Posted on 02/12/2021 9:21:18 AM PST by SeekAndFind
At his news conference Thursday, Gov. Larry Hogan said he hopes the coronavirus vaccine by Johnson & Johnson is approved by the end of February.
The single-dose vaccine would be a game changer and help speed up vaccination statewide, but it’s different than the mRNA vaccines the public has heard so much about from Pfizer and Moderna.
The J&J vaccine is already being manufactured at Emergent BioSolutions in East Baltimore in the hope that the FDA will grant them emergency use authorization in the next couple of weeks, but it’s very different from the vaccines already in circulation.
“I think this is a great time for us to have one more vaccine in our armamentarium,” Dr. Ruth Karron, of Johns Hopkins Bloomberg School of Public Health said.
Doctors are hopeful the J&J vaccine will get FDA approval soon and join the Pfizer and Moderna vaccines in the fight against the coronavirus. The vaccine is different as it doesn't use mRNA like the other two. Instead, it uses adenovirus vector technology.
“The genetic code for the SARS-coV-2 spike protein that's inserted into a virus that's very weakened, it goes into the body and it doesn't stick around for long. It replicates one time and that's enough to allow the spike protein to be expressed and our bodies to develop immunity to it,” Karron said.
The United States doesn't yet have an approved adenovirus vector vaccine, but Karron said the technology is not new, it’s been used at the University of Oxford and in an Ebola vaccine for years.
In clinical trials, the J&J vaccine was 72% effective against mild disease, 85% against severe disease, and importantly, no one was hospitalized or died 28 days after getting the vaccine.
By comparison, the mRNA vaccines proved 95% effective, but Karron said that can be deceiving.
“The J&J vaccine was tested at a time when we had a lot more SARS-coV-2 around than was around potentially when we tested those other vaccines, so in a way it could've been a much more rigorous challenge,” Karron said.
There are some benefits to this vaccine. It only requires only one shot and can be stored at refrigeration temperatures, so it’s much easier to administer. So, bottom line, does it matter which vaccine you get?
“I would say in general it really doesn't matter which one you get, I think it’s wonderful to have in our armamentarium,” Karron said.
Johnson & Johnson said they can deliver 100 million doses of their vaccine to the U.S. by the end of July. And because it’s a one-dose vaccine, that means 100 million people vaccinated.
First off, we have phase 3 data from Johnson & Johnson that was released last week. In the United States it had a 72% efficacy. In Latin America 66%. In South Africa, all the way down at 57%. I don’t think that’s really too surprising considering this new variant in South Africa and Latin America, and this was designed to express the original spike protein. It’s not too surprising to see lower efficacy in South Africa and Latin America than in the United States. Overall, 66% efficacy when you average those three out based on how many people were in each of the areas.
Interestingly, they only looked at moderate to severe COVID-19. The other companies that have released phase 3 data for U.S. studies of Moderna and Pfizer and then BioNTech have all looked at all forms, including the mild form.
I tink Johnson & Johnson was just focusing on the important task at hand, which is to prevent the spread, prevent the infection of moderate to more severe cases. I think that’s probably what they did. But I don’t think they actually came out and explained why they chose not to include mild cases in their analysis as some of the other companies did.
I did see that J&J said that their definition of moderate cases was if a participant had any one of several different symptoms that they had on the list. They didn’t provide that list, at least in the statement that I saw. One of those symptoms would classify someone as moderate. Some of these companies definition of mild to moderate could be different than the next companies.
I’m told this vaccine is developed and manufactured using fetal tissue.
better choice for many
Yes, AstraZeneca and Johnson & Johnson vaccines used the old fetal cell lines to develop and create the vaccine itself, as well as in lab testing.
Don’t want any vaccine for CCP virus. However, if a situation arises where I decide to get one, I think J&J is the one I would receive. Not expecting that to happen, and again, have no plans to get a vaccine and don’t want one.
Well, we know it’s not NO, or Ivermectin, or stage fog, all of which actually kill the virus. Putting vaccination substances in my body that can alter my DNA does not seem a prudent idea.
RE: better choice for many
We must remember this is a single dose vaccine versus two doses for Pfizer, BioNTech vaccine and the Moderna vaccine.
I think the Pfizer vaccine after the first dose is achieved maybe a 52% efficacy or something like that. Johnson & Johnson’s results are significantly better than what we’ve seen from the single-dose of Pfizer.
I think that’s the thing to keep in mind that a single dose vaccine, there’s definitely some advantages and this isn’t necessarily bad efficacy at all for one dose.
