Beware Of Eating Grapefruit With Any Of These 32 Common Drugs

BI ^ | 3-20-2017 | Dr. Matthew Thorpe, MD, PhD, Authority Nutrition

[blam]

Note: This article contains general information — not specific medical advice. Talk to your physician before changing your use of any medication.

Grapefruit is a delicious citrus fruit with many health benefits.

However, it can interact with some common medications, altering their effects on your body.

If you're curious about the grapefruit warning on many medicines, this article will help you understand why it's there and what your options are.

Here's a closer look at 32 common drugs that may have dangerous interactions with grapefruit.

How does it interact with medications?

How does it interact with medications?

Medications are processed in your liver and small intestine by a specialized group of proteins called cytochrome P450 (CYPs).

CYPs break down medications, reducing the blood levels of many of them.

Grapefruit and a few of its close relatives, such as Seville oranges, tangelos, pomelos and Minneolas, contain a class of chemicals called furanocoumarins.

Furanocoumarins disrupt the normal function of CYPs. In fact, studies show that they increase the blood levels of over 85 medications (1).

By slowing down the way in which CYPs normally break down medications in your gut and liver, grapefruit can increase the side effects of these drugs (1).

There are three things to know in order to understand if and how you can safely consume grapefruit with these medications.

1. It doesn’t take much: One whole grapefruit or one glass of grapefruit juice is enough to alter how these medications affect you.

2. It lasts several days: Grapefruit’s ability to affect medication lasts for 1–3 days. Taking your medication a few hours apart from consuming it isn’t long enough.

3. It’s significant: For a small number of drugs, grapefruit’s effects can be serious.

(snip)

[RushIsMyTeddyBear]

Bkmrk. Love Ruby Red.

[RushIsMyTeddyBear]

.......With seltzer for a bit of fizz.

[V K Lee]

this fruit is NOT to be eaten by those on warfarin (COUMADIN) as well. No Grapefruit, no cranberry sauce, no green leafy vegetables - ie. lettuce, broccoli

[SkyDancer]

Just saying - anyway that garbage they sell in supermarkets is not juice but a juice cocktail. Even the label is misleading stating “pure juice” ... well yeah, you want cranberry juice? Well it says right there on the label “pure juice” and the second two ingredients are apple and grape followed by cranberry and loaded out with corn syrup with the secondary juices added to fill the bottle. I hate that. Better to take a cranberry pill or a grapefruit pill if you’re so inclined.

[libertarian27]

If your grocery stores carry Polar Sodas/Seltzers
try their Pink Grapefruit Dry Soda ( and seltzer too) they're spectacular!
(I mix them 1/2&1/2)

[freeonefrom]

A to Z
Albendazole
Amiodarone
Apixaban
Atorvastatin
Bupropion
Buspirone
Clopidogrel
Colchicine
Diazepam
Dronedarone
Eplerenone
Erythromycin
Felodipine
Fentanyl
Losartan
Lovastatin
Lurasidone
Midazolam
Nifedipine
Oxycodone
Primaquine and related antimalarial drugs
Quetiapine
Rilpivirine and related HIV drugs
Rivaroxaban
Sildenafil
Silodosin
Simvastatin
Tadalafil
Tamsulosin
Ticagrelor
Triazolam
Ziprasidone

Thanks

[right way right]

Mmmmm, it taste like bile so everythng tastes better after after you drink the juice.

[Phil DiBasquette]

[Hootowl]

Oh, rats! I love grapefruit and two of my meds were on the list. Bye bye, beloved fruit! Sob!

[RushIsMyTeddyBear]

I will! Thanks!

[MurrietaMadman]

Oxycodone boost. Bet nobody was told about grapefruits and oxycodone.

[Old Yeller]

What is the effect of grapefruit on sildenafil? (viagra...)

Hard to say.

[sheana]

I drink a glass of ruby red grapefruit juice every morning with breakfast. Not on any drugs it interferes with.

[BobL]

It would sure be nice if they could figure out this crap BEFORE they prescribe it to millions of people.

But glad to hear things are going well with you!!

[Harmless Teddy Bear]

There are pure cranberry juices out there but they are best when mixed with something else.

Pure unsweetened cranberry juice is a bit tart and strong.

As for grapefruit why not just eat the grapefruit? Providing you are not taking one of the medications on the list.

[Does so]

Eat grapefruit. Skip the drugs.

There might be more to what you wrote than you think!

[SkyDancer]

I guess I'll have to go to what's called a whole foods market to get pure cran. juice - pappy sez vodka would mellow it out. LOL

I like fresh grapefruit but don't eat it very often.

[Harmless Teddy Bear]

I get it at the mega-lo-mart, Lakewood brand.

[PraiseTheLord]

And not just grapefruit, can be cranberry juice or other.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Also Valencia oranges — they say.

This has been common knowledge for ?years.

Read www.PeoplesPharmacy.com -— get on their mailing list.
— email new info twice a week.

[cpdiii]

Oddly enough a reasonably accurate article. Listen to you pharmacist. He knows!