How The Catholic Church Built Western Civilization
Americas Catholic Colony [Ecumenical]
The Catholic Church in the United States of America [Ecumenical]
Catholic Founding Fathers - The Carroll Family [Ecumenical]
Charles Carroll, founding father and "an exemplar of Catholic and republican virtue" [Ecumenical]
“Oldest church structure in the U.S. The original adobe walls and altar were built by Tlaxcala Indians from Mexico under the direction of Franciscan Padres, circa 1610”
http://www.evanderputten.org/special/newmexico/sanmiguel.htm
Most earlier records regarding Spanish involvement in Chesapeake Bay are lost of course, but to give you an idea what they could do they actually sailed up the Susquehanna to survey the line between Acadia and Virginia ~ we know that because archaeologists found one of their boats in the mud, as well as Spanish artifacts, armor, skeletons ~ if you can sail up the Susquehanna you can explore and make use of Chesapeake Bay as well.
Then there were the pirates in Maryland ~ the Spanish and the Brits cooperated to a degree in clearing out pirates in the Carribean in the mid 1500s! This is where those guys went ~ and later on in later centuries ~ lots of wild country there until the 1800s.