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Study: Single injection of protein could reverse symptoms of Type 2 diabetes
Fox News ^ | July 17, 2014 | FoxNews

Posted on 07/17/2014 6:13:02 AM PDT by Innovative

When mice with the human equivalent of Type 2 diabetes were injected with the protein FGF1, their blood sugar levels returned to normal over two days. Just one injection of the protein both regulated these levels and even helped reverse insulin insensitivity – the underlying cause of diabetes.

Published in the journal Nature, the research on FGF1 could revolutionize diabetes treatment.

In addition to being effective against diabetes, the protein has several advantages over current diabetes drugs. It does not result in dangerous side effects seen with other diabetes drugs, such as heart problems, weight gain, or hypoglycemia. Additionally, FGF1 not only increased insulin levels but also helped the mice regain their own ability to regulate insulin.

(Excerpt) Read more at foxnews.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: bloodsugar; diabetes; discovery; glucose; health; insulin; medical; medicine; proteininjection; type2
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To: dangerdoc
No such thing as Big Pharma. If one company can bring a drug that will run its competitors out of the market they will. If another company can make something similar, they will claim their version is superior and try to take all the business from the first company.

You incorrectly assume each Pharma has control over their product availability. The FDA is in control, and the FDA has a long record of burying good products. The really big Pharma control the FDA.

Unfortunately, scientists have cures for many problems in mice. In 2008, there was a Canadian study which found the following:

Diabetic mice became healthy virtually overnight after researchers injected a substance to counteract the effect of malfunctioning pain neurons in the pancreas. "I couldn't believe it," said Dr. Michael Salter, a pain expert at the Hospital for Sick Children and one of the scientists. "Mice with diabetes suddenly didn't have diabetes any more."

They injected the neuropeptide "substance P" in the pancreases of diabetic mice, a demanding task given the tiny size of the rodent organs. The results were dramatic. The islet inflammation cleared up and the diabetes was gone. Some have remained in that state for as long as four months, with just one injection.

41 posted on 07/17/2014 9:06:38 AM PDT by aimhigh (1 John 3:23)
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To: aimhigh

I agree, the FDA moves too slowly. But on the other hand, they have cured about every disease known to man in mice and rat models. Those same treatments frequently are ineffective when tried on humans.


42 posted on 07/17/2014 9:19:49 AM PDT by dangerdoc ((this space for rent))
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To: Innovative

Won’t be of much use as high fructose corn syrup is in nearly everything.


43 posted on 07/17/2014 9:41:58 AM PDT by minnesota_bound
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To: Innovative

bfl


44 posted on 07/17/2014 10:02:59 AM PDT by AllAmericanGirl44
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To: FatherofFive

“Type 2 diabetes is completly preventable and completly treatable with diet and exercise.”

No.


45 posted on 07/17/2014 10:30:55 AM PDT by dsc (Any attempt to move a government to the left is a crime against humanity.)
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To: null and void

This is good news!



BE A DEAR AND
SEND MONEY HERE!


46 posted on 07/17/2014 10:31:10 AM PDT by Lady Jag (Tolerance and apathy are the last virtues of a dying society. - Aristotle)
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To: Jenny217

” But don’t argue with the holier than thou. It’s always a lifestyle choice according to them.”

It’s a religion with some people, and they are incapable—intellectually and emotionally—of accepting that obesity might be a matter of lipid regulation rather than moral turpitude.

The Church of the Immoral Fatso keens incessantly like a grieving banshee that every fat deposit is punishment for the loathsome perversion of over-eating, than which no sin is greater. Every fatso is guilty! Every fatso must be punished! All scientific findings to the contrary must be treated like leftists treat liberty!

It’s really not that hard to see the problem with the “calories in/calories out” nonsense. If not for the bigotry of the Church of the Immoral Fatso, science would be free to acknowledge the truth.

If normal people maintain a normal weight on a normal diet, and the vast majority did until recent decades, then why do some people become obese on a normal diet? The Church of the Immoral Fatso, of course, insists that all such reports are lies, and that the immoral fatsos were secretly over-eating. All scientific evidence to the contrary—and there’s a bunch—is simply denied.