The FDA has always said 50% is enough to get emergency use authorization. Certainly anything above 50%, anything above in the 66% range, especially in the U.S. it’s 72 if we don’t start having variants, I think it’s pretty good and certainly going to help reduce the spread. As you’re reducing the spread then that ultimately will help us get rid of the virus.
Is there ANY vaccine that ISN’T using ABORTED BABY CELLS??? DISGUSTING!
Wow, that is a understatement. The word "can" should be "is". By their own words, the vaccines are not vaccines, they do not prevent covid or halt the spread of covid. They only alleviate the symptoms of covid much like NyQuil for a flu. How could it be 95% effective if it doesn't do the very things a vaccine is supposed to do.
None of those vaccines alter your DNA. They do not have any of the genetic elements or protein accessories necessary for them to insert into your DNA.
A virus vector vaccine would, presumably, insert itself into cells at the site of injection. However, your immune system would recognize and attack those cells as part of its response against the vaccine. This is what the immune system does any time it responds to a virus. It attacks infected cells and kills them. I saw a video once of immune cells attacking a virus infected cell and killing it...it was violent and impressive. It looked like the T-cell stabbed the infected cell to death.
I'm thinking that an mRNA vaccine would have similar effect. It also would enter a cell's cytoplasm and force the cell to make proteins (similar to a virus function). The immune system would attack and kill that cell with its foreign proteins.
In any case, the vaccine nucleic acids won't stay around for long.
“armamentarium” Oh, man, I gotta get me one of those!
And if you can't get on of those, maybe you can find one of Nancy Pelosi's quivers.
Any particular reason none of these companies are exploring how to make the vaciine traditionally (whatever that is). Flu vaciine is produced every year. What “technology” is that?
“Well, we know it’s not NO, or Ivermectin, or stage fog, all of which actually kill the virus. Putting vaccination substances in my body that can alter my DNA does not seem a prudent idea.”
There is no way in hell that I will permit anything that is going to screw around with my RNA or DNA to be put in my body.I will take hydrochloquin, zithomycin, and zinc or the Ivermectin. Man is playing around with things he shouldn’t
“Well, we know it’s not NO, or Ivermectin, or stage fog, all of which actually kill the virus. Putting vaccination substances in my body that can alter my DNA does not seem a prudent idea.”
There is no way in hell that I will permit anything that is going to screw around with my RNA or DNA to be put in my body.I will take hydrochloquin, zithomycin, and zinc or the Ivermectin. Man is playing around with things he shouldn’t
Fetal tissue, no problem for the Satanist, secularists, and Athiests. Of course everyone will rush to it even tho, like the other two, “ in the hope that the FDA will grant them emergency use authorization ”. ALL the vaccines are labeled “ experimental “. ....I wonder what happened to all the Christians in America? America seems to be entering judgement. The best part is Biblical history shows that nations are brought to their knees before revival can happen- if it ever does. Buckle up, praise God,keep praying and remember God’s blessings are bestowed daily upon his own.
Just another unapproved experimental product which is not by medical definition or by current U.S. law even a vaccine.
1) It doesn’t cause immunity
2) It doesn’t stop transmission
https://www.bitchute.com/video/amSLD9uxt7yA/
I read on FR that that means 95% better than getting a placebo. And people don’t all get Covid even if they don’t get vaccinated.
Thus, Moderna vaccine was administered to 15,000 people, and the results compared to 15,000 control group. That means that if, say, the control group had 1000 covid cases, and the Moderna vaccine also had 1000 cases, the vaccine didn’t do any good even tho only 1/15 of its group got covid.
But in fact, Moderna only had 11 covid cases - and none of them were hospitalized. That’s “only” 95% better than the control group - but there weren’t any hospitalizations, let alone any fatalities, in the Moderna test group. And even for moderate cases, 11 out of 15,000 is pretty good odds, wouldn’t you say?
I was given the Pfizer vaccine, and its simple “95% effective” number is about the same as Moderna’s. I just hope the numbers behind that percenage are as good as Moderna’s. But beggars can’t be choosers, and anyone who wants the vaccine is a beggar.
“ Any particular reason none of these companies are exploring how to make the vaciine traditionally ”
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Any particular reason prevention and common inexpensive drugs are not being promoted and distributed? Yes there is a reason, money. Pharma has been corrupted and coddled for many years. I refuse to support the corruption and rush job. My elderly mother has been removed from many pharma drugs due to severe side effects, one almost killing her. Think very, very hard before you choose to inject an experimental drug into your body, it is permanent.
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