Yes, physically descendant. Theoretically, the peoples of the Lost Ten Tribes did not die off, they were taken into ‘another country’ which was the custom of the time, just as the Jews were taken into Babylon, many years later.
Eventually, the Assyrian Empire fell to other nations, but unlike the Jews of Babylon, the people of the Lost Ten Tribes did not return to their homeland. They had lost their identity as a separate people, mainly because they had rejected God when they lived in Samaria and continued to do so after they went into captivity, essentially becoming pagans themselves, knowing nothing of God.
Interestingly, some of their descendants, a few centuries later, became Christians being evangelized by the early Christian Jews, and became the Iranian and Iraqi Christians we know are persecuted to this day........
Still not understanding how Japhethites and Hamites can be physical descendants of Shemites.