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One sentence:
Last a hell of a lot longer than 2 days.

The problem with the safe room is exactly the same problem as the fallout shelter: eventually you have to leave and chances are the area immediately around your safe room will be contaminated. Weather might have cleaned up the outside, but there's no weather in your house, and you've specifically chosen an interior room. NBC particles have collected in the rest of your house just like dust (I've lived in Southern Arizona for over a quarter of a century, I could right a doctoral thesis on dust... but it would be very dry! that's a joke, lighten up people) and are more than likely still quite active and dangerous. You've got to clean them out somehow, and your method of cleaning has to make sure that you don't get any on your skin or in your lungs.

See anybody who thinks you can just hide in your safe room for two days and come out and everything will be hunky-dory is just plain wrong. That's only step one, and if you don't take steps 2 through whatever step one was a complete waste of time. And it's only if your neighborhood actually gets attacked, given the sheer size of the country more than likely it won't.