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Study Finds Evidence of Genetic Response to Diet
NY Times ^ | September 10, 2007 | NICHOLAS WADE

Posted on 09/09/2007 7:48:53 PM PDT by neverdem

Could people one day evolve to eat rich food while remaining perfectly slim and svelte?

This may not be so wild a fantasy. It is becoming clear that the human genome does respond to changes in diet, even though it takes many generations to do so.

Researchers studying the enzyme that converts starch to simple sugars like glucose have found that people living in countries with a high-starch diet produce considerably more of the enzyme than people who eat a low-starch diet.

The reason is an evolutionary one. People in high-starch countries have many extra copies of the amylase gene which makes the starch-converting enzyme, a group led by George H. Perry of Arizona State University and Nathaniel J. Dominy of the University of California, Santa Cruz, reported yesterday in the journal Nature Genetics.

The production of the extra copies seems to have been favored by natural selection, according to a genetic test, the authors say. If so, the selective pressure could have occurred when people first started to grow cereals like wheat and barley at the beginning of the Neolithic revolution some 10,000 years ago, or even much earlier.

Paleoanthropologists have long wondered what change in the usual primate diet of fruit and nuts enabled the emerging human lineage to support a brain that eventually swelled to three times the size of chimpanzees’.

Neural tissue requires large amounts of energy, and the usual assumption is that humans began to eat meat some 2.5 million years ago when brain volume started to expand. But another possibility is that the extra nutrients came from starch...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: copynumbervariation; diet; genetics; godsgravesglyphs; heredity; nutrition
Perry GH, Dominy NJ, Claw KG, Lee AS, Werner J, Villanea FA, Mountain JL, Misra R, Lee C, and Stone AC. Diet and the evolution of amylase gene copy number variation among human populations. Nature Genetics (in press)

That appears to be the title and authors, but I can't find a link even to the abstract anywhere.

1 posted on 09/09/2007 7:48:56 PM PDT by neverdem
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To: neverdem

Epigenetics at work.


2 posted on 09/09/2007 8:00:09 PM PDT by Maelstorm (Understanding the motivations of a victimizer does not exonerate them.)
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To: neverdem
People in high-starch countries have many extra copies of the amylase gene which makes the starch-converting enzyme...

Want to eat all the pasta you want and look like Twiggy? Move to Italy.

3 posted on 09/09/2007 8:07:44 PM PDT by Rudder
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To: Maelstorm
Epigenetics at work.

That's another phenomena. They're finding copy number variation in the genes here.

It's non Mendelian genetics. That's a paper on it from Nature.

4 posted on 09/09/2007 8:15:30 PM PDT by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: Maelstorm

And here I thought we were all evolving to be lard asses. Silly me.


5 posted on 09/09/2007 8:17:24 PM PDT by rbg81 (DRAIN THE SWAMP!!)
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To: neverdem

There is a book called “Cook Right for Your Blood Type”
1999 Dr. Peter J. D’Adamo
Based on ancestoral eating habits passed on through blood type.


6 posted on 09/09/2007 8:24:29 PM PDT by Cold Heart
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FReepmail me if you want on or off my health and science ping list.

7 posted on 09/09/2007 8:26:13 PM PDT by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: neverdem; martin_fierro; blam; StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 24Karet; ...

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Thanks neverdem. Martin -- pingworthy?

Just adding to the catalog, not sending a general distribution.

To all -- please ping me to other topics which are appropriate for the GGG list.
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8 posted on 09/10/2007 7:37:04 AM PDT by SunkenCiv (Profile updated Wednesday, August 29, 2007. https://secure.freerepublic.com/donate/)
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To: Cold Heart

That must be why I love matza and venison. Sometimes its confusing to be a Texan descended from Polish Jews and Commanches. Do I shoot ‘em, scalp ‘em, or sue ‘em?


9 posted on 09/10/2007 10:02:19 AM PDT by darth
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To: neverdem

“Paleoanthropologists have long wondered what change in the usual primate diet of fruit and nuts enabled the emerging human lineage to support a brain that eventually swelled to three times the size of chimpanzees’.”

Perhaps we emerged by some other means???? Just sayin’....


10 posted on 09/10/2007 11:24:41 AM PDT by Rennes Templar ("The future ain't what it used to be".........Yogi Berra)
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To: neverdem

This does not appear to be an actual scientific paper.


11 posted on 09/10/2007 11:35:18 AM PDT by RightWhale (It's Brecht's donkey, not mine)
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To: RightWhale
This does not appear to be an actual scientific paper.

Diet and the evolution of human amylase gene copy number variation

It's a pdf link to the article. I'm glad that I found your statement. It appears to just be a delay of some sort. IIRC, I tried every way I could to find the abstract at the time. Some papers don't have abstracts. Here's a PubMed link to the abstract:

Diet and the evolution of human amylase gene copy number variation.

12 posted on 09/28/2007 2:40:49 PM PDT by neverdem (Call talk radio. We need a Constitutional Amendment for Congressional term limits. Let's Roll!)
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To: neverdem

It’s Nature and it’s Letters. Be interesting to see if it makes it to a more formal scientific journal.


13 posted on 09/28/2007 2:46:01 PM PDT by RightWhale (25 degrees today. Phase state change accomplished.)
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