Posted on 10/14/2019 10:45:03 AM PDT by BenLurkin
In the 1950s, researchers stumbled upon a new class of drugs that provided relief for those suffering from schizophrenia. These drugs were known as antipsychotics and, as the name suggests, they reduced symptoms like hallucinations and delusions primarily by reducing the levels of dopamine in the brain. This led clinicians and scientists to argue that dopamine was linked to the experiences of psychotic symptoms, and a concerted research effort ensued, seeking to solve the puzzle of why excess dopamine might produce hallucinations.
Although it was later shown that increasing dopamine could produce hallucinations, establishing a consistent link between them, it has not been clear why.
They achieved this by taking advantage of a simple fact: Your brain is lazy. It makes shortcuts to understand the deluge of information that bombards it daily. If youre presented with consistent information, consistently, your brain adjust its expectations of reality in turn. This is the basis of Bayesian theories of how we perceive the world that is, the brain makes inferences about the world around us based on statistics and probabilities on what is likely to occur.
[I]ncreasing dopamine made it more difficult for participants to adjust their perception an effect comparable to how the hallucinators had struggled. Moreover, the extent to which participants struggled was strongly associated with the severity of hallucinations but not with any diagnosis of schizophrenia. In other words, the difficulty appeared to be associated with a symptom, not a diagnosis.
Using brain imaging, the researchers also showed that an increased capacity for dopamine release, from a part of the brain known as the striatum (an area involved in schizophrenia), was associated with the severity of hallucinations. Together, these experiments showed that excess dopamine was associated with difficulty in accurately predicting reality.
(Excerpt) Read more at inverse.com ...
Such a cute baby.
I love the coats that look like you could sink your fingers deep in them. Of course you couldn’t: you’d lose your fingers!
Well, you do have ten....
True. As I sometimes observe in a different context, “It’s okay: I have other sons.”
That’s the spirit!
Nature is into redundancy ;-).
The Spanish choir will be celebrating our percussionist’s birthday at practice today. I need to start draining fruit for my popular fruit salad, which contains mixed fruit and whipped cream.
Well-drained fruit is the secret. There’s never any left over. I lost your recipe two laptops ago. Cats.
A happy birthday practice to all involved!
Several cans of fruit, drained. Tub of whipped topping, thawed. Mix.
And you’re right, well-drained fruit is the key. It would have been better if I’d drained it last night, but I went to bed before 8:00.
What a sweet little Floofy face!
Good morning.
Last night was interesting. I got there, first, of course, and got a table for six, (as it turned out, we would never have fit into a booth) and the place was small but it filled up very quickly. One of the ladies at our table was 91 and the other was 70, and they were interesting.
I was slightly dreading trying to broach the subject of CFIDS and why it was so important to keep to a schedule, when the lady beside me asked me what I had, meaning, the thing that kept me from evening appointments. So I explained. When I was done, Carol said that from now on, we should go to lunch, rather than dinner.
The food was excellent! I was trying to decide on a mushroom burger or a cheese burger, and I opted for the cheeseburger because it was available on the “Senior Menu.” Oh, it was sooooo yummy!
It was 1900 before I was finally able to shut the light off, but I just lie there in the dark and ground my teeth while the rest of my muscles didn’t want to relax. *sigh*
Still it was a good evening. We didn’t linger because people were standing in the doorway wait for a table.
I like the recipe my late brother gave me in the 80’s...
Crushed pineapple, Jell-O, cottage cheese and whipped cream.
I like it with orange Jell-O but a lot of my family likes it with strawberry. I haven’t made any for a long time. I should, though. :o]
I don’t like to put cottage cheese in stuff. Too much like brains!
I’m glad you had a better time last night than you expected. And how considerate of your hosts to accept your explanation of your health limitations. I keep saying that it should be a simple “Love your neighbor” matter to recognize that we all have issues, especially as we get older, and trading dinner for lunch should be a no-brainer.
But what do I know: I never go anywhere but Envirothon, choir, and committee meetings!
Elon danced at the Chinese Gigafactory. They've become productive in record time.
But his reason for dancing most recently is the fourth-quarter sales results for Tesla. They've done well.
Likely the reason for dancing next year will be similar results, and a successful inauguration of communications on Starlink, and a successful re-entry test for Starship.
Elon Musk is being Tony Stark. It's good to be Tony Stark.
If this were anyone but my son’s in-laws, I would politely decline every offer, bar none. But since the event on the 11th of last month, they have “adopted” me.
My other “outings” are church, medical and errands. Period. It’s the only way I can keep the symptoms at bay. By strictly staying on a schedule, I’m able to enjoy the time I spend out of the house and not worry about whether or not I’ll get sick before I can make it back home.
If a few of my sons go to Mars, Earth will be safer, until they develop the mass drivers.
More of a statement than an actual threat, but yes; something to keep in mind.
I feel I owe it to humanity to mention the concept.
"I spewed on the carpet. I dare you to say anything."
Kitteh is not judging you on your willingness to clean up spew. Judging instead on your ability to provide more places for spewing! ;o]
Good morning.
Well, the night was fairly good, I think. Nine hours, but I’m still tired. *yawn* Same ol’ stuff, I guess so I’ll shut up.
I have more letters to write. Seems I never get done with it. *sigh* I’ll shut up about that, too! LOL!
That’s such a cute little Morning Floof! Makes me wish I had one.
Good morning. I think Jake ate something dead. He spewed last night - looked like a whole bowl of food - and then there were two heaps this morning when I got up. All on the carpet, of course.
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