serum levels and outcome. Nonetheless, we evaluated serum 25OHD in a subgroup of consecutive patients, demonstrating that supplementation results in substantially higher and adequate circulating levels.
Therefore, although the potential utility of vitamin D in the prevention of respiratory-tract infections is more substantial, its benefits in COVID-19 (prevention and management) still need to be clarified by appropriate intervention trials.
In conclusion, 25OHD supplementation was not associated with hospitalization but appeared to be a risk factor for higher in-hospital mortality in COVID-19.
“to evaluate the association between supplementation rather than serum levels and outcome.”
Interesting.
Seen a study that compared Nitric Oxide levels to D levels and showed a high level of reduced covid infection caused by the NO levels- which were subject to the D levels.
You had better warn Dr Fauci, who says he takes 6000 IU of vitamin D-3 every day, along with a not-yet-revealed amount of vitamin C.
My impression is the big drug companies are terrified of vitamins D & C, which have the potential to drive them out of business, so they subsidize the publication of elaborate lies. Enough vitamin C will apparently cure ANY acute viral infection, as was published in 1949 by Dr Fred Klenner, and never refuted by anyone. Inexpensive nebulized hydrogen peroxide is also highly effective against all upper respiratory infections, including the Wuhan virus, as publicized by Dr Thomas E Levy MD,JD in his free ebook https://rvr.medfoxpub.com/
From YOUR article. Overall, 324 COVID-19 cases were included: 105 in group 1 (PD patients), 92 in group 2 (PD caregivers), and 127 in group 3 (hospital inpatients). The characteristics of the study participants are summarized in Table 1 . The use of 25OHD supplements (mean intake, 58.846 IU/mo) was reported by 38 (11.7%) participants out of 324. Clinical and demographic features of supplement users and non-users were comparable. Serum 25OHD levels of supplemented inpatients (n = 11) were about 3-fold higher than those of non-users. However, among these participants, two had insufficient levels (20–30 ng/mL; range, 24.7–29.4 ng/mL) and three presented a deficiency status (<20 ng/mL; range, 18.0–19.7 ng/mL). Forty-three (21.8%) out of 197 participants with COVID-19 identified through the phone survey required hospitalization, and 47 (27.6%) of hospitalized patients (n = 170) died. The use of 25OHD supplements was not associated with either hospitalization or in-hospital mortality, although a trend toward a 2-fold higher risk of death was found for supplement users, particularly after adjusting for potential confounders (Table 2 ).
11 patients who supplemented with Vitamin D.
2 of the 11 had insufficient levels of Vitamin D in the blood, another 3 were *deficient*. And WTF do these two sentences mean, please?
Forty-three (21.8%) out of 197 participants with COVID-19 identified through the phone survey required hospitalization, and 47 (27.6%) of hospitalized patients (n = 170) died.
...and they neglect to mention in the headlines, this was for Parkinson's Disease patients.
And this disproves that Vitamin D works for the general population?
God, you're a dishonest troll.