Posted on 10/14/2019 10:45:03 AM PDT by BenLurkin
In the 1950s, researchers stumbled upon a new class of drugs that provided relief for those suffering from schizophrenia. These drugs were known as antipsychotics and, as the name suggests, they reduced symptoms like hallucinations and delusions — primarily by reducing the levels of dopamine in the brain. This led clinicians and scientists to argue that dopamine was linked to the experiences of psychotic symptoms, and a concerted research effort ensued, seeking to solve the puzzle of why excess dopamine might produce hallucinations.
Although it was later shown that increasing dopamine could produce hallucinations, establishing a consistent link between them, it has not been clear why.
They achieved this by taking advantage of a simple fact: Your brain is lazy. It makes shortcuts to understand the deluge of information that bombards it daily. If you’re presented with consistent information, consistently, your brain adjust its expectations of reality in turn. This is the basis of Bayesian theories of how we perceive the world – that is, the brain makes inferences about the world around us based on statistics and probabilities on what is likely to occur.
[I]ncreasing dopamine made it more difficult for participants to adjust their perception — an effect comparable to how the hallucinators had struggled. Moreover, the extent to which participants struggled was strongly associated with the severity of hallucinations — but not with any diagnosis of schizophrenia. In other words, the difficulty appeared to be associated with a symptom, not a diagnosis.
Using brain imaging, the researchers also showed that an increased capacity for dopamine release, from a part of the brain known as the striatum (an area involved in schizophrenia), was associated with the severity of hallucinations. Together, these experiments showed that excess dopamine was associated with difficulty in accurately predicting reality.
(Excerpt) Read more at inverse.com ...
Thanks! I learn something new every day, and this was an unexpected jewel!
I learned it today too. Like ArGee, I always assumed it was Latin-ish nonsense.
Wow. Twins! Whodathunkit?
You called?
Triplets, if ArGee goes to the link...
Well, that’s what I was taught when I worked for a magazine. And that’s how we used it.
Well, look what the cat dragged in (or at least caused to comment).
Howdy!
And that is how it’s used. But that it’s derived from real Latin? Who knew?
You’re welcome.
LOL!!!
Someone ratted me out! :o])
Not me, not this time.
My bad...
A reasonable guess
1234?
Looks good.
Got it!!
Well now. This is a fine pickle..
Seems that the well pump has expired.
Have voltage at the circuit breaker, voltage at the wall mounted disconnect, voltage on hot side of pressure switch, and voltage on the load side of the pressure switch. Any further tracing leads down the rabbit hole, er, well hole, er whatever..
And no water pressure so pump is obviously falling down on the job. I have no idea the age of the well pump but if it was installed when the lawyer owned the place it’s at least 30 years old..
And now phone calls to well pump people yields only answering machines - so far.
Got plenty of snow to melt though. As if that’s a consolation..
Been there, done that. Quite recently, in fact.
Toilets can be flushed with as little as a full gallon of water if it is poured vigorously directly into the bowl.
During an extended period of no electricity at my house many years ago, I placed two large plastic garbage bins in the bathtub, and kept them filled with rainwater or meltwater from the roof), for the purpose of flushing the toilet.
At that time, I scavenged up a pressure tank, drove down to my cousin’s house, and with his permission filled up the tank from a garden hose, (pressurizing it at the same time).
This, when connected to my outside faucet, gave me pressurized water in the house for cooking, washing hands, and other carefully metered usage.
My heat was supplied from a wood stove.
Eventually, I got the electricity back in order, but this time of supposed privation had turned out to be a remarkably peaceful one.
You can buy a replacement pump at a home supply store such as Ace Hardware, Lowe's, or Home Depot.
But pulling a well is a chore for a couple of younger men.
Which is why I'm 'contracting out'... ;-)
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