Italian scientist says she discovered main mechanism behind COVID-19: Annalisa Chiusolo shows how controversial drug Hydroxychloroquine could make people immune to virus

Jerusalem Post ^ | 05/03/2020 | By MAAYAN JAFFE-HOFFMAN

[SeekAndFind]

COVID-19 damages the hemoglobin, impairing the ability of red blood cells to transport oxygen throughout the body, compromising the lungs and resulting in Acute Respiratory Distress Syndrome (ARDS), Italian pharmacology scholar Annalisa Chiusolo explained to The Jerusalem Post.

If her thesis is correct, it would resolve many outstanding questions about the novel coronavirus, such as the greater vulnerability of men – specifically male diabetics – to become seriously ill from the virus, as well as the lower rate at which pregnant women and children contract COVID-19.

Moreover, understanding this mechanism could lead the way to a quicker discovery of the most effective drugs to treat the virus.

Chiusolo is a graduate of the Faculty of Pharmacy of the University of Perugia, Italy, and works as a pharmacist in the European country. Her theory has been published by some of the country’s leading newspapers, including the Italian dailies Il Tempo and Il Giornale.

She told the Post that SARS-CoV-2, the formal name for the novel coronavirus, needs porphyrins for its survival – and probably for its replication – so it attacks hemoglobin, the protein that carries oxygen in the blood, which translates to less oxygen available for the body. The consequence of less oxygen is the accumulation of carbon dioxide.

“The lung cells become the site of the cytokine cascade, an enormous immune response, which is responsible for the acute lung inflammation that characterizes COVID-19 pneumonia,” she said. “The value of hemoglobin in the blood can be an important parameter to assess the SARS-CoV-2 infection: In men the normal value of hemoglobin (Hb) is higher than in women. This would explain the higher incidence of COVID-19 pneumonia in men compared to women, and the lower incidence and better prognosis in children and pregnant women, where Hb values are lower

[wardaddy]

There are two protocols and it comes in 200mg pills and is dirt cheep

One is the malaria prophylaxis which is basically

800 mg first day
600 mg second
400 mg third
And 200 mg each day for four more days

That should be good for two months of more

The other protocol is 200 mg every second or third day

I have a script , TN is not an orange man bad state

Lupus and some arthritis folks take this drug daily for years

All this danger talk is bullshit just to harm Trump

Don’t buy into it

You can easily order it online if you dig around since it’s not a controlled substance ...pay some nurse practitioner online and some pharmacy somewhere will fill it

You can buy about anything today that way except narcotics and adderal and Xanax

The half life is plaquenil is 28 days...lol....imagine Valium was like that...Stupor Nation

[Pelham]

My mother’s primary caretaker has lupus and she’s taken Plaquenil every day for years. Somehow HCQ is supposed to be dangerous while people suffering from a significant autoimmune disease take it daily.

Just like with every drug there will be some people who cannot take it. Ibuprofen and other NSAIDs are dangerous for some people to take.