47 posted on 07/17/2014 10:39:02 AM PDT by dsc (Any attempt to move a government to the left is a crime against humanity.)
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To: minnesota_bound

“Won’t be of much use as high fructose corn syrup is in nearly everything.”

Take a page from the leftard handbook: get a federal judge to ban it.


48 posted on 07/17/2014 10:40:45 AM PDT by dsc (Any attempt to move a government to the left is a crime against humanity.)
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To: Innovative

“It doesn’t look like they are restricting who can purchase it and it’s not even very expensive, given that one dose could provide full cure.”

The article says one dose was effective for up to four weeks.


49 posted on 07/17/2014 10:44:41 AM PDT by dsc (Any attempt to move a government to the left is a crime against humanity.)
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To: E. Pluribus Unum

Ain’t it the truth... Possible cures for cancer, Alzheimers, diabetes etc. Don’t want to rush them to market. Might prove harmful to terminally ill patients. /s


50 posted on 07/17/2014 10:59:22 AM PDT by daler
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping...


51 posted on 07/17/2014 1:58:57 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: Innovative

If anyone develops a one-shot cure for Type-II Diabetes, they can retire to Monaco and divide their time between the mansion and the yacht.

And they’ll be driven between the two in a chauffeured Rolls Royce.


52 posted on 07/17/2014 2:37:18 PM PDT by Jack Hammer
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To: Jack Hammer

Gee, could you introduce me...Monaco sounds perfect.


53 posted on 07/17/2014 2:37:52 PM PDT by Kackikat (ELECTED officials took an OATH...get off your cowardly a$ses and be A PATRIOT now!)
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To: Kackikat

Actually, I was being a shade too modest in my terms.

Anyone these days who develops a one-shot cure for Type-II Diabetes could probably buy Geneva, Switzerland.

And throw in Zurich for chump change.


54 posted on 07/17/2014 2:41:22 PM PDT by Jack Hammer
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To: Innovative

While this sounds promising as a treatment, it is still a long way from a cure. The basic problem is that the islets of Langerhans are shutting or have shut down. While this treatment might mitigate one of their processes, it likely does not significantly impact the others.

http://en.wikipedia.org/wiki/Islets_of_Langerhans

Not too long ago, it was discovered that some diabetics still had some functioning islets, but that they were blocked by fat deposits. So a one or two month hospitalization starvation regimen was tried with some success to break the logjam, as it were.

But this didn’t affect those islets that had already shut down. Likewise, the body has insulin receptors that may be a completely different problem if they malfunction.


55 posted on 07/17/2014 4:01:12 PM PDT by yefragetuwrabrumuy ("Don't compare me to the almighty, compare me to the alternative." -Obama, 09-24-11)
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To: txrefugee
If this is successful, it will have to cost $10,000 per shot to make the diabetes industry happy.

I've yet to hear a severe heart attack victim say "wait, how much is this going to cost me?".....LOL!

56 posted on 07/17/2014 4:07:15 PM PDT by Hot Tabasco (By now, everyone should know that you shoot a zombie in the head. Don't try to reason with them...)
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To: FatherofFive
Type 2 diabetes is completely preventable and completely treatable controllable with diet and exercise. And Statins are the biggest medical scam in history.

Fixed it for you...

Statins are not the biggest scam in history...AGW global warming is the biggest scam...Statins is a close second...

After losing 50 lbs and really controlling what I stick in my pie hole, I took myself off my Janumet to see what my blood sugar runs every morning...

Trending...good..

57 posted on 07/17/2014 4:19:24 PM PDT by Popman ("Resistance to Tyrants is Obedience to God" - Thomas Jefferson)
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To: Smokin' Joe

Thanks for the ping!


58 posted on 07/17/2014 6:37:11 PM PDT by Alamo-Girl
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To: Innovative

Bookmark.

I think it will be several years before there is anything available for people to take, as opposed to mouse experiments, but this is certainly promising news.


59 posted on 07/17/2014 6:46:32 PM PDT by Cicero (Marcus Tullius)
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To: Alamo-Girl

You’re Welcome, Alamo-Girl!


60 posted on 07/17/2014 7:30:05 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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