[numberonepal]

Really, the treatment goal is to prevent the inflammation

Why not use aspirin if inflammation control is the goal? Is it not the "Holy Grail" of anti-inflammatories?

[greeneyes]

Really, the treatment goal is to prevent the inflammation
Why not use aspirin if inflammation control is the goal? Is it not the “Holy Grail” of anti-inflammatories?
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Aspirin lowers a fever. A fever is one of the body’s mechanisms for fighting a disease/virus. Lowering the fever makes you feel better, but there is some thought that it also impedes your immune system’s effectiveness.

Also, it impacts the whole body. A nebulizer treatment is a more focused treatment on the lungs/respiratory area.

[Farcesensitive]

“Why not use aspirin if inflammation control is the goal? Is it not the “Holy Grail” of anti-inflammatories?”

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I believe aspirin can make cytokine storms worse.

[reed13k]

aspirin is a blood thinner. ibuprofen is the anti-inflammatory. as I recall.

[smileyface]

My former employer would love you. You got the message.

Yes, nonsteroidal anti-inflammatory drugs such as ibuprofen and aspirin could be thought to be helpful, but would probably only impact individual points in downstream inflammation related to pain and body temperature; also aspirin has been associated with Reye’s syndrome and other untoward effects.

The inflammatory process is an amplification cascade, much like hemostasis and the clotting cascade (actually the two cascades interact, but that discussion is for another time). Corticosteroids act upstream in the process, are ‘natural,’ and suppress the entire immune process.

[Axenolith]

NSAIDs, including aspirin, apparently are accelerative to to virus. I think it’s along the lines of flu and aspirin in young people causing Reye’s syndrome.

[Bob Ireland]

***Why not use aspirin if inflammation control is the goal? Is it not the "Holy Grail" of anti-inflammatories?***

Not that I have ever heard of. Aspirin can be disruptive to the digestive system - especially for me. Steroids such as dexamethasone are quite powerful in smaller quantities - although they can also disrupt the digestive system. I would think the amount of aspirin to equal the effect of dexamethasone on a cytokine storm would be astronomical.