Posted on 03/30/2020 9:49:20 AM PDT by SeekAndFind
The chief physician executive at Hackensack Meridian Health in New Jersey discussed on Fox & Friends how drugs meant to treat other conditions are now being used to help treat COVID-19 patients.
Anything that might work, it's nice to get out there, Dr. Daniel Varga said on Monday. It's great to use it in emergency situations, use it for compassionate use. Even better to get it out in clinical trials.
Varga made the comments responding to a report where two coronavirus patients in New York City were moved out of the intensive care unit after taking an experimental drug typically used to treat HIV and breast cancer. The patients went from being on ventilators in the ICU to a regular hospital in a matter of days, The Daily Mail reported. Studies reportedly suggest the drug, leronlimab, calms the overly aggressive immune response that could lead to pneumonia and even death.
I don't know the drug personally, but the studies we're seeing is that, like several drugs were trying to use right now in COVID-19, it works predominantly by toning down the immune response that the virus participates in the lung so that the lung doesn't get injured, Varga said.
On Monday, Dr. Varga described three big buckets of clinical innovation during the coronavirus outbreak.
He said the first bucket is figuring out how to optimize standard care.
One of the things were seeing in people who have to get ventilated because of COVID-19 is this use of whats known as prone ventilation, where you actually lay the patient on their belly while they are ventilated, Varga said. What it tends to do is lets the lungs expand more easily so you can get more oxygen down into the lungs and that's been a really big asset
(Excerpt) Read more at foxnews.com ...
MUST INCLUDE ZINC!
ZINC is the cure, Hydroxychloroquine is the vehicle and azithromycin (the LEAST important part) is to help prevent OTHER BACTERIAL (NOT viral) infections.
So, ZINC is the miracle cure. Hydroxychloroquine just lets Zinc do its job far better.
No, Im not a doctor and I dont play one on the Internet, BUT Dr. Vladimir Zelenko is and does.
https://www.youtube.com/watch?v=1TJdjhd_XG8&t=586s
” We use it for our intubated patients for the most part.”
TOO LATE!
HALF (50%) of those people will die anyway.
Start treating people as soon as symptoms appear or they get a positive test result. (100% cure rate).
https://www.youtube.com/watch?v=1TJdjhd_XG8&t=586s
RE: Start treating people as soon as symptoms appear or they get a positive test result. (100% cure rate).
________________________________________
I looked at the study from Dr. Didier Raoult ( the first and second one he published, the second study with 80 patients ).
The advantage of hydroxychloroqine is its potential reduction in length of stay of Covid-19 positive patients who are not that severely ill, reducing the burden on the hospitals. THIS IS STILL SIGNIFICANT!
But I also want to see lives saved !
I hope it also helps in significant reduction in mortality (especially for the very ill, e.g. on ventilators ), but widespread usage still needs to prove that.
Now, if as you suggest, we are going to give this to every single Covid-19 positive person with symptoms, how many people would we need to give the drug to?
RE: The Daily Mail reported. Studies reportedly suggest the drug, leronlimab, calms the overly aggressive immune response that could lead to pneumonia and even death.
Well, Dr.William Grace said the same thing of hydroxychloroquine. It modulates the over reactive response of the body’s immune system to Covid-19.
The question is this -— which one does it better at a cheaper price? leronlimab, or hydroxychloroquine?
I have the impression that most of these biologics ending in "mab" run on the order of $3K per month and I suspect that there is limited production capacity. So hydroxychloroquine should be much more attractive in a pandemic, unless you are a Big Pharma company.
Whoa big shifter. one person on the internet claiming something does not equate to 100% cure rate. All potential treatments should be looked at and studied. We do not want to miss the best treatment chasing after something that one person claims on the internet when he was treating anyone with the sniffles
unless the biological has a clear treatment advantage. How do we find this out? randomized double blind studies
You are right you are not a doctor and the other guy plays a doctor on the internet. We need hard data on the best treatments. if everyone picks all their eggs in the unproven hydroxychloroquine basket we might just speed right by the real treatment
We’ll have some good evidence by weeks end.
True - and that may take 3-6 months. Definitely worth doing, but what do we do in the meantime?
From all the literature I’ve seen to date, and admittedly I have no more access to anything than the common joe and am not an MD.. but the survival rate once Intubated is low... something like 15-20%... and I could be wrong, but I don’t think anyone over the age of 70 has recovered once intubated maybe not anyone over 60 worldwide of this to date.
Seems to me compassionate measures should be kicking in before Intubation in critical cases... given the low survivability rates once folks are.
If those survival rates don’t improve, it seems like all that is being done is prolonging of suffering for many people being intubated... a week or two, gasping for breath, with no one you know even around you for weeks before you finally succumb to organ failure due to the lack of oxygen.
Please someone correct me if I am wrong about recover of elderly once intubated.... Because I would love to be told I am wrong on this.
From all the literature I’ve seen to date, and admittedly I have no more access to anything than the common joe and am not an MD.. but the survival rate once Intubated is low... something like 15-20%... and I could be wrong, but I don’t think anyone over the age of 70 has recovered once intubated maybe not anyone over 60 worldwide of this to date.
Seems to me compassionate measures should be kicking in before Intubation in critical cases... given the low survivability rates once folks are.
If those survival rates don’t improve, it seems like all that is being done is prolonging of suffering for many people being intubated... a week or two, gasping for breath, with no one you know even around you for weeks before you finally succumb to organ failure due to the lack of oxygen.
Please someone correct me if I am wrong about recover of elderly once intubated.... Because I would love to be told I am wrong on this.
5. He fails to mention prone ventilation. Anyone who is serious would probe a patient well before a PEEP of +25
Question is, which is the more effective for most people? the lesser effective can be used when the primary fails... Remember, we are talking about medicine here folks, there is natural genetic diversity, even if something works on 99% of the people there will still be that 1% it will not... no matter what you do. Having more than one option is a good think...
Which ever is most effective is used first, when that fails, other options are tried.
The “nice” think about this, if you can say any nice, is that it is the suppression ion of the immune response that is allowing survival, not an antiviral or antibiotic, that the virus could mutate and become immune to.
If these drugs do help these patients, in the large scale, they can be used for other things that cause such reactions in people, nut just the Kung Flu.
the same thing we are doing now. throw the kitchen sink at it but dont neglect to do the studies.
Vitamin C is by far the cheapest anti-inflammatory. One caution, if you use high dose C you should taper down dose over about a week. I commented the following at a discussion regarding why certain off patent, off label uses were being downplayed by media doctors and press.
No, a potential cure might not be discussed by either Democrats or Republicans. For example, the fact that NY is now trying Vitamin C to treat Covid-19 sufferers was not mentioned, and you can be sure none of the doctors such as Fauci and others have mentioned it in public even though China has three clinical trials at work, which unfortunately will not be reported until Sept. Below explains why I no longer belong to either party.
While Democrats might wish to deprive Trump of any credit for helping this scourge, both parties are subject to the political donations and pressures of Big Pharma. These established treatments for other illnesses are off patent, and therefore no longer BIG money makers for the drug companies. On the other hand from their perspective Vitamin C is even worse. I checked lower cost chloroquine at GoodRX. It was $75.00 for 30 500mg tablets. The same quantity of Vitamin C tablets costing from 5 to 10 cents each would be $1.50 to $3.00. Wow!! No fortunes to be made there, for sure. And C is well known as completely safe.
New York is now reported to be using Vitamin C for treatment. https://nypost.com/2020/03/24/new-york-hospitals-treating-coronavirus-patients-with-vitamin-c/
This is good news, but they are still using doses far less then those by Dr. Cathcart in his high C treatment of 9,000 patients over 10 years. He recommends pushing C to bowel tolerance. His link below is long, and very informative regarding how to treat a number of conditions. http://www.doctoryourself.com/titration.html
A Chinese doctor has transmitted good news about Vitamin C treatment, but points out at the video that NY is not using strong enough doses.
https://greenbeltoutdoors.com/blogs/survival-blog/vitamin-c-in-high-doses-is-safe-in-treatment-of-coronavirus-covid-19-dr-richard-cheng
Should you have any medical or military deciders, or even President Trumps office you want to contact with the above, here is the official NIH description of at least one of the Chinese studies.
https://clinicaltrials.gov/ct2/show/NCT04264533
When my son in Special Forces said the World Health Organization (WHO) was asking Google and Facebook to suppress some videos on China and Vitamin C, I was surprised. I am no longer a skeptic. So, I hope the skeptics here will be willing to consider my own recommendations based on over 45 years helping myself, my family, and others, some in deadly peril. To parallel Dr. Zelenkos advice format. In addition to meds he suggested if you can find and trust them,
1. Any person of any age not yet sick and living where infection is possible:
1 gram (1,000 milligrams) of Vit. C morning and evening.
2000 to 4000 IU of Vitamin D per day, Vitamin K2
1 good multi-vitamin/multi-mineral morning, and evening if under stress or chronically tired, continue when sick
1 or 2 calcium/magnesium/zinc tablets a day, continue when sick
Other supplements you have researched and find sensible for your physical age and condition
2. Any person in the high-risk category even with minor symptoms
2 grams C in the morning, 1 or 2 gms. every 5 hours, 2 gms at bedtime
Continue use of other supplements, drink plenty of water
3. Any person with serious symptoms if they are not hospitalized
Continue with step 2 recommendations
Crush 10 grams of C or equivalent of powdered C and add to 12 to 20 ounce bottle of water
Have patient sip the water as they wish to level of bowel tolerance, see Cathcarts link above
Allow C water bottles as often as every 6 or 8 hours
A tablespoon of honey and 1/2 teaspoon garlic powder or juice can be added to water bottle
4. For serious case try to find doctor/hospital that will use IV high dose Vitamin C if you want it. If not, sneak in the water bottles if not intubated.
In my experience, using number 2. Vitamin C doses would reduce a fever by 2 degrees: 104f to 102, 103 to 101. Using honey makes it easier to take the acidity of the C, the garlic I found especially good for the dry choke phase of a cough. Do not use unpasteurized honey for a child under 1 year. When very young and sick, I would fill a baby bottle with water, add 500mg of crushed C, a tablespoon of honey, and 1/4 teaspoon of garlic powder, mixed well. They would wake crying or coughing, grab the bottle, suck on it and fall back asleep. C also opened drainage for ear infections. Good luck and please send this information to anyone who can use it or encourage authorities to look into it.
This looks like one of those drugs where "if you have to ask, you can't afford it".
CytoDyn is expected to price leronlimab at a similar price to its main rival, Trogarzo (ibalizumab; Theratechnologies/TaiMed Biologics), which commands an exceptionally high annual list price of approximately $118,000 per patient.
I'm sure a larger patient pool would bring that down some and you might only need a fraction of the amount a cancer patient uses, but it isn't cheap...
RE: Vitamin C is by far the cheapest anti-inflammatory. One caution, if you use high dose C you should taper down dose over about a week.
OK, how many mg. should a CoVid-19 NEGATIVE person take per day?
RE: Vitamin C is by far the cheapest anti-inflammatory. One caution, if you use high dose C you should taper down dose over about a week.
OK, how many mg. should a CoVid-19 NEGATIVE person take per day?
Link on Vitamin c usage
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