Many have taught in the past, and some still teach, that the Old Testament passages referring to the great tribulation were all fulfilled in the days of Israels sufferings under the nations, after the fall of Jerusalem, particularly in the era of Antiochus Epiphanes, who is sometimes called the Old Testament antichrist....... But a careful examination of the scriptures of the prophets having to do with this time of trial, and a comparison of these with New Testament declarations, make this position absolutely untenable.
Others have supposed that the great tribulation referred either to the days of persecution under pagan emperors of Rome for two bloody centuries, following the death of the apostle Paul, or perhaps the even more fearful persecutions under the papacy during the dark ages. But there are very definite statements made by our Lord Jesus Christ Himself that positively negate any such view and make it evident that this solemn period of judgement is still ‘in the future’
Here here ...
A careful examination of the book of the Apocalypse, of Jesus’ prophetic sayings in the book of Matthew, of the words of Isaiah, Jeremiah, Daniel and Hosea say that the great tribulation and the destruction of the 2nd Temple is what the book of the Apocalypse refers to - Jesus Christ Himself prophesied the destruction of the Temple and that is what the book of hte Apocalypse refers